Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Krista Burke"'
Autor:
Holly Koblish, Yun-Long Li, Niu Shin, Leslie Hall, Qian Wang, Kathy Wang, Maryanne Covington, Cindy Marando, Kevin Bowman, Jason Boer, Krista Burke, Richard Wynn, Alex Margulis, Gary W Reuther, Que T Lambert, Valerie Dostalik Roman, Ke Zhang, Hao Feng, Chu-Biao Xue, Sharon Diamond, Greg Hollis, Swamy Yeleswaram, Wenqing Yao, Reid Huber, Kris Vaddi, Peggy Scherle
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0199108 (2018)
The Proviral Integration site of Moloney murine leukemia virus (PIM) serine/threonine protein kinases are overexpressed in many hematologic and solid tumor malignancies and play central roles in intracellular signaling networks important in tumorigen
Externí odkaz:
https://doaj.org/article/171a9a5db0614099bf5185681e8619f9
Autor:
Nina Zolotarjova, Christopher Maddage, Krista Burke, April Horsey, Hao Liu, Christina Stevens, David A. Reardon, Chrysi Kanellopoulou, Prafulla C. Gokhale, Holly Koblish, Darlise DiMatteo, Gengjie Yang, Kanishk Kapilashrami, Yan-ou Yang, Jonathan Rios-Doria, Leslie Hall, Maryanne Covington, Mark Rupar, Richard Wynn, Alla Volgina, Pramod Thekkat, Steve Wang, Phillip Liu, Elham Behshad
Publikováno v:
Journal for ImmunoTherapy of Cancer. 9:A247-A247
BackgroundBlocking the PD-L1 immune checkpoint axis with therapeutic antibodies against either the ligand or PD-1 has proven to be an effective treatment modality for multiple cancer histologies. Small molecules targeting the PD-L1/PD-1 axis represen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd81941c06e77aacef0219db6a69514e
https://doi.org/10.1136/jitc-2021-sitc2021.232
https://doi.org/10.1136/jitc-2021-sitc2021.232
Autor:
Rina Pan, Krista Burke, Swamy Yeleswaram, Jennifer Harris, Sharon Diamond, Michelle Conlin, Indushekhar Persaud
Publikováno v:
International Journal of Pharmaceutics. 590:119889
This preclinical study compared plasma concentrations and distribution of ruxolitinib in the skin of Gottingen minipigs following twice a day oral (40 mg/kg) versus topical administration (1.5% w/w cream applied to 10% of body surface area). Followin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94861535dabf9deca06c4bd830d079df
https://doi.org/10.1016/j.ijpharm.2020.119889
https://doi.org/10.1016/j.ijpharm.2020.119889
Autor:
Sharon Diamond, Taisheng Huang, Karen Gallagher, Jun Li, Brittany Fay, Monika Scuron, Michael Peel, Robert C. Newton, Niu Shin, Ashish Juvekar, Peggy Scherle, Xin He, Julian Oliver, Robert Collins, Chu-Biao Xue, Krista Burke, Yan Zhang, Paul Smith, Wenqing Yao, Maryanne Covington, Margaret Favata, Sarala Sarah
Publikováno v:
European Journal of Pharmacology. 885:173505
Pharmacological modulation of the Janus kinase (JAK) family has achieved clinically meaningful therapeutic outcomes for the treatment of inflammatory and hematopoietic diseases. Several JAK1 selective compounds are being investigated clinically to de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b303ded56282c591cd24d94685b79bfe
https://doi.org/10.1016/j.ejphar.2020.173505
https://doi.org/10.1016/j.ejphar.2020.173505
Autor:
Sharon Diamond, Gregory Hollis, Yue Zhang, Reid Huber, Christina Stevens, Liangxing Wu, Sybil O'Connor, Ashwini Kulkarni, Krista Burke, Peggy Scherle, Kaijiong Xiao, Jingwei Li, Karen Gallagher, Maryanne Covington, Yan-ou Yang, Michael Hansbury, Wenqing Yao, Gengjie Yang, Jonathan Rios-Doria, Holly Koblish, Liang-Chuan S. Wang
Publikováno v:
Cancer Research. 79:4480-4480
