Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Krista, Fowles"'
Autor:
Molly K. Grun, Praveen Honhar, Yazhe Wang, Samantha Rossano, Minsoo Khang, Hee Won Suh, Krista Fowles, Harvey J. Kliman, Alessandra Cavaliere, Richard E. Carson, Bernadette Marquez‐Nostra, W. Mark Saltzman
Publikováno v:
Bioengineering & Translational Medicine, Vol 9, Iss 5, Pp n/a-n/a (2024)
Abstract Long‐lasting vaginal dosage forms could improve the therapeutic efficacy of vaginal microbicides, but achieving long‐term delivery to the vaginal canal has been a significant challenge. To advance understanding of vaginal dosage retentio
Externí odkaz:
https://doaj.org/article/b589bf4c529e4236869af6ce392d93fa
Publikováno v:
Chronic Stress, Vol 7 (2023)
Background Females are twice as likely to experience post-traumatic stress disorder (PTSD) than males, yet specific factors contributing to this greater risk are not fully understood. Our clinical and recent preclinical findings suggest a role for th
Externí odkaz:
https://doaj.org/article/93a2b5d5bbf44dfbb2d561a4e171605d
Autor:
Baosheng Chen, Devi Prasan Ojha, Takuya Toyonaga, Jie Tong, Richard Pracitto, Monique A. Thomas, Michael Liu, Michael Kapinos, Li Zhang, Ming-Qiang Zheng, Daniel Holden, Krista Fowles, Jim Ropchan, Nabeel Nabulsi, Henk De Feyter, Richard E. Carson, Yiyun Huang, Zhengxin Cai
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 50:2081-2099
Purpose Currently, there are multiple active clinical trials involving poly(ADP-ribose) polymerase (PARP) inhibitors in the treatment of glioblastoma. The noninvasive quantification of baseline PARP expression using positron emission tomography (PET)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d86caad2c465c980d724d9b1efefe395
https://doi.org/10.1007/s00259-023-06162-y
https://doi.org/10.1007/s00259-023-06162-y
Autor:
Ruth H. Asch, Santosh Pothula, Takuya Toyonaga, Krista Fowles, Stephanie M. Groman, Rolando Garcia-Milian, Ralph J. DiLeone, Jane R. Taylor, Irina Esterlis
Publikováno v:
Neuropsychopharmacology. 48:489-497
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d961744a1768016a021a3e843ce29a12
https://doi.org/10.1038/s41386-022-01441-y
https://doi.org/10.1038/s41386-022-01441-y
Autor:
Ansel T. Hillmer, Daniel Holden, Krista Fowles, Nabeel Nabulsi, Brian L. West, Richard E. Carson, Kelly P. Cosgrove
Publikováno v:
EJNMMI Research, Vol 7, Iss 1, Pp 1-5 (2017)
Abstract Background The 18-kDa translocator protein (TSPO) is an important target for assessing neuroimmune function in brain with positron-emission tomography (PET) imaging. The goal of this work was to assess two [11C]PBR28 imaging paradigms for me
Externí odkaz:
https://doaj.org/article/af9924aaf20a4a3cb598404a9e455730
Autor:
Sophie E. Holmes, Sjoerd J. Finnema, Mika Naganawa, Nicole DellaGioia, Daniel Holden, Krista Fowles, Margaret Davis, Jim Ropchan, Paul Emory, Yunpeng Ye, Nabeel Nabulsi, David Matuskey, Gustavo A. Angarita, Robert H. Pietrzak, Ronald S. Duman, Gerard Sanacora, John H. Krystal, Richard E. Carson, Irina Esterlis
Publikováno v:
Molecular Psychiatry. 27:2273-2281
The discovery of ketamine as a rapid and robust antidepressant marks the beginning of a new era in the treatment of psychiatric disorders. Ketamine is thought to produce rapid and sustained antidepressant effects through restoration of lost synaptic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13faffea66e19bea1bc9f3fe46e66ed2
https://doi.org/10.1038/s41380-022-01465-2
https://doi.org/10.1038/s41380-022-01465-2
Autor:
Hanyi Fang, Samantha Rossano, Xingxing Wang, Nabeel Nabulsi, Brian Kelley, Krista Fowles, Jim Ropchan, Stephen M. Strittmatter, Richard E. Carson, Yiyun Huang
Publikováno v:
Molecular Imaging and Biology. 24:560-569
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec97e8ffa50390f280994191a7bf521d
https://doi.org/10.1007/s11307-021-01698-7
https://doi.org/10.1007/s11307-021-01698-7
Autor:
Ming-Qiang Zheng, Sjoerd J. Finnema, Richard Pracitto, Zhengxin Cai, Jie Tong, Nabeel Nabulsi, Chao Zheng, Zachary Felchner, Krista Fowles, Yiyun Huang, Marcel Lindemann, Li Zhang, Richard E. Carson, Daniel Holden, Kyle C. Wilcox
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 49:1482-1496
Purpose To quantify the synaptic vesicle glycoprotein 2A (SV2A) changes in the whole central nervous system (CNS) under pathophysiological conditions, a high affinity SV2A PET radiotracer with improved in vivo stability is desirable to minimize the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b08fa04c1cd473fe5caef6b7a1359ae
https://doi.org/10.1007/s00259-021-05597-5
https://doi.org/10.1007/s00259-021-05597-5
Autor:
Cristian Constantinescu, David Alagille, Caroline Papin, Eiji Sunahara, Shuhei Ikeda, Tatsuki Koike, Maki Miyamoto, John Seibyl, Gilles Tamagnan, Olivier Barret, Thomas J. Morley, Krista Fowles, Patricia E. Cole, Takanobu Kuroita, Toshiya Nishi
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 49:1148-1156
Purpose Cholesterol 24-hydroxylase (CH24H) is a brain-specific enzyme that plays a major role in brain cholesterol homeostasis by converting cholesterol into 24S-hydroxycholesterol. The selective CH24H inhibitor soticlestat (TAK-935) is being pursued
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c3b49ad503abe1c9b276111d06b8346
https://doi.org/10.1007/s00259-021-05565-z
https://doi.org/10.1007/s00259-021-05565-z
Autor:
Samantha Rossano, Takuya Toyonaga, Eric Berg, Isabella Lorence, Krista Fowles, Nabeel Nabulsi, Jim Ropchan, Songye Li, Yunpeng Ye, Zachary Felchner, David Kukis, Yiyun Huang, Helene Benveniste, Alice F. Tarantal, Stephanie Groman, Richard E. Carson
Publikováno v:
European journal of nuclear medicine and molecular imaging, vol 49, iss 11
Eur J Nucl Med Mol Imaging
Eur J Nucl Med Mol Imaging
PURPOSE: Exploring synaptic density changes during brain growth is crucial to understanding brain development. Previous studies in nonhuman primates report a rapid increase in synapse number between the late gestational period and the early neonatal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a04724910687e2903389725172c6605
https://escholarship.org/uc/item/1p2995gf
https://escholarship.org/uc/item/1p2995gf
