Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Krist T. Azizian"'
Autor:
Sriram Vaidyanathan, Krist T. Azizian, A.K.M. Ashiqul Haque, Jordana M. Henderson, Ayal Hendel, Sabrina Shore, Justin S. Antony, Richard I. Hogrefe, Michael S.D. Kormann, Matthew H. Porteus, Anton P. McCaffrey
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 12, Iss , Pp 530-542 (2018)
The Cas9/guide RNA (Cas9/gRNA) system is commonly used for genome editing. mRNA expressing Cas9 can induce innate immune responses, reducing Cas9 expression. First-generation Cas9 mRNAs were modified with pseudouridine and 5-methylcytosine to reduce
Externí odkaz:
https://doaj.org/article/9fa5ea5932e04ba7890894069d5b7227
Autor:
Qi Cui, Su Yang, Peng Ye, E. Tian, Guoqiang Sun, Jiehua Zhou, Guihua Sun, Xiaoxuan Liu, Chao Chen, Kiyohito Murai, Chunnian Zhao, Krist T. Azizian, Lu Yang, Charles Warden, Xiwei Wu, Massimo D'Apuzzo, Christine Brown, Behnam Badie, Ling Peng, Arthur D. Riggs, John J. Rossi, Yanhong Shi
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
TLX is a nuclear receptor essential for neural stem cell self-renewal and recently involved in glioblastoma development. In this study, the authors show that inhibition of TLX expression, achieved using a dendrimer nanovector-delivered siRNAs or vira
Externí odkaz:
https://doaj.org/article/1442e58753a245f1a93ab4dce27c8c5f
Autor:
A. K. M. Ashiqul Haque, Matthew H. Porteus, Krist T. Azizian, Sriram Vaidyanathan, Anton P. McCaffrey, Sabrina Shore, Michael S. D. Kormann, Ayal Hendel, Richard I. Hogrefe, Jordana M. Henderson, Justin S. Antony
Publikováno v:
Molecular Therapy. Nucleic Acids
Molecular Therapy-Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 12, Iss, Pp 530-542 (2018)
Molecular Therapy-Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 12, Iss, Pp 530-542 (2018)
The Cas9/guide RNA (Cas9/gRNA) system is commonly used for genome editing. mRNA expressing Cas9 can induce innate immune responses, reducing Cas9 expression. First-generation Cas9 mRNAs were modified with pseudouridine and 5-methylcytosine to reduce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51010ec6a713bfa68fb7ca7248c7c0a0
https://pubmed.ncbi.nlm.nih.gov/30195789
https://pubmed.ncbi.nlm.nih.gov/30195789
Autor:
Massimo D'Apuzzo, Lu Yang, Christine E. Brown, Ling Peng, Xiaoxuan Liu, Chao Chen, Charles Warden, Qi Cui, John J. Rossi, Xiwei Wu, Peng Ye, Chunnian Zhao, Guoqiang Sun, Yanhong Shi, Kiyohito Murai, Arthur D. Riggs, Guihua Sun, Su Yang, Krist T. Azizian, E Tian, Jiehua Zhou, Behnam Badie
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2016, 7, pp.10637. ⟨10.1038/ncomms10637⟩
Nature Communications, 2016, 7, pp.10637. ⟨10.1038/ncomms10637⟩
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Nature Communications, Nature Publishing Group, 2016, 7, pp.10637. ⟨10.1038/ncomms10637⟩
Nature Communications, 2016, 7, pp.10637. ⟨10.1038/ncomms10637⟩
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Glioblastomas have been proposed to be maintained by highly tumorigenic glioblastoma stem cells (GSCs) that are resistant to current therapy. Therefore, targeting GSCs is critical for developing effective therapies for glioblastoma. In this study, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be5cf978eaa0edfe08c23bacc485ca8f
https://pubmed.ncbi.nlm.nih.gov/26838672
https://pubmed.ncbi.nlm.nih.gov/26838672
Autor:
Martin S. Denzel, Barbara Ranscht, Edward Monosov, Fred Levine, Philip D.G. Miles, Björn Tyrberg, Krist T. Azizian, Maria L. Nieves
Publikováno v:
Islets
Glucose homeostasis depends on adequate control of insulin secretion. We report the association of the cell-adhesion and adiponectin (APN)-binding glycoprotein T-cadherin (Cdh13) with insulin granules in mouse and human beta-cells. Immunohistochemist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6450a560c6a881600923beeb8787b122
https://hdl.handle.net/21.11116/0000-000B-6DD8-8
https://hdl.handle.net/21.11116/0000-000B-6DD8-8
Autor:
Joel Jessee, Julie R. Escamilla-Powers, Brea Midthune, Anton P. McCaffrey, Alexandre Lebedev, Dongwon Shin, Richard I. Hogrefe, Hiroko Yokoe, Krist T. Azizian
Publikováno v:
Molecular Therapy. 23:S259
Recently, there has been significant interest in the use of messenger RNA (mRNA) based expression systems for gene therapy applications. Several groups have shown that mRNA is an attractive vehicle for therapeutic gene expression in mammals (Kormann
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbd957654aff7448e650cefe76d8c451
https://doi.org/10.1016/s1525-0016(16)34260-5
https://doi.org/10.1016/s1525-0016(16)34260-5