Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Krishnakumar Balasubramanian"'
Autor:
Sun-Jin Kim, Jang-Seong Kim, Eun Sung Park, Ju-Seog Lee, Qingtang Lin, Robert R. Langley, Marva Maya, Junqin He, Seung-Wook Kim, Zhang Weihua, Krishnakumar Balasubramanian, Dominic Fan, Gordon B. Mills, Mien-Chie Hung, Isaiah J. Fidler
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 13, Iss 3, Pp 286-298 (2011)
In the United States, more than 40% of cancer patients develop brain metastasis. The median survival for untreated patients is 1 to 2 months, which may be extended to 6 months with conventional radiotherapy and chemotherapy. The growth and survival o
Externí odkaz:
https://doaj.org/article/298f851c3462484aa6d1fece1afde524
Autor:
Qingtang Lin, Krishnakumar Balasubramanian, Dominic Fan, Sun-Jin Kim, Lixia Guo, Hua Wang, Menashe Bar-Eli, Kenneth D. Aldape, Isaiah J. Fidler
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 12, Iss 9, Pp 748-754 (2010)
Brain metastases are highly resistant to chemotherapy. Metastatic tumor cells are known to exploit the host microenvironment for their growth and survival. We report here that melanoma brain metastases are surrounded and infiltrated by activated astr
Externí odkaz:
https://doaj.org/article/3983dfad37874a64b14cde2803962811
Publikováno v:
SIAM Journal on Optimization. 32:519-544
Publikováno v:
Foundations of Computational Mathematics. 22:35-76
In this paper, we propose and analyze zeroth-order stochastic approximation algorithms for nonconvex and convex optimization, with a focus on addressing constrained optimization, high-dimensional setting, and saddle point avoiding. To handle constrai
Publikováno v:
Journal of Global Optimization.
Publikováno v:
arXiv:2008.03038v2 [stat.ML] for this version, https://doi.org/10.48550/arXiv.2008.03038
37th International Conference on Machine Learning, ICML 2020
37th International Conference on Machine Learning, ICML 2020
We propose a novel stochastic network model, called Fractal Gaussian Network (FGN), that embodies well-defined and analytically tractable fractal structures. Such fractal structures have been empirically observed in diverse applications. FGNs interpo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d7b9ec6015420fb64c4f55a03bc0042
https://bura.brunel.ac.uk/handle/2438/24515
https://bura.brunel.ac.uk/handle/2438/24515
Functionally constrained stochastic optimization problems, where neither the objective function nor the constraint functions are analytically available, arise frequently in machine learning applications. In this work, assuming we only have access to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7314655b586c956790bed8f2170e1c37
We consider stochastic zeroth-order optimization over Riemannian submanifolds embedded in Euclidean space, where the task is to solve Riemannian optimization problem with only noisy objective function evaluations. Towards this, our main contribution
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58d5f391dec09e119032e130f78db0ca
Autor:
Bengt Fadeel, Valerian E. Kagan, John J. Maguire, Krishnakumar Balasubramanian, Sergey Bolevich, Yulia Y. Tyurina, Hülya Bayır
Publikováno v:
Biochemical and Biophysical Research Communications. 482:482-490
High fidelity of biological systems is frequently achieved by duplication of the essential intracellular machineries or, removal of the entire cell, which becomes unnecessary or even harmful in altered physiological environments. Carefully controlled
Autor:
Alexander Star, Alexandr A. Kapralov, Kang Kim, Simon C. Watkins, Claudette M. St. Croix, Valerian E. Kagan, Krishnakumar Balasubramanian, Rama K. Mallampalli, Gregg P. Kotchey, Jaesok Yu, Anna A. Shvedova, Wanji Seo, Elena R. Kisin, Irina I. Vlasova
Publikováno v:
ACS Nano
In contrast to short-lived neutrophils, macrophages display persistent presence in the lung of animals after pulmonary exposure to carbon nanotubes. While effective in the clearance of bacterial pathogens and injured host cells, the ability of macrop