Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Krishnakumar N. Menon"'
Autor:
Ragima Nadesh, Krishnakumar N. Menon, Lalitha Biswas, Ullas Mony, K. Subramania Iyer, Sundeep Vijayaraghavan, Ajit Nambiar, Shantikumar Nair
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/52f79214a65044c0946279935ea29c74
Autor:
Tessy Xavier, Lakshmi Sumitra Vijayachandran, Rumamol Chandran, Ullas Mony, Anitha Augustine, Neeraj Sidharthan, Rema Ganapathy, Pavithran Keechilat, K R. Sundaram, Krishnakumar N. Menon
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract We report here the identification and validation of prefoldin 5-alpha (PFDN5-α) for the first time as prognostic biomarker for prediction of central nervous system (CNS) leukemia of B cell acute lymphoblastic leukemia (B-ALL) origin. Since
Externí odkaz:
https://doaj.org/article/fa368577a47f4f7c852c3a41d28c1c5d
Autor:
Ragima Nadesh, Krishnakumar N. Menon, Lalitha Biswas, Ullas Mony, K. Subramania Iyer, Sundeep Vijayaraghavan, Ajit Nambiar, Shantikumar Nair
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract In the present study, a protocol was developed for processing of human adipose derived mesenchymal stem cell secretome formulation of varying concentration. Its molecular composition was evaluated, and its effectiveness in vitro using breast
Externí odkaz:
https://doaj.org/article/3aa0dff7803d4242bb5922a9ae6636ca
Publikováno v:
Biomarker Research, Vol 6, Iss 1, Pp 1-6 (2018)
Abstract Background Carcinogenesis is a multistep process which involves interplay between the tumour cells and the matrix proteins. This occurs by adherence between the tumour cells and proteins in the extracellular matrix. VHL mutation affects thro
Externí odkaz:
https://doaj.org/article/64fa32f6e5d949888d718b1c87b1a8de
Autor:
Sunitha Subhramanian, Ajish Ariyath, Reshma Sabhi, Tessy Xavier, Anandkumar Anandakuttan, Sudheeran Kannoth, Arumugam Thennavan, Kannoth Panicker Sreekumar, Ayalur Kodakara Kochugovindan Unni, Chethampadi Gopi Mohan, Krishnakumar N. Menon
Publikováno v:
ACS Chemical Neuroscience. 14:72-86
In the emerging context of gut-brain control of multiple sclerosis (MS), developing therapeutics targeting proinflammatory proteins controlling the gut-brain immunomodulation is welcoming. One such immunomodulator is glia maturation factor-β (GMF-β
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::263449f8f04c1e2e463bf805840c4eee
https://doi.org/10.1021/acschemneuro.2c00472
https://doi.org/10.1021/acschemneuro.2c00472
Publikováno v:
Advanced Pharmaceutical Bulletin. 12:490-508
Schizophrenia is a neuropsychiatric disorder mainly affecting the central nervous system (CNS), presented with auditory and visual hallucinations, delusion and withdrawal from society. Abnormal dopamine levels mainly characterise the disease; various
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d94576a4cb69cc68f5e9750acfda6d92
https://doi.org/10.34172/apb.2022.052
https://doi.org/10.34172/apb.2022.052
Autor:
Neha Saji, Natasha Radhakrishnan, Gopal S Pillai, Krishnakumar N. Menon, Swetha Pallikara, Tessy Xavier
Publikováno v:
Indian Journal of Ophthalmology
Indian Journal of Ophthalmology, Vol 69, Iss 6, Pp 1475-1481 (2021)
Indian Journal of Ophthalmology, Vol 69, Iss 6, Pp 1475-1481 (2021)
Purpose: Identification of nonresponders prior to anti-vascular endothelial growth factor (anti-VEGF) therapy would help in the judicious clinical management of diabetic macular edema (DME) patients. Thus, a systematic study was initiated to identify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4e87b609a661faa3650d87eec78d2fa
http://europepmc.org/articles/PMC8302316
http://europepmc.org/articles/PMC8302316
Autor:
Keechilat Pavithran, Anna Mathew Ambily, Manzoor Koyakutty, Shantikumar V. Nair, Krishnakumar N. Menon, Kottarapat Jeena, Maneesh Manohar, Ranjith Ramachandran, Ashok Pillai, Genekehal Siddaramana Gowd, Koythatta Meethalveedu Sajesh, Cheripelil Abraham Manju
Publikováno v:
Neuro-oncology Advances
BackgroundNanoparticle siRNA-conjugates are promising clinical therapeutics as indicated by recent US-FDA approval. In glioma stem cells (GSC), multiple stemness associated genes were found aberrant. We report intracranially injectable, multi-gene-ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b2b193e2ad62e04c34c6bf46026f1d6
https://pubmed.ncbi.nlm.nih.gov/34604750
https://pubmed.ncbi.nlm.nih.gov/34604750
Autor:
Tessy Xavier, Lakshmi Sumitra Vijayachandran, Ullas Mony, Anitha Augustine, Neeraj Sidharthan, Pavithran Keechilat, K.R Sundaram, Krishnakumar N Menon
BackgroundThe gold standard for central nervous system (CNS) B cell acute lymphoblastic leukemia (B-ALL) diagnosis is cerebrospinal fluid (CSF) cytology with poor sensitivity. Thus, prophylactic intrathecal chemotherapy is implemented, which has seve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a88d8ed8f72d37616a8038be849d835
https://doi.org/10.21203/rs.3.rs-718272/v1
https://doi.org/10.21203/rs.3.rs-718272/v1
Publikováno v:
Journal of Drug Delivery Science and Technology. 51:297-309
Alzheimer's disease (AD) is a neurodegenerative disorder affecting the central nervous system (CNS) characterized by the overproduction of amyloid beta proteins and its inability to clear from the brain resulting in its self-aggregation to form toxic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00a30e20a3ee3f8d0fb9e6e15698b872
https://doi.org/10.1016/j.jddst.2019.03.022
https://doi.org/10.1016/j.jddst.2019.03.022