Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Krishnakanth Kondabolu"'
Autor:
Sanaya N. Shroff, Eric Lowet, Sudiksha Sridhar, Howard J. Gritton, Mohammed Abumuaileq, Hua-An Tseng, Cyrus Cheung, Samuel L. Zhou, Krishnakanth Kondabolu, Xue Han
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Rhythmic neural network activity has been broadly linked to behavior. However, it is unclear how membrane potentials of individual neurons track behavioral rhythms, even though many neurons exhibit pace-making properties in isolated brain ci
Externí odkaz:
https://doaj.org/article/ccfc97b3d7934471b978e4eb372e7ff0
Autor:
Eric Lowet, Daniel J. Sheehan, Ulises Chialva, Rodrigo De Oliveira Pena, Rebecca A. Mount, Sheng Xiao, Samuel L. Zhou, Hua-an Tseng, Howard Gritton, Sanaya Shroff, Krishnakanth Kondabolu, Cyrus Cheung, Yangyang Wang, Kiryl D. Piatkevich, Edward S. Boyden, Jerome Mertz, Michael E. Hasselmo, Horacio G. Rotstein, Xue Han
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112906- (2023)
Summary: Hippocampal CA1 neurons generate single spikes and stereotyped bursts of spikes. However, it is unclear how individual neurons dynamically switch between these output modes and whether these two spiking outputs relay distinct information. We
Externí odkaz:
https://doaj.org/article/b5652001c01443b4ab56188e0408577e
Autor:
Eric Lowet, Krishnakanth Kondabolu, Samuel Zhou, Rebecca A. Mount, Yangyang Wang, Cara R. Ravasio, Xue Han
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
The neurophysiological mechanisms of deep brain stimulation remain poorly understood. Through fluorescence voltage imaging of individual hippocampal neurons in awake mice, the authors show that deep brain stimulation causes membrane depolarization th
Externí odkaz:
https://doaj.org/article/67ed8e80dd574b169643646150610599
Publikováno v:
Brain Stimulation, Vol 16, Iss 1, Pp 242- (2023)
Externí odkaz:
https://doaj.org/article/d1df144a64d34c69a86d7932f8fd2a73
Autor:
Daniel Dautan, Icnelia Huerta-Ocampo, Nadine K. Gut, Miguel Valencia, Krishnakanth Kondabolu, Yuwoong Kim, Todor V. Gerdjikov, Juan Mena-Segovia
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-19 (2020)
Acetylcholine (ACh) in the striatum is involved in mediating action flexibility. Here the authors show that midbrain cholinergic nuclei provide a new source of Ach in the striatum, form excitatory synapses with striatal cholinergic interneurons (CIN)
Externí odkaz:
https://doaj.org/article/d9ef9606aeda407eb4073590fbf4e724
Autor:
Koós T, Peter J. Magill, Daniela Calvigioni, Natalie M. Doig, Konstantinos Meletis, Krishnakanth Kondabolu, Ayeko O, Torres A, Bakhtawer Khan
The striatum and subthalamic nucleus (STN) are considered to be the primary input nuclei of the basal ganglia. Projection neurons of both striatum and STN can extensively interact with other basal ganglia nuclei, and there is growing anatomical evide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45061522a5848162a9522c317fc8f8e4
https://ora.ox.ac.uk/objects/uuid:44bf4707-cabc-465b-89ae-561289ef8b25
https://ora.ox.ac.uk/objects/uuid:44bf4707-cabc-465b-89ae-561289ef8b25
Autor:
Hussain Y. Khdour, Krishnakanth Kