P150 THE IMPACT OF ARTERIAL STIFFNESS ON TROPONIN T LEVELS IN CHRONIC HAEMODIALYSIS PATIENTS

Autor: Christian Daugaard Peters, Krista Dybtved Kjærgaard, Bente Jespersen, Kent Lodberg Christensen, Jens Dam Jensen

Publikováno v: Artery Research, Vol 24 (2018)

Background: Troponin T (TnT) is a highly specific biomarker for myocardial infarction (MI). Haemodialysis (HD) patients often have increased arterial stiffness and elevated TnT. Previous studies have linked elevated TnT with worse outcome, even in th

Externí odkaz: https://doaj.org/article/1f2e69e86dc946b5b5562eb35dbd37c5

Vitamin K supplementation and arterial calcification in dialysis: results of the double-blind, randomized, placebo-controlled RenaKvit trial

Autor: Hanne Sandstrøm, Jens Brøndum Frøkjær, Jens Dam Jensen, Krista Dybtved Kjaergaard, Marie Frimodt-Møller, Inge Petersen, Charlotte Strandhave, Niels Erik Frandsen, Carsten Toftager Larsen, Jonna Skov Madsen, Anne Schmedes, Ditte Hansen, Karin Levy-Schousboe, Christian Daugaard Peters, Peter Marckmann, Hanne Elming, Niklas Rye Jørgensen, Claus Lohman Brasen

Publikováno v: Clinical Kidney Journal
Levy-Schousboe, K, Frimodt-Møller, M, Hansen, D, Peters, C D, Kjærgaard, K D, Jensen, J D, Strandhave, C, Elming, H, Larsen, C T, Sandstrøm, H, Brasen, C L, Schmedes, A, Madsen, J S, Jørgensen, N R, Frøkjær, J B, Frandsen, N E, Petersen, I & Marckmann, P 2021, ' Vitamin K supplementation and arterial calcification in dialysis : results of the double-blind, randomized, placebo-controlled RenaKvit trial ', Clinical Kidney Journal, vol. 14, no. 9, pp. 2114-2123 . https://doi.org/10.1093/ckj/sfab017
Levy-Schousboe, K, Frimodt-Moller, M, Hansen, D, Peters, C D, Kjaergaard, K D, Jensen, J D, Strandhave, C, Elming, H, Larsen, C T, Sandstrom, H, Brasen, C L, Schmedes, A, Madsen, J S, Jorgensen, N R, Frokjaer, J B, Frandsen, N E, Petersen, I & Marckmann, P 2021, ' Vitamin K supplementation and arterial calcification in dialysis : results of the double-blind, randomized, placebo-controlled RenaKvit trial ', Clinical Kidney Journal, vol. 14, no. 9, pp. 2114-2123 . https://doi.org/10.1093/ckj/sfab017
Levy-Schousboe, K, Frimodt-Møller, M, Hansen, D, Peters, C D, Kjærgaard, K D, Jensen, J D, Strandhave, C, Elming, H, Larsen, C T, Sandstrøm, H, Brasen, C L, Schmedes, A, Madsen, J S, Jørgensen, N R, Frøkjær, J B, Frandsen, N E, Petersen, I & Marckmann, P 2021, ' Vitamin K supplementation and arterial calcification in dialysis: results of the double-blind, randomized, placebo-controlled RenaKvit trial ', Clinical Kidney Journal, vol. 14, no. 9, pp. 2114-2123 . https://doi.org/10.1093/ckj/sfab017

Arterial calcification is associated with cardiovascular mortality in dialysis patients. Active matrix Gla protein (MGP) is a vitamin K-dependent inhibitor of arterial calcification. Elevated plasma concentrations of inactive MGP, i.e. dephosphorylat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e6487522f1063a8592dd613c9af0e4c
http://europepmc.org/articles/PMC8406073

High-sensitivity Troponin T in hemodialysis patients: a randomized placebo-controlled sub-study investigating angiotensin-II-blockade, variation over time and associations with clinical outcome

Autor: Bente Jespersen, Jens Dam Jensen, Bo Martin Bibby, Christian Daugaard Peters, Kent L. Christensen, Krista Dybtved Kjaergaard

Publikováno v: BMC Nephrology
Peters, C D, Kjaergaard, K D, Christensen, K L, Bibby, B M, Jespersen, B & Jensen, J D 2020, ' High-sensitivity Troponin T in hemodialysis patients : a randomized placebo-controlled sub-study investigating angiotensin-II-blockade, variation over time and associations with clinical outcome ', BMC Nephrology, vol. 21, no. 1, 452 . https://doi.org/10.1186/s12882-020-02103-1
BMC Nephrology, Vol 21, Iss 1, Pp 1-15 (2020)

Background Troponin T (TnT) is a well-known risk factor for negative outcome in hemodialysis (HD) patients, but little is known about variation over time, and the impact of clinical and dialysis specific factors. This study investigated the effect of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfb0392e1fcb694218f006c01840e744
https://pubmed.ncbi.nlm.nih.gov/33115436

Long-term effects of angiotensin II blockade with irbesartan on inflammatory markers in hemodialysis patients: A randomized double blind placebo controlled trial (SAFIR study)

Autor: Bente Jespersen, Claus H Nielsen, Jens Dam Jensen, Christian Daugaard Peters, Kent L. Christensen, Krista Dybtved Kjaergaard, Bo Martin Bibby

Publikováno v: Hemodialysis International. 21:47-62

Introduction: Low-grade chronic inflammation is common in hemodialysis (HD) patients. Previous studies suggest an anti-inflammatory effect of angiotensin II receptor blocker (ARB) treatment. The aim of this study was to compare the effect of ARB vs.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fc3b94704516c738cc225b73cd540358
https://doi.org/10.1111/hdi.12436

Brain swelling during dialysis: A randomized trial comparing low-flux hemodialysis with pre-dilution hemodiafiltration

Autor: Bente Jespersen, Jens Dam Jensen, Niels Johansen, Christian Daugaard Peters, Michael Pedersen, Krista Dybtved Kjaergaard

Publikováno v: Johansen, N, Kjaergaard, K D, Peters, C D, Pedersen, M, Jespersen, B & Jensen, J D 2017, ' Brain swelling during dialysis: A randomized trial comparing low-flux hemodialysis with pre-dilution hemodiafiltration ', Clinical Nephrology, vol. 87, no. 5, pp. 221-230 . https://doi.org/10.5414/CN108931

Osmotic changes in plasma are assumed to cause cerebral swelling in hemodialysis patients. We investigated the acute effect of low-flux hemodialysis (HD) (removal of small molecules) and pre-dilution hemodiafiltration (pre-HDF) (additional removal of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::697072dbe02a5105c2931e3ad535fe6f
https://pubmed.ncbi.nlm.nih.gov/28332474