Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Krista L, Denning"'
Autor:
Xue Chen, Long Wang, Krista L. Denning, Anna Mazur, Yujuan Xu, Kesheng Wang, Logan M. Lawrence, Xiaodong Wang, Yongke Lu
Publikováno v:
Biomedicines, Vol 12, Iss 5, p 988 (2024)
Obesity results in hepatic fat accumulation, i.e., steatosis. In addition to fat overload, impaired fatty acid β-oxidation also promotes steatosis. Fatty acid β-oxidation takes place in the mitochondria and peroxisomes. Usually, very long-chain and
Externí odkaz:
https://doaj.org/article/7fc25d7d4436468890e0ceb0ba294ced
Cardiac Glycosides Increase Temozolomide Anticancer Activity in Therapy Resistant Glioblastoma Cells
Publikováno v:
International Journal of Translational Medicine, Vol 2, Iss 2, Pp 148-155 (2022)
Glioblastomas (GBMs) are a form of malignant gliomas characterized by a dismal prognosis. Standard treatment for glioblastoma patients is combined maximal surgical removal of the tumor with postoperative radiotherapy and concomitant chemotherapy with
Externí odkaz:
https://doaj.org/article/87d4a0f7bd0e4535b5d882d993a218f4
Autor:
Kathleen C. Brown, Kushal J. Modi, Reagan S. Light, Ashley J. Cox, Timothy E. Long, Rama S. Gadepalli, John M. Rimoldi, Sarah L. Miles, Gary Rankin, Monica Valentovic, Krista L. Denning, Maria T. Tirona, Paul T. Finch, Joshua A. Hess, Piyali Dasgupta
Publikováno v:
Journal of Medicinal Chemistry. 66:4294-4323
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32a804c7c1f00bc606e3d8948614846d
https://doi.org/10.1021/acs.jmedchem.2c01594
https://doi.org/10.1021/acs.jmedchem.2c01594
Autor:
Tulika Ranjan, Candace M. Howard, Alexander Yu, Linda Xu, Khaled Aziz, David Jho, Jodi Leonardo, Muhammad A. Hameed, Stephen M. Karlovits, Rodney E. Wegner, Russell Fuhrer, Seth T. Lirette, Krista L. Denning, Jagan Valluri, Pier Paolo Claudio
Publikováno v:
Translational Oncology, Vol 13, Iss 4, Pp - (2020)
BACKGROUND: Chemotherapy-resistant cancer stem cells (CSC) may lead to tumor recurrence in glioblastoma (GBM). The poor prognosis of this disease emphasizes the critical need for developing a treatment stratification system to improve outcomes throug
Externí odkaz:
https://doaj.org/article/8900699bf5f1497cb50c4ac12498f170
Publikováno v:
Biochemical and Biophysical Research Communications. 613:47-52
Peroxisome proliferator-activated receptor α (PPARα) regulates fatty acid oxidation (FAO). Usually, very-long chain fatty acids are first activated by acyl-CoA synthetase (ACS) to generate acyl-CoA for oxidation by acyl-CoA oxidase (ACOX) in peroxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::320d1fead976171bb49a591ae30c2122
https://doi.org/10.1016/j.bbrc.2022.04.132
https://doi.org/10.1016/j.bbrc.2022.04.132
Autor:
Anisha Valluri, Jessica Wellman, Chelsea L. McCallister, Kathleen C. Brown, Logan Lawrence, Rebecca Russell, James Jensen, James Denvir, Monica A. Valentovic, Krista L. Denning, Travis B. Salisbury
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 11; Pages: 9364
The mechanistic target of rapamycin (mTOR) kinase is a component of two signaling complexes that are known as mTOR complex 1 (mTORC1) and mTORC2. We sought to identify mTOR-phosphorylated proteins that are differently expressed in clinically resected
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6458c4ee4c10aca9b8b1bfc657976a3
Publikováno v:
Arthroplasty Today, Vol 11, Iss, Pp 81-87 (2021)
Arthroplasty Today
Arthroplasty Today
Arthroplasty implants are comprised of metal alloys designed to function within the human body. Implant-related issues and associated soft-tissue reactions have been well documented for modular revision hip and knee constructs. This case highlights f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75ec3e4578d4f5a9d75cf30be71b41c6
https://doi.org/10.1016/j.artd.2021.07.002
https://doi.org/10.1016/j.artd.2021.07.002
Autor:
Mark Castle, Meghan Pauley, Chadd Mays, Lars Bellner, Marji McCoy, Michal L. Schwartzman, Deborah L. Preston, Casey Patick, Matthew Nudelman, Joseph Werthammer, James R. Bailes, Krista L. Denning
Publikováno v:
Metabolic Syndrome and Related Disorders. 19:281-287
Background: Obesity affects ∼20% of children in the United States and reports of successful dietary treatment are lacking. This study aimed to determine the change in body weight in severely obese ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fd42111603139a3ef9f46d48b2fb179
https://doi.org/10.1089/met.2020.0078
https://doi.org/10.1089/met.2020.0078
Autor:
Tulika Ranjan, Soma Sengupta, Michael J. Glantz, Richard M. Green, Alexander Yu, Dawit Aregawi, Rekha Chaudhary, Ricky Chen, Mario Zuccarello, Christine Lu-Emerson, Hugh D. Moulding, Neil Belman, Jon Glass, Aaron Mammoser, Mark Anderson, Jagan Valluri, Nicholas Marko, Jason Schroeder, Steven Jubelirer, Frances Chow, Pier Paolo Claudio, Anthony M. Alberico, Seth T. Lirette, Krista L. Denning, Candace M. Howard
Publikováno v:
Cell Reports Medicine. 4:101025
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae269c1a9d41e7dcb99f3702028b4787
https://doi.org/10.1016/j.xcrm.2023.101025
https://doi.org/10.1016/j.xcrm.2023.101025
Autor:
Stephen D. Richbart, Nicholas A. Nolan, Austin T. Akers, Kathleen C. Brown, Krista L. Denning, Richard D. Egleton, Piyali Dasgupta
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6765b847524f92b72f55743a39c1f584
https://doi.org/10.1096/fasebj.2022.36.s1.l6395
https://doi.org/10.1096/fasebj.2022.36.s1.l6395