Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kristína Krochtová"'
Autor:
Terézia Hudáková, Martina Šemeláková, Peter Očenáš, Mária Kožurková, Kristína Krochtová, Simona Sovová, Zuzana Tóthová, Zuzana Guľášová, Peter Popelka, Peter Solár
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract DNA topoisomerases regulate conformational changes in DNA topology during normal cell growth, such as replication, transcription, recombination, and repair, and may be targeted for anticancer drugs. A DNA topology assay was used to investiga
Externí odkaz:
https://doaj.org/article/1912b47f60754379b54fb7b761c8a955
Autor:
Kristína Krochtová, Annamária Halečková, Ladislav Janovec, Michaela Blizniaková, Katarína Kušnírová, Mária Kožurková
Publikováno v:
Molecules, Vol 28, Iss 3, p 1308 (2023)
A series of novel 3,9-disubstituted acridines were synthesized and their biological potential was investigated. The synthetic plan consists of eight reaction steps, which produce the final products, derivatives 17a–17j, in a moderate yield. The pri
Externí odkaz:
https://doaj.org/article/ed47edae55b74380a01eb11228659260
Autor:
Terézia HUDÁKOVÁ, Martina ŠEMELÁKOVÁ, Peter OČENÁŠ, Mária KOŽURKOVÁ, Kristína KROCHTOVÁ, Simona SOVOVÁ, Zuzana TÓTHOVÁ, Zuzana GUĽÁŠOVÁ, Peter POPELKA, Peter SOLÁR
This study aimed to explain the effect of extracts from chili pepper varieties containing capsaicin and dihydrocapsaicin, among other substances, on the growth of colon cancer in humans through therapeutic research and drug screening. DNA topoisomera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3c3cee51bd6ab3e75927027d42f1494
https://doi.org/10.21203/rs.3.rs-2817868/v1
https://doi.org/10.21203/rs.3.rs-2817868/v1
Publikováno v:
Tetrahedron. 120:132898
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02b47ea5a12e58472e596ce046f12034
https://doi.org/10.1016/j.tet.2022.132898
https://doi.org/10.1016/j.tet.2022.132898
Publikováno v:
Journal of Fluorine Chemistry. 250:109879
We report herein the synthesis of a small 28-membered library of novel 5-fluorinated indole phytoalexins. Target compounds were designed by a structure-based bioisosterism strategy. The newly prepared compounds were screened in vitro for cytotoxic ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3126fddcef2253b430499ccb11c29a69
https://doi.org/10.1016/j.jfluchem.2021.109879
https://doi.org/10.1016/j.jfluchem.2021.109879