Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Krista John-Williams"'
Autor:
Mausam Patel, Daniela Rodriguez, Keyvan Yousefi, Krista John-Williams, Armando J. Mendez, Ronald B. Goldberg, Anastasios Lymperopoulos, Leonardo J. Tamariz, Jeffrey J. Goldberger, Robert J. Myerburg, Juhani Junttila, Lina A. Shehadeh
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 7 (2020)
Background: Diabetes mellitus (DM) is associated with increased risk of sudden cardiac death (SCD), particularly in patients with heart failure with preserved ejection fraction (HFpEF). However, there are no known biomarkers in the population with DM
Externí odkaz:
https://doaj.org/article/b76e8fc3ec4142199460b3d0c6c4a50a
Autor:
Camila Iansen Irion, Julian C. Dunkley, Krista John-Williams, José Manuel Condor Capcha, Serene A. Shehadeh, Andre Pinto, Matthias Loebe, Keith A. Webster, Nicolas A. Brozzi, Lina A. Shehadeh
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
BackgroundHeart transplant is the gold standard therapy for patients with advanced heart failure. Over 5,500 heart transplants are performed every year worldwide. Cardiac allograft vasculopathy (CAV) is a common complication post-heart transplant whi
Externí odkaz:
https://doaj.org/article/0316fc2c19f145d097b3e555a08a813d
Osteopontin Expression in Cardiomyocytes Is Increased in Pediatric Patients With Sepsis or Pneumonia
Autor:
Camila Iansen Irion, Kiera Parrish, Krista John-Williams, Sakir H. Gultekin, Lina A. Shehadeh
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Sepsis and pneumonia are major causes of death in the United States, and their pathophysiology includes infection with inflammation and immune dysfunction. Both sepsis and pneumonia cause cardiovascular dysfunction. The expression of Osteopontin (OPN
Externí odkaz:
https://doaj.org/article/073c5b47cd804ab1a2892c264003df13
Autor:
Julian C. Dunkley, Serene A. Shehadeh, Keith A. Webster, Guerline Lambert, Krista John-Williams, Jeffrey J. Goldberger, Lina A. Shehadeh, Camila Iansen Irion, Keyvan Yousefi
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 320:H1862-H1872
In an Alport mouse model of heart failure with preserved ejection fraction (HFpEF), exercise and carvedilol synergistically improved systolic function without affecting diastole. Carvedilol alone or in combination with exercise also improved kidney f
Autor:
Yanelys R Fernandez, Keith A. Webster, Konstantinos E. Hatzistergos, Keyvan Yousefi, Krista John-Williams, Ahmed Chahdi, Joshua M. Hare, Camila Iansen Irion, Lina A. Shehadeh
Publikováno v:
Circulation Research. 125
Background: Our previous work showed that pharmacological blockade of Osteopontin (OPN) signaling can prevent and reverse heart failure induced by pressure overload in a transverse aortic construction (TAC) mouse model. Surprisingly, OPN Knockout (KO
Autor:
Jeffery M. Vance, Gary W. Beecham, Eden R. Martin, Krista John-Williams, Aleena Ali, Lizmarie Maldonado, William K. Scott, Karen Nuytemans
Publikováno v:
Neurology: Genetics
Objective: Given their reported function in phagocytosis and clearance of protein aggregates in Alzheimer disease (AD), we hypothesized that variants in ATP-binding cassette transporter A7 ( ABCA7 ) might be involved in Parkinson disease (PD). Method
Autor:
Gary W. Small, John R. Gilbert, Ruchita Rajbhandary, Krista John-Williams, Martin A. Kohli, Goldie S. Byrd, Clinton B. Wright, Rosalyn Lang, Kara Hamilton, Jonathan L. Haines, Patrice L. Whitehead, Deborah C. Mash, Michael Benatar, Harry E. Gwirtzman, Margaret A. Pericak-Vance, Gary W. Beecham, Regina M. Carney, Elizabeth Crocco, Eden R. Martin, Stephan Züchner, Adam C. Naj
Publikováno v:
Neurobiology of aging. 34(5)
Recently, a hexanucleotide repeat expansion in the C9ORF72 gene has been identified to account for a significant portion of Caucasian families affected by frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). Given the clinical overl
Autor:
Gary W. Beecham, Ruchita Rajbhandary, Krista John-Williams, John R. Gilbert, Kara Hamilton, Patrice L. Whitehead, Eden R. Martin, Stephan Züchner, Timothy Plitnik, Adam C. Naj, Jonathan L. Haines, Margaret A. Pericak-Vance, Martin A. Kohli
Publikováno v:
Alzheimer's & Dementia. 8
Autor:
Jonathan L. Haines, Deborah C. Mash, John R. Gilbert, Margaret A. Pericak-Vance, Krista John-Williams, Timothy Plitnik, Patrice L. Whitehead, Crystal Humphries, Martin A. Kohli
Publikováno v:
Alzheimer's & Dementia. 8
Autor:
Margaret Pericak‐Vance, Stephan Zuchner, Martin Kohli, Krista John‐Williams, Adam Naj, Ruchita Rajbhandary, Patrice L. Whitehead, Kara Hamilton‐Nelson, Regina Carney, Clinton Wright, Elizabeth Crocco, Harry Gwirtzman, Rosalyn Lang, Gary Beecham, Eden Martin, John Gilbert, Michael Benatar, Deborah Mash, Goldie Byrd, Jonathan Haines
Publikováno v:
Alzheimer's & Dementia. 8