Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Krista Kokki"'
Autor:
Linda van den Berg, Krista Kokki, Sylvia J. Wowro, Konstantin M. Petricek, Onur Deniz, Catrin A. Stegmann, Marius Robciuc, Mari Teesalu, Richard G. Melvin, Anni I. Nieminen, Michael Schupp, Ville Hietakangas
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112739- (2023)
Summary: The ability to feed on a sugar-containing diet depends on a gene regulatory network controlled by the intracellular sugar sensor Mondo/ChREBP-Mlx, which remains insufficiently characterized. Here, we present a genome-wide temporal clustering
Externí odkaz:
https://doaj.org/article/65971c572d3b492db9e0387223bacef0
Autor:
Krista Kokki, Nicole Lamichane, Anni I Nieminen, Hanna Ruhanen, Jack Morikka, Marius Robciuc, Bohdana M Rovenko, Essi Havula, Reijo Käkelä, Ville Hietakangas
Publikováno v:
PLoS Genetics, Vol 17, Iss 10, p e1009855 (2021)
Nutrient-dependent gene regulation critically contributes to homeostatic control of animal physiology in changing nutrient landscape. In Drosophila, dietary sugars activate transcription factors (TFs), such as Mondo-Mlx, Sugarbabe and Cabut, which co
Externí odkaz:
https://doaj.org/article/71bd6816e9024bfd8d0a75273ba21b04
Autor:
Richard G Melvin, Nicole Lamichane, Essi Havula, Krista Kokki, Charles Soeder, Corbin D Jones, Ville Hietakangas
Publikováno v:
eLife, Vol 7 (2018)
How dietary selection affects genome evolution to define the optimal range of nutrient intake is a poorly understood question with medical relevance. We have addressed this question by analyzing Drosophila simulans and sechellia, recently diverged sp
Externí odkaz:
https://doaj.org/article/f7164d3e3229475fa72fb355a09975d8
Autor:
Ville Hietakangas, Krista Kokki, Riikka Hynynen, Reijo Käkelä, Kiran Hasygar, Onur Deniz, Josef Gullmets, Hanna Ruhanen, Ying Liu
Publikováno v:
EMBO Reports
Energy storage and growth are coordinated in response to nutrient status of animals. How nutrient‐regulated signaling pathways control these processes in vivo remains insufficiently understood. Here, we establish an atypical MAP kinase, ERK7, as an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91b140f470043c6ab104ec7da4f9f9f3
http://europepmc.org/articles/PMC7857433
http://europepmc.org/articles/PMC7857433
Autor:
Essi Havula, Marius R. Robciuc, Bohdana M. Rovenko, Ville Hietakangas, Krista Kokki, Anni I. Nieminen, Nicole Lamichane, Reijo Käkelä, Jack Morikka, Hanna Ruhanen
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 17, Iss 10, p e1009855 (2021)
PLoS Genetics, Vol 17, Iss 10, p e1009855 (2021)
Nutrient-dependent gene regulation critically contributes to homeostatic control of animal physiology in changing nutrient landscape. In Drosophila, dietary sugars activate transcription factors (TFs), such as Mondo-Mlx, Sugarbabe and Cabut, which co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4450c9dab5ef3f7c5df45f3f6db0e40a
https://doi.org/10.1371/journal.pgen.1009855
https://doi.org/10.1371/journal.pgen.1009855
Autor:
Nikolay Naumenko, Smirin Bv, Pasi Tavi, Svetlana Laidinen, Jenni Huusko, Maija Mutikainen, Krista Kokki, Jorge L. Ruas, Seppo Ylä-Herttuala, Tomi Tuomainen, Merja Heinäniemi, Heidi Hynynen
Publikováno v:
The Journal of Physiology. 594:7049-7071
Key points Transcriptional co-activator PGC-1α1 has been shown to regulate energy metabolism and to mediate metabolic adaptations in pathological and physiological cardiac hypertrophy but other functional implications of PGC-1α1 expression are not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bdce6e59c9732f5c4a4235b76bb9423d
https://doi.org/10.1113/jp272847
https://doi.org/10.1113/jp272847
Autor:
Nicole Lamichane, Corbin D. Jones, Ville Hietakangas, Krista Kokki, Richard G. Melvin, Charles Soeder, Essi Havula
Publikováno v:
eLife
eLife, Vol 7 (2018)
eLife, Vol 7 (2018)
How dietary selection affects genome evolution to define the optimal range of nutrient intake is a poorly understood question with medical relevance. We have addressed this question by analyzing Drosophila simulans and sechellia, recently diverged sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3db04df0fe40fcc2d316c5183c81d862
https://doi.org/10.7554/elife.40841
https://doi.org/10.7554/elife.40841
Publikováno v:
Developmental Cell
Summary The intestine is an organ with an exceptionally high rate of cell turnover, and perturbations in this process can lead to severe diseases such as cancer or intestinal atrophy. Nutrition has a profound impact on intestinal volume and cellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0928ca2405a8f10ff78ac9ca42553c0
http://hdl.handle.net/10138/299365
http://hdl.handle.net/10138/299365
Autor:
Kokki, Krista1,2 (AUTHOR), Lamichane, Nicole1,2 (AUTHOR), Nieminen, Anni I.1,2 (AUTHOR), Ruhanen, Hanna1,3 (AUTHOR), Morikka, Jack1,2 (AUTHOR), Robciuc, Marius1,2 (AUTHOR), Rovenko, Bohdana M.1,2 (AUTHOR), Havula, Essi4 (AUTHOR), Käkelä, Reijo1,3 (AUTHOR), Hietakangas, Ville1,2 (AUTHOR) ville.hietakangas@helsinki.fi
Publikováno v:
PLoS Genetics. 10/11/2021, Vol. 17 Issue 10, p1-28. 28p.