Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Krista D Stackley"'
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59218 (2013)
Opa1 catalyzes fusion of inner mitochondrial membranes and formation of the cristae. OPA1 mutations in humans lead to autosomal dominant optic atrophy. OPA1 knockout mice lose viability around embryonic day 9 from unknown reasons, indicating that OPA
Externí odkaz:
https://doaj.org/article/d5fc080521d74891a7610b99f9922bec
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25652 (2011)
Many debilitating conditions are linked to bioenergetic defects. Developing screens to probe the genetic and/or chemical basis for such links has proved intractable. Furthermore, there is a need for a physiologically relevant assay of bioenergetics i
Externí odkaz:
https://doaj.org/article/9ed4560aeb7d42c594becd9289075565
Publikováno v:
Nucleic Acids Research
DNA polymerase gamma (POLG) is essential for replication and repair of mitochondrial DNA (mtDNA). Mutations in POLG cause mtDNA instability and a diverse range of poorly understood human diseases. Here, we created a unique Polg animal model, by modif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12e1ad06da09c61ca541842706864a25
http://europepmc.org/articles/PMC4666367
http://europepmc.org/articles/PMC4666367
Autor:
Krista D. Stackley, Sherine S.L. Chan, Tucker Williamson, Jennifer J. Rahn, Jennifer E. Bestman
Publikováno v:
Differentiation. 89:51-69
The etiology of mitochondrial disease is poorly understood. Furthermore, treatment options are limited, and diagnostic methods often lack the sensitivity to detect disease in its early stages. Disrupted oxidative phosphorylation (OXPHOS) that inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::878a43b2da8f2c987eea96b3624f33e9
https://doi.org/10.1016/j.diff.2015.01.001
https://doi.org/10.1016/j.diff.2015.01.001
Autor:
Jennifer J. Rahn, C.J. Chou, Benjamin J. Josey, E.S. Inks, Sherine S.L. Chan, Krista D. Stackley, Jennifer E. Bestman, C.E. Rogers
Publikováno v:
Neuroscience. 259:142-154
Epilepsy is a debilitating disease affecting 1-2% of the world's population. Despite this high prevalence, 30% of patients suffering from epilepsy are not successfully managed by current medication suggesting a critical need for new anti-epileptic dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::333248068f141ffa4cb9a2fa5047c7d6
https://doi.org/10.1016/j.neuroscience.2013.11.040
https://doi.org/10.1016/j.neuroscience.2013.11.040
Autor:
Steven M. Claypool, Oleh Khalimonchuk, Jennifer E. Bestman, Robert E. Lewis, Rodrigo Franco, Krista D. Stackley, Jennifer J. Rahn, Sherine S.L. Chan, Mario R. Fernandez, Annadurai Anandhan, Iryna Bohovych
Publikováno v:
Scientific Reports
Mitochondria are involved in key cellular functions including energy production, metabolic homeostasis and apoptosis. Normal mitochondrial function is preserved by several interrelated mechanisms. One mechanism – intramitochondrial quality control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ce001e362b263eb50c6748627f4d415
Autor:
Ashley Duquette, Susan B. Wilde, Abby Goodson, Krista D. Stackley, Charles J. Keppler, Dianne I. Greenfield, Larissa M. Brock, Sarah H. Williams, David White
Publikováno v:
Environmental management. 54(5)
Toxic cyanobacteria blooms are a growing concern for public health and safety, due in part to the production of the hepatotoxin microcystin by certain species, including Microcystis aeruginosa. Management strategies for controlling cyanobacteria bloo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1c4af94b85763625e8a3b727a55fc24
https://pubmed.ncbi.nlm.nih.gov/25078538
https://pubmed.ncbi.nlm.nih.gov/25078538
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59218 (2013)
PLoS ONE
PLoS ONE
Opa1 catalyzes fusion of inner mitochondrial membranes and formation of the cristae. OPA1 mutations in humans lead to autosomal dominant optic atrophy. OPA1 knockout mice lose viability around embryonic day 9 from unknown reasons, indicating that OPA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0db43ea8d8226d58ea58e9947e5108be
http://europepmc.org/articles/PMC3597633?pdf=render
http://europepmc.org/articles/PMC3597633?pdf=render
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 9, p e25652 (2011)
PLoS ONE, Vol 6, Iss 9, p e25652 (2011)
Many debilitating conditions are linked to bioenergetic defects. Developing screens to probe the genetic and/or chemical basis for such links has proved intractable. Furthermore, there is a need for a physiologically relevant assay of bioenergetics i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f93036a844fd459996d7ecba562589df
https://doi.org/10.1371/journal.pone.0025652
https://doi.org/10.1371/journal.pone.0025652