Monoclonal antibodies against PD-L1 or PD-1 have been approved for the treatment of multiple tumor histologies by virtue of their ability to restore T cell effector function, increase T cell proliferation and enhance infiltration of tumor-reactive T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbba385dc8588d95cff7c988f35ee11b
https://doi.org/10.1158/1538-7445.am2019-4480
https://doi.org/10.1158/1538-7445.am2019-4480
Autor:
Que T. Lambert, Kevin Bowman, Jason Boer, Gary W. Reuther, Valerie Roman, Peggy Scherle, Reid Huber, Krista Burke, Leslie Hall, Chu-Biao Xue, Kris Vaddi, Niu Shin, Yun-Long Li, Sharon Diamond, Alex Margulis, Qian Wang, Maryanne Covington, Greg Hollis, Swamy Yeleswaram, Holly Koblish, Hao Feng, Wenqing Yao, Cindy A. Marando, Richard Wynn, Ke Zhang, Kathy Wang
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0199108 (2018)
PLoS ONE
PLoS ONE
The Proviral Integration site of Moloney murine leukemia virus (PIM) serine/threonine protein kinases are overexpressed in many hematologic and solid tumor malignancies and play central roles in intracellular signaling networks important in tumorigen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23a13c3f135485d7c8617d5925c8861a
https://doi.org/10.1371/journal.pone.0199108
https://doi.org/10.1371/journal.pone.0199108
Autor:
Alan Roberts, Sang Hyun Lee, Sybil O'Connor, Swamy Yeleswaram, Liangxing Wu, Alexander Margulis, Wenqing Yao, Gengjie Yang, Valerie Roman, Bruce Ruggeri, Krista Burke, Yan Zhang, Kevin Bowman, Dana Shuey, Yan-ou Yang, Sharon Diamond, Reid Huber, Gregory Hollis, Maxim Soloviev, Richard Wynn, Peggy Scherle, Timothy Burn
Publikováno v:
Blood. 128:2472-2472
Sickle cell disease (SCD) is an autosomal recessive genetic disorder caused by a point mutation in the human β-globin gene. Patients harboring this mutation can exhibit long-chain polymers of hemoglobin and sickle-shaped red blood cells, and suffer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7c84a7e161dd26bdf2bf26be7a710ce
https://doi.org/10.1182/blood.v128.22.2472.2472
https://doi.org/10.1182/blood.v128.22.2472.2472
Autor:
Niu Shin, Lynn Leffet, Reid Huber, Leslie Hall, Sybil O'Connor, Peggy Scherle, Wenqing Yao, Holly Koblish, Kris Vaddi, Qian Wang, Maryanne Covington, Krista Burke, Chu-Biao Xue, Jason Boer, Ke Zhang, Kathy Wang, Hao Feng, Yun-Long Li, Kevin Bowman
Publikováno v:
Cancer Research. 75:5416-5416
The PIM family of serine-threonine protein kinases (PIM1, PIM2 and PIM3) was initially identified as preferential integration sites of the Moloney murine leukemia virus in Eμ-myc mice, resulting in perinatal lymphomagenesis. Molecular characterizati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b5a6b96753c1200ff229d636f4d2c65
https://doi.org/10.1158/1538-7445.am2015-5416
https://doi.org/10.1158/1538-7445.am2015-5416
Autor:
Wenqing Yao, Krista Burke, Valerie Dostalik, Qian Wang, Peggy Scherle, Xiaoming Wen, Maryanne Covington, Holly Koblish, Kris Vaddi, Ke Zhang, Kathy Wang, Reid Huber, Leslie Hall, Jason Boer, Kevin Bowman, Sybil O'Connor, Yun-Long Li, Cindy A. Marando, Hao Feng, Niu Shin, Chu-Biao Xue
Publikováno v:
Cancer Research. 75:5414-5414
The PIM family of serine-threonine protein kinases (PIM1, PIM2 and PIM3) mediates responses to cytokines and growth factors and drives cell proliferation and survival in a number of hematologic malignancies. Overexpression of PIM kinases in these mal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eea9f7726f3d0e0b793dd59b606402ad
https://doi.org/10.1158/1538-7445.am2015-5414
https://doi.org/10.1158/1538-7445.am2015-5414