Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Krishnamurthy, Malathi"'
Autor:
Barkha Ramnani, Shelby Powell, Adarsh G. Shetty, Praveen Manivannan, Brian R. Hibbard, Douglas W. Leaman, Krishnamurthy Malathi
Publikováno v:
Viruses, Vol 15, Iss 2, p 466 (2023)
Virus infection activates integrated stress response (ISR) and stress granule (SG) formation and viruses counteract by interfering with SG assembly, suggesting an important role in antiviral defense. The infection of fish cells by Viral Hemorrhagic S
Externí odkaz:
https://doaj.org/article/068c963a9e8742ecbe74c5ba522d0bbf
Autor:
Xiaolu Zhang, Mahmoud Ali Eladawi, William George Ryan, Xiaoming Fan, Stephen Prevoznik, Trupti Devale, Barkha Ramnani, Krishnamurthy Malathi, Etienne Sibille, Robert Mccullumsmith, Toshifumi Tomoda, Rammohan Shukla
The underlying biological mechanisms that contribute to the heterogeneity of major depressive disorder (MDD) presentation remain poorly understood, highlighting the need for a conceptual framework that can explain this variability and bridge the gap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c08b5ff1661c7d9496f65b24c5ea1d6
https://doi.org/10.1101/2023.05.04.539419
https://doi.org/10.1101/2023.05.04.539419
Publikováno v:
Viruses, Vol 13, Iss 2, p 315 (2021)
Host response to a viral infection includes the production of type I interferon (IFN) and the induction of interferon-stimulated genes that have broad antiviral effects. One of the key antiviral effectors is the IFN-inducible oligoadenylate synthetas
Externí odkaz:
https://doaj.org/article/f60ca9f2cf78448d98f3e64fc3781d46
Autor:
Shelby Powell Kesterson, Jeffery Ringiesn, Vikram N. Vakharia, Brian S. Shepherd, Douglas W. Leaman, Krishnamurthy Malathi
Publikováno v:
Viruses, Vol 12, Iss 5, p 499 (2020)
Viral hemorrhagic septicemia virus (VHSV) is one of the most deadly infectious fish pathogens, posing a serious threat to the aquaculture industry and freshwater ecosystems worldwide. Previous work showed that VHSV sub-genotype IVb suppresses host in
Externí odkaz:
https://doaj.org/article/6b5aae960087487bb4359b45eb520192
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 8, Pp 17611-17636 (2015)
Autophagy and apoptosis share regulatory molecules enabling crosstalk in pathways that affect cellular homeostasis including response to viral infections and survival of tumor cells. Ribonuclease L (RNase L) is an antiviral endonuclease that is activ
Externí odkaz:
https://doaj.org/article/8ca112652450437da242e1c72cb37b1b
Autor:
Praveen Manivannan, Vidita Reddy, Sushovita Mukherjee, Kirsten Neytania Clark, Krishnamurthy Malathi
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 14, p 3535 (2019)
Apoptosis of virus-infected cells is an effective antiviral mechanism in addition to interferon induction to establish antiviral state to restrict virus spread. The interferon-inducible 2′−5′ oligoadenylate synthetase/RNase L pathway results in
Externí odkaz:
https://doaj.org/article/133e829e98684c8896331397dd3e3164
Autor:
Krishnamurthy Malathi, Mohammad Adnan Siddiqui, Shubham Dayal, Merna Naji, Heather J. Ezelle, Chun Zeng, Aimin Zhou, Bret A. Hassel
Publikováno v:
mBio, Vol 5, Iss 6 (2014)
ABSTRACT The actin cytoskeleton and its network of associated proteins constitute a physical barrier that viruses must circumvent to gain entry into cells for productive infection. The mechanisms by which the physical signals of infection are sensed
Externí odkaz:
https://doaj.org/article/83b76e73f0084d90a5f089dc2009b7cb
Autor:
Shubham Dayal, Jun Zhou, Praveen Manivannan, Mohammad Adnan Siddiqui, Omaima Farid Ahmad, Matthew Clark, Sahezeel Awadia, Rafael Garcia-Mata, Lirim Shemshedini, Krishnamurthy Malathi
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 3, p 529 (2017)
The interferon antiviral pathways and prostate cancer genetics converge on a regulated endoribonuclease, RNase L. Positional cloning and linkage studies mapped Hereditary Prostate Cancer 1 (HPC1) to RNASEL. To date, there is no correlation of viral i
Externí odkaz:
https://doaj.org/article/3ca06e7fef2d48918fdec8a992041068
Publikováno v:
Viruses, Vol 13, Iss 315, p 315 (2021)
Viruses
Volume 13
Issue 2
Viruses
Volume 13
Issue 2
Host response to a viral infection includes the production of type I interferon (IFN) and the induction of interferon-stimulated genes that have broad antiviral effects. One of the key antiviral effectors is the IFN-inducible oligoadenylate synthetas
Publikováno v:
International Journal of Molecular Sciences, Vol 17, Iss 1, p 74 (2016)
The interferon (IFN)-regulated endoribonuclease RNase-L is involved in multiple aspects of the antimicrobial innate immune response. It is the terminal component of an RNA cleavage pathway in which dsRNA induces the production of RNase-L-activating 2
Externí odkaz:
https://doaj.org/article/376fc65c88ef45bea1c65947df558f24