Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Krista Freimann"'
Autor:
Krista Freimann, Piret Arukuusk, Kaido Kurrikoff, Ly Pärnaste, Raivo Raid, Andres Piirsoo, Margus Pooga, Ülo Langel
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 10, Iss , Pp 28-35 (2018)
Although advances in genomics and experimental gene therapy have opened new possibilities for treating otherwise incurable diseases, the transduction of nucleic acids into the cells and delivery in vivo remain challenging. The high molecular weight a
Externí odkaz:
https://doaj.org/article/68577712943243b5ade7880decde107e
Autor:
Moataz Dowaidar, Hani Nasser Abdelhamid, Mattias Hällbrink, Krista Freimann, Kaido Kurrikoff, Xiaodong Zou, Ülo Langel
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Magnetic nanoparticles (MNPs, Fe3O4) incorporated into the complexes of cell penetrating peptides (CPPs)-oligonucleotides (ONs) promoted the cell transfection for plasmid transfection, splice correction, and gene silencing efficiencies. Six
Externí odkaz:
https://doaj.org/article/c4631fac3dd145529679391dcb43aa18
Autor:
Kadi-Liis Veiman, Andres Piirsoo, Krista Freimann, Elin Madli Peets, Kaido Kurrikoff, Ülo Langel
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-7 (2019)
Scientific Reports
Scientific Reports
We have previously developed efficient peptide-based nucleic acid delivery vectors PF14 and NF55, where we have shown that these vectors preferentially transfect lung tissue upon systemic administration with the nucleic acid. In the current work, we
Autor:
Dominique Sarah Rosenberg, Mohand Laid Oubaiche, Stylianos E. Antonarakis, Malika Chaouch, Yvonne G. Weber, Carlo Nobile, Ingo Helbig, Corinne Gehrig, Arielle Crespel, Gaetan Lesca, Amina Chentouf, Edouard Hirsch, Felicitas Becker, Massimo Pizzato, Krista Freimann, Annick Salzmann, Philippe Ryvlin, Johannes R. Lemke, Thomas Dorn, Hiltrud Muhle, Federico Santoni, Kristin Webling, Ülo Langel, Michel Guipponi, Gabrielle Rudolf, Jörg Hansen, Serena Ziglio
Publikováno v:
HUMAN MOLECULAR GENETICS
Human Molecular Genetics, Vol. 24, No 11 (2015) pp. 3082-3091
Guipponi, Michel; Chentouf, Amina; Webling, Kristin E.B.; Freimann, Krista; Crespel, Arielle; Nobile, Carlo; Lemke, Johannes R.; Hansen, Jörg; Dorn, Thomas; Lesca, Gaetan; Ryvlin, Philippe; Hirsch, Edouard; Rudolf, Gabrielle; Rosenberg, Dominique Sarah; Weber, Yvonne; Becker, Felicitas; Helbig, Ingo; Muhle, Hiltrud; Salzmann, Annick; Chaouch, Malika; ... (2015). Galanin pathogenic mutations in temporal lobe epilepsy. Human molecular genetics, 24(11), pp. 3082-3091. Oxford University Press 10.1093/hmg/ddv060
Human Molecular Genetics, vol. 24, no. 11, pp. 3082-3091
Human Molecular Genetics, Vol. 24, No 11 (2015) pp. 3082-3091
Guipponi, Michel; Chentouf, Amina; Webling, Kristin E.B.; Freimann, Krista; Crespel, Arielle; Nobile, Carlo; Lemke, Johannes R.; Hansen, Jörg; Dorn, Thomas; Lesca, Gaetan; Ryvlin, Philippe; Hirsch, Edouard; Rudolf, Gabrielle; Rosenberg, Dominique Sarah; Weber, Yvonne; Becker, Felicitas; Helbig, Ingo; Muhle, Hiltrud; Salzmann, Annick; Chaouch, Malika; ... (2015). Galanin pathogenic mutations in temporal lobe epilepsy. Human molecular genetics, 24(11), pp. 3082-3091. Oxford University Press 10.1093/hmg/ddv060
Human Molecular Genetics, vol. 24, no. 11, pp. 3082-3091
Temporal lobe epilepsy (TLE) is a common epilepsy syndrome with a complex etiology. Despite evidence for the participation of genetic factors, the genetic basis of TLE remains largely unknown. A role for the galanin neuropeptide in the regulation of
Autor:
Kaido Kurrikoff, Andres Piirsoo, Krista Freimann, Piret Arukuusk, Ülo Langel, Margus Pooga, Ly Pärnaste, Raivo Raid
Publikováno v:
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 10, Iss, Pp 28-35 (2018)
Molecular Therapy: Nucleic Acids, Vol 10, Iss, Pp 28-35 (2018)
Although advances in genomics and experimental gene therapy have opened new possibilities for treating otherwise incurable diseases, the transduction of nucleic acids into the cells and delivery in vivo remain challenging. The high molecular weight a
Autor:
Kaido Kurrikoff, Alfonso T. García-Sosa, Helerin Margus, Piret Arukuusk, Ülo Langel, Krista Freimann, Kadi-Liis Veiman, Luis Vasconcelos, Margus Pooga, Julia Uusna
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 241
As the field of gene therapy progresses, an increasingly urgent need has arisen for efficient and non-toxic vectors for the in vivo delivery of nucleic acids. Cell-penetrating peptides (CPP) are very efficient transfection reagents in vitro, however,
Publikováno v:
Expert opinion on therapeutic targets. 19(12)
Introduction: Galanin is a 29/30 amino acid long neuropeptide that is widely expressed in the brains of many mammals. Galanin exerts its biological activities through three different G protein-coupled receptors, GalR1, GalR2 and GalR3. The widespread