Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Krislyn P. Porter"'
Publikováno v:
Current Research in Immunology, Vol 2, Iss , Pp 52-59 (2021)
Due to potential severity of disease caused by SARS-CoV-2 infection, it is critical to understand both mechanisms of viral pathogenesis as well as diversity of host responses to infection. Reduced A-to-I editing of endogenous double-stranded RNAs (ds
Externí odkaz:
https://doaj.org/article/99bdb7239733469e9ba3ce5531eb37e3
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Alu retrotransposons belong to the class of short interspersed nuclear elements (SINEs). Alu RNA is abundant in cells and its repetitive structure forms double-stranded RNAs (dsRNA) that activate dsRNA sensors and trigger innate immune responses with
Externí odkaz:
https://doaj.org/article/cba9c00726d949239c293db01b634cd7
Publikováno v:
Brain Communications. 4
Alzheimer’s disease is the most common form of dementia and recent studies identify a type 1 interferon response in Alzheimer’s disease possibly driving neuro-inflammation and other Alzheimer’s disease pathologies. Loss of adenosine-to-inosine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff89f19071a0b3310dd97410da59b5bf
https://doi.org/10.1093/braincomms/fcac238
https://doi.org/10.1093/braincomms/fcac238
Publikováno v:
Current Research in Immunology
Due to potential severity of disease caused by SARS-CoV-2 infection, it is critical to understand both mechanisms of viral pathogenesis as well as diversity of host responses to infection. Reduced A-to-I editing of endogenous double-stranded RNAs (ds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd98324ec3c7ed18191a0ff53fab455c
https://pubmed.ncbi.nlm.nih.gov/33969287
https://pubmed.ncbi.nlm.nih.gov/33969287
Cutting Edge: Reduced Adenosine-to-Inosine Editing of Endogenous Alu RNAs in Severe COVID-19 Disease
Publikováno v:
J Immunol
Severe COVID-19 disease is associated with elevated inflammatory responses. One form of Aicardi–Goutières syndrome caused by inactivating mutations in ADAR results in reduced adenosine-to-inosine (A-to-I) editing of endogenous dsRNAs, induction of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dcc2cd7ad37074b409201f2a68e0ba4
https://pubmed.ncbi.nlm.nih.gov/33782089
https://pubmed.ncbi.nlm.nih.gov/33782089