Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Krishnananda Samanta"'
Autor:
Poulami Jana, Krishnananda Samanta, Martin Ehlers, Elio Zellermann, Sandra Bäcker, Roland H. Stauber, Carsten Schmuck, Shirley K. Knauer
Publikováno v:
ChemBioChem. 24
We rationally designed a series of amphiphilic hepta-peptides enriched with a chemically conjugated guanidiniocarbonylpyrrole (GCP) unit at the lysine side chain. All peptides are composed of polar (GCP) and non-polar (cyclohexyl alanine) residues bu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::797812c1677b91eef85091cc1294ba93
https://doi.org/10.1002/cbic.202200519
https://doi.org/10.1002/cbic.202200519
Autor:
Priyanka Singh, Krishnananda Samanta, Ndeye Mathy Kebe, Grégory Michel, Baptiste Legrand, Vera E. Sitnikova, Andrey V. Kajava, Michel Pagès, Patrick Bastien, Christelle Pomares, Olivier Coux, Jean-François Hernandez
Publikováno v:
Bioorganic Chemistry
Bioorganic Chemistry, 2022, 119, pp.105539. ⟨10.1016/j.bioorg.2021.105539⟩
Bioorganic Chemistry, 2022, 119, pp.105539. ⟨10.1016/j.bioorg.2021.105539⟩
International audience; It is urgent to develop less toxic and more efficient treatments for leishmaniases and trypanosomiases. We explore the possibility to target the parasite mitochondrial HslVU protease, which is essential for growth and has no a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11dde9a36b257da78f9dea965b5ed607
https://pubmed.ncbi.nlm.nih.gov/34894575
https://pubmed.ncbi.nlm.nih.gov/34894575
Publikováno v:
European Journal of Organic Chemistry. 2018:6515-6518
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97191c7737d7deda431d15df9551e711
https://doi.org/10.1002/ejoc.201801210
https://doi.org/10.1002/ejoc.201801210
Autor:
Shirley K. Knauer, Poulami Jana, Krishnananda Samanta, Sandra Bäcker, Elio Zellermann, Carsten Schmuck
Publikováno v:
Angewandte Chemie. 129:8195-8200
The effect of citrate-stabilized gold nanoparticles (AuNPs) on the secondary structure of an artificial β-sheet-forming cationic peptide has been studied. The AuNPs inhibited β-sheet formation and led to fragmented fibrils and spherical oligomers w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e36e3f47d03730faf37f3e31fb659c9
https://doi.org/10.1002/ange.201700713
https://doi.org/10.1002/ange.201700713
Publikováno v:
Tetrahedron. 73:1911-2008
Enantiomerically pure α-amino acids (α-AAs) are, for a long time, considered as a major class of chiral pools. Their employment in the enantioselective synthesis of natural products has made enormous impact in the general organic synthesis. This re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7392c4c7a375a6c37830fc15fe50aa84
https://doi.org/10.1016/j.tet.2017.02.029
https://doi.org/10.1016/j.tet.2017.02.029
Publikováno v:
Soft Matter. 13:8108-8112
A host-guest interaction between a multi-cationic dendrimer 1 functionalized with 16 guanidiniocarbonyl pyrrole (GCP) groups on its surface and naphthalene diimide dicarboxylic acid (NDIDC) in a 1 : 8 ratio leads to the formation of a new type of inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d7ebad4dd658e229e59f28d20047452
https://doi.org/10.1039/c7sm01641g
https://doi.org/10.1039/c7sm01641g
Publikováno v:
Angewandte Chemie. 128:15513-15517
The new amphiphilic peptide 1 is composed of alternating cyclohexyl side chains and guanidiniocarbonyl pyrrole (GCP) groups. In contrast to analogue 2, which contains lysine instead of the GCP groups and only exists as a random coil owing to charge r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b4f2ea253ee596faa4efddc0abe1e50
https://doi.org/10.1002/ange.201608069
https://doi.org/10.1002/ange.201608069
Publikováno v:
Chemical Communications. 52:12446-12449
A novel hybrid compound 1 efficiently shuttles genetic material into HeLa cells at concentrations as low as 0.6 μM, whereas the parent compound PAMAM-G2 is ineffective even at 200 μM. The high efficiency of 1 stems from its capabiliy to form highly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0374fde7e97279106eb78412088928fb
https://doi.org/10.1039/c6cc06404c
https://doi.org/10.1039/c6cc06404c
Rational design of synthetic molecules with the aim of inhibiting protein–protein interactions (PPIs) that are key players in human diseases and biology, opens a new perspective in drug discovery. Here we describe synthetic molecules including α-h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a4ae0d93ea46dcbb387368e17f59417
https://doi.org/10.1016/b978-0-12-409547-2.12533-8
https://doi.org/10.1016/b978-0-12-409547-2.12533-8
Autor:
Carsten Schmuck, Krishnananda Samanta
Publikováno v:
Chemical Communications. 51:16065-16067
A guanidiniocarbonyl pyrrole (GCP) cation forms stable H-bond assisted ion pairs with carboxylates even in aqueous solutions. A tetra GCP cation 1 undergoes efficient two-component self-assembly with Na4EDTA, a tetra-carboxylate, leading to 3D supram
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f17f8fb01cbccd0fe5a55309d746686a
https://doi.org/10.1039/c5cc06392b
https://doi.org/10.1039/c5cc06392b