Zobrazeno 1 - 10
of 288
pro vyhledávání: '"Krishnendu Roy"'
Autor:
Anne L. Plant, Nicole Piscopo, Krishanu Saha, Claudia Zylberberg, Krishnendu Roy, Katherine Tsokas, Samantha N. Schumm, Sarah H. Beachy
Publikováno v:
npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-6 (2022)
Applying Systems Thinking to Regenerative Medicine—A Workshop was organized by the National Academies of Sciences, Engineering, and Medicine’s Forum on Regenerative Medicine. The meeting brought together leaders from government, academia, industr
Externí odkaz:
https://doaj.org/article/c973c93c4a25491fa3c880151596dec5
Autor:
Jia Yao, Svetlana Atasheva, Randall Toy, Emmeline L. Blanchard, Philip J. Santangelo, Krishnendu Roy, Edward S. Mocarski, Dmitry M. Shayakhmetov
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Pathogens trigger activation of sensors of the innate immune system that initiate molecular signaling enabling appropriate host defense programs. Although recognition of pathogen-specific moieties or PAMPs by specialized receptors of the imm
Externí odkaz:
https://doaj.org/article/82c6fbda93044ded80e53e06e8ddf1db
Autor:
Annie C. Bowles-Welch, Angela C. Jimenez, Hazel Y. Stevens, David A. Frey Rubio, Linda E. Kippner, Carolyn Yeago, Krishnendu Roy
Publikováno v:
Bone Reports, Vol 18, Iss , Pp 101656- (2023)
Bone is a complex tissue capable of natural repair to injury, however, the healing process is often impaired by the untoward effects of trauma, defects, and disease. Thus, therapeutic modalities, including the use of cells involved in the body's natu
Externí odkaz:
https://doaj.org/article/f9a8f6c1ab4e4176b2ba850e5238c3c2
Autor:
Camila Medrano-Trochez, Paramita Chatterjee, Pallab Pradhan, Hazel Y. Stevens, Molly E. Ogle, Edward A. Botchwey, Joanne Kurtzberg, Carolyn Yeago, Greg Gibson, Krishnendu Roy
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-14 (2021)
Abstract Background Human Mesenchymal stromal cells (hMSCs) from various tissue sources are widely investigated in clinical trials. These MSCs are often administered to patients immediately after thawing the cryopreserved product (out-of-thaw), yet l
Externí odkaz:
https://doaj.org/article/6fea1886cd2e42f6a0a90995bb79307f
Autor:
Casey E. Vantucci, Tyler Guyer, Kelly Leguineche, Paramita Chatterjee, Angela Lin, Kylie E. Nash, Molly Ann Hastings, Travis Fulton, Clinton T. Smith, Drishti Maniar, David A. Frey Rubio, Kaya Peterson, Julia Andraca Harrer, Nick J. Willett, Krishnendu Roy, Robert E. Guldberg
Publikováno v:
Frontiers in Surgery, Vol 9 (2022)
Bone non-unions resulting from severe traumatic injuries pose significant clinical challenges, and the biological factors that drive progression towards and healing from these injuries are still not well understood. Recently, a dysregulated systemic
Externí odkaz:
https://doaj.org/article/858170e428e04cdbbb4aa8cf6bbc328d
Autor:
Liana Kramer, Hannah W. Song, Kaiya Mitchell, Mythili Kartik, Ritika Jain, Victoria Lozano Escarra, Enrique Quiros, Harrison Fu, Ankur Singh, Krishnendu Roy
Publikováno v:
Advanced NanoBiomed Research, Vol 2, Iss 7, Pp n/a-n/a (2022)
High‐affinity antigen‐specific B cells are generated within specialized structures, germinal centers (GCs), inside lymphoid organs. In GCs, follicular dendritic cells (FDCs) present antigens on their membrane surface to cognate B cells, inducing
Externí odkaz:
https://doaj.org/article/2dc50b9144d549ed9b1af37998085adf
Autor:
Valerie Y. Odeh‐Couvertier, Nathan J. Dwarshuis, Maxwell B. Colonna, Bruce L. Levine, Arthur S. Edison, Theresa Kotanchek, Krishnendu Roy, Wandaliz Torres‐Garcia
Publikováno v:
Bioengineering & Translational Medicine, Vol 7, Iss 2, Pp n/a-n/a (2022)
Abstract Large‐scale, reproducible manufacturing of therapeutic cells with consistently high quality is vital for translation to clinically effective and widely accessible cell therapies. However, the biological and logistical complexity of manufac
Externí odkaz:
https://doaj.org/article/5bc5f7736edf445dad237c85b52c5a43
Autor:
Brock Kingstad-Bakke, Randall Toy, Woojong Lee, Pallab Pradhan, Gabriela Vogel, Chandranaik B. Marinaik, Autumn Larsen, Daisy Gates, Tracy Luu, Bhawana Pandey, Yoshihoro Kawaoka, Krishnendu Roy, M. Suresh
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Eliciting durable and protective T cell-mediated immunity in the respiratory mucosa remains a significant challenge. Polylactic-co-glycolic acid (PLGA)-based cationic pathogen-like particles (PLPs) loaded with TLR agonists mimic biophysical propertie
Externí odkaz:
https://doaj.org/article/67c46005f89f4a50b0ee1e1d7965e5bf
Autor:
Woojong Lee, Brock Kingstad-Bakke, Brett Paulson, Autumn Larsen, Katherine Overmyer, Chandranaik B Marinaik, Kelly Dulli, Randall Toy, Gabriela Vogel, Katherine P Mueller, Kelsey Tweed, Alex J Walsh, Jason Russell, Krishanu Saha, Leticia Reyes, Melissa C Skala, John-Demian Sauer, Dmitry M Shayakhmetov, Joshua Coon, Krishnendu Roy, M Suresh
Publikováno v:
PLoS Pathogens, Vol 17, Iss 1, p e1009168 (2021)
There is a critical need for adjuvants that can safely elicit potent and durable T cell-based immunity to intracellular pathogens. Here, we report that parenteral vaccination with a carbomer-based adjuvant, Adjuplex (ADJ), stimulated robust CD8 T-cel
Externí odkaz:
https://doaj.org/article/73580a7e1e6e47af817c8a1751850e37
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Mesenchymal stromal cells (MSCs) have been widely investigated for regenerative medicine applications, from treating various inflammatory diseases as a cell therapy to generating engineered tissue constructs. Numerous studies have evaluated the poten
Externí odkaz:
https://doaj.org/article/67bc1f101a224a8ea5f150efaed3566c