Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Krishnan K. Mahadevan"'
Autor:
Krishnan K. Mahadevan, Kathleen M. McAndrews, Valerie S. LeBleu, Sujuan Yang, Hengyu Lyu, Bingrui Li, Amari M. Sockwell, Michelle L. Kirtley, Sami J. Morse, Barbara A. Moreno Diaz, Michael P. Kim, Ningping Feng, Anastasia M. Lopez, Paola A. Guerrero, Hikaru Sugimoto, Kent A. Arian, Haoqiang Ying, Yasaman Barekatain, Patience J. Kelly, Anirban Maitra, Timothy P. Heffernan, Raghu Kalluri
Publikováno v:
bioRxiv
Pancreatic ductal adenocarcinoma (PDAC) is associated with mutations in Kras, a known oncogenic driver of PDAC; and theKRASG12Dmutation is present in nearly half of PDAC patients. Recently, a non-covalent small molecule inhibitor (MRTX1133) was ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05ea79611c3fdc6d33522b958197d67c
https://doi.org/10.1101/2023.02.15.528757
https://doi.org/10.1101/2023.02.15.528757
Autor:
Subhiksha Raghuram, Yuri Mackeyev, Jessica Symons, Yasmin Zahra, Valeria Gonzalez, Krishnan K. Mahadevan, Katherinne I. Requejo, Anton Liopo, Paul Derry, Eugene Zubarev, Onur Sahin, Joseph Byung-Kyu Kim, Pankaj K. Singh, Sang Hyun Cho, Sunil Krishnan
Publikováno v:
Biomaterials. 291
Major impediments to conveyance of intravenously administered drugs to tumors are biofouling, opsonization, and rapid clearance from the circulation by macrophages and reticuloendothelial phagocytes. Cloaking nanoparticles with stealth epilayers part
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a2bb68bacb0bdec226379cf8103dc8d
https://pubmed.ncbi.nlm.nih.gov/36368139
https://pubmed.ncbi.nlm.nih.gov/36368139
Autor:
Andrew L. Warshaw, Carlos Fernandez-del Castillo, Keith D. Lillemoe, Soldano Ferrone, Jennifer A. Wargo, Vincenzo Villani, Krishnan K. Mahadevan, Matteo Ligorio, Irene Y. Zhang, Mark Vangel, Vikram Deshpande, Cristina R. Ferrone, Francesco Sabbatino, David T. Ting
Publikováno v:
Ann Surg Oncol
BACKGROUND. The staging of pancreatic neuroendocrine tumors (PNETs) is continuously evolving. Mitotic count, as measured by hematoxylin and eosin (H&E) or Ki67 labeling index (Ki67LI), is the best predictor of disease biology. However, both of these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c6ed0db4f69c14c6a78c068e684d7d5
https://doi.org/10.1245/s10434-016-5171-x
https://doi.org/10.1245/s10434-016-5171-x
Publikováno v:
Histopathology. 68:968-976
Aims To explore the utility of an IgG4 immunohistochemical stain to help distinguish eosinophilic oesophagitis from gastroesophageal reflux disease. Methods and results We examined 21 cases of eosinophilic oesophagitis and 25 cases of gastroesophagea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee373add57b00788f62c3747dc63d5e8
https://doi.org/10.1111/his.12892
https://doi.org/10.1111/his.12892
Autor:
Linda T. Nieman, William R. Jeck, Manish Gala, Azfar Neyaz, Krishnan K. Mahadevan, Martin S. Taylor, Jacob R. Bledsoe, Ömer H. Yilmaz, Vikram Deshpande, Steffen Rickelt, Robert D. Odze, Deepa T. Patil, Kshitij S. Arora, David T. Ting, Miguel Rivera
Publikováno v:
Clinical and Translational Gastroenterology
INTRODUCTION: The expression of LGR5, a known stem cell marker, is poorly understood in Barrett's esophagus (BE) and related neoplasia. The aim of this study was to evaluate LGR5 in BE and related neoplasia and to evaluate its utility as a potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d0bab9b690efc1432ebb392ade4ff0a
https://doi.org/10.14309/ctg.0000000000000272
https://doi.org/10.14309/ctg.0000000000000272
Autor:
Anupriya S. Kulkarni, Erik A. Williams, Carlos Fernandez-del Castillo, Theodore S. Hong, Nabeel Bardeesy, Kshitij S. Arora, Vikram Deshpande, Keith D. Lillemoe, Arnaud Amzallag, Krishnan K. Mahadevan, David T. Ting, Cristina R. Ferrone
Publikováno v:
Mod Pathol
Metastasis following surgical resection is a leading cause of mortality in pancreatic ductal adenocarcinoma. Epithelial-mesenchymal transition is thought to play an important role in metastasis, although its clinical relevance in metastasis remains u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89c4540a14c00cb2609b236d9685ceb9
https://pubmed.ncbi.nlm.nih.gov/30683911
https://pubmed.ncbi.nlm.nih.gov/30683911
Autor:
Jason L. Hornick, Miguel Rivera, Vikram Deshpande, Krishnan K. Mahadevan, Jeffrey F. Krane, Darcy A. Kerr, William C. Faquin, Kshitij S. Arora, David T. Ting
Publikováno v:
American Journal of Surgical Pathology. 39:1643-1652
High-risk human papillomavirus (HR-HPV) is a major etiologic agent in a subset of head and neck squamous cell carcinomas (HNSCCs), and its recognition has prognostic and predictive implications. The availability of a sensitive and specific test to as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eec207091759d5f8060a713d86d727c
https://doi.org/10.1097/pas.0000000000000516
https://doi.org/10.1097/pas.0000000000000516
Publikováno v:
Journal of Clinical and Diagnostic Research, Vol 8, Iss 5, Pp FC04-FC07 (2014)
Backgorund: Angiogenesis is associated with growth, dissemination and metastasis of tumours. Measurement of Microvascular Density (MVD) is a quantitative method of assessment of angiogenesis and would give a proportional co relate of the angiogenic p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::272aa5db9e71658d690db7a4b2ddafcf
https://doi.org/10.7860/jcdr/2014/7994.4405
https://doi.org/10.7860/jcdr/2014/7994.4405
Autor:
Zukerberg L; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Mahadevan K; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Selig M; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Deshpande V; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Publikováno v:
Histopathology [Histopathology] 2016 Jun; Vol. 68 (7), pp. 968-76. Date of Electronic Publication: 2016 Jan 21.