Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Krista A Matthews"'
Autor:
Russell P Swift, Krithika Rajaram, Hans B Liu, Amanda Dziedzic, Anne E Jedlicka, Aleah D Roberts, Krista A Matthews, Hugo Jhun, Namandje N Bumpus, Shivendra G Tewari, Anders Wallqvist, Sean T Prigge
Publikováno v:
PLoS Pathogens, Vol 16, Iss 2, p e1008316 (2020)
Malaria parasites rely on a plastid organelle for survival during the blood stages of infection. However, the entire organelle is dispensable as long as the isoprenoid precursor, isopentenyl pyrophosphate (IPP), is supplemented in the culture medium.
Externí odkaz:
https://doaj.org/article/ae89fcfe1c5546e892dac3f249d96b6d
Autor:
Jolyn E Gisselberg, Teegan A Dellibovi-Ragheb, Krista A Matthews, Gundula Bosch, Sean T Prigge
Publikováno v:
PLoS Pathogens, Vol 9, Iss 9, p e1003655 (2013)
The apicoplast organelle of the malaria parasite Plasmodium falciparum contains metabolic pathways critical for liver-stage and blood-stage development. During the blood stages, parasites lacking an apicoplast can grow in the presence of isopentenyl
Externí odkaz:
https://doaj.org/article/a9ed6a1eabf24ceb8aaa99934584e594
Autor:
Filipa Rijo-Ferreira, Christopher A. Gonzales, Elisabeth D. Martinez, Krista Ann Matthews, Natarajan V. Bhanu, Xinran Tong, Celia Miguel-Blanco, Björn F.C. Kafsack, Maria Jose Lafuente-Monasterio, Christopher Nötzel, Benjamin A. Garcia, Kossi Mawududzi Senagbe
Publikováno v:
ACS Infectious Diseases
Little is known about the role of the three Jumonji C (JmjC) enzymes in Plasmodium falciparum (Pf). Here, we show that JIB-04 and other established inhibitors of mammalian JmjC histone demethylases kill asexual blood stage parasites and are even more
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be822cd1637b376711ed444792da782e
http://europepmc.org/articles/PMC7748244
http://europepmc.org/articles/PMC7748244
Autor:
Krista Ann Matthews, Namandjé N. Bumpus, Hugo Jhun, Hans B. Liu, Krithika Rajaram, Sean T. Prigge, Aleah D. Roberts, Anne E. Jedlicka, Russell P. Swift, Amanda Dziedzic, Shivendra G. Tewari, Anders Wallqvist
Publikováno v:
PLoS Pathogens, Vol 16, Iss 2, p e1008316 (2020)
PLoS Pathogens
PLoS Pathogens
Malaria parasites rely on a plastid organelle for survival during the blood stages of infection. However, the entire organelle is dispensable as long as the isoprenoid precursor, isopentenyl pyrophosphate (IPP), is supplemented in the culture medium.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84170ac1cfbf56f90cbc1cbd4ab20b7e
https://doi.org/10.1371/journal.ppat.1008316
https://doi.org/10.1371/journal.ppat.1008316
Autor:
Satish Mishra, Krithika Rajaram, Sean T. Prigge, Christopher D. Goodman, Teegan A. Dellibovi-Ragheb, Photini Sinnis, Daniel R.T. Ragheb, Geoffrey I. McFadden, Maroya S. Walters, Krista Ann Matthews, Hugo Jhun
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Malaria parasites require certain host nutrients for growth and survival. In this project, we examined the role of the human vitamin biotin in all stages of the malaria life cycle. We cultured blood- and liver-stage malaria parasites in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4eaff528233c57e60dfbee8c267f6ae
https://doi.org/10.1073/pnas.1800717115
https://doi.org/10.1073/pnas.1800717115
Autor:
Jolyn E. Gisselberg, David Bartee, Krista Ann Matthews, Gustavo A. Afanador, Caren L. Freel Meyers, Maroya S. Walters, Sean T. Prigge
Publikováno v:
Molecular Microbiology. 94:156-171
Lipoate scavenging from the human host is essential for malaria parasite survival. Scavenged lipoate is covalently attached to three parasite proteins: the H-protein and the E2 subunits of branched chain amino acid dehydrogenase (BCDH) and α-ketoglu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7c40d72790435a89dd9432c7c720b81
https://doi.org/10.1111/mmi.12753
https://doi.org/10.1111/mmi.12753
Autor:
Christina Deschermeier, David A. Fidock, Sonia Gulati, T. R. Santha Kumar, Brie Falkard, Krista Ann Matthews, Leonie Hecht, Philipp P. Henrich, Sean T. Prigge, Photini Sinnis, Rebecca E. Lewis, Volker Heussler, Micah J. Manary, Elizabeth A. Winzeler
Publikováno v:
Cellular Microbiology. 15:1585-1604
The successful navigation of malaria parasites through their life cycle, which alternates between vertebrate hosts and mosquito vectors, requires a complex interplay of metabolite synthesis and salvage pathways. Using the rodent parasite Plasmodium b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f079316d82f90674fcae22afecba9d78
https://doi.org/10.1111/cmi.12137
https://doi.org/10.1111/cmi.12137
Publikováno v:
Quarterly journal of experimental psychology (2006). 70(7)
Gesture during speech can promote or diminish recall for conversation content. We explored effects of cognitive load on this relationship, manipulating it at two scales: individual-word abstractness and social constraints to prohibit gestures. Prohib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b662fb4e53feb0f9f22fde0cf9bc8a4
https://pubmed.ncbi.nlm.nih.gov/27871207
https://pubmed.ncbi.nlm.nih.gov/27871207
Publikováno v:
Traffic. 12:1124-1138
Trafficking of soluble proteins to the apicoplast in Plasmodium falciparum is determined by an N-terminal transit peptide (TP) which is necessary and sufficient for apicoplast import. Apicoplast precursor proteins are synthesized at the rough endopla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::225661f29f52cc75b74ffd59ec50c4d2
https://doi.org/10.1111/j.1600-0854.2011.01232.x
https://doi.org/10.1111/j.1600-0854.2011.01232.x
Publikováno v:
Genetics. 185:189-198
The escort factor Scap is essential in mammalian cells for regulated activation of sterol regulatory element binding proteins (SREBPs). SREBPs are membrane-bound transcription factors. Cells lacking Scap cannot activate SREBP. They are therefore defi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::797afec9cb36570f6b6fbb37e99fe1bd
https://doi.org/10.1534/genetics.110.114975
https://doi.org/10.1534/genetics.110.114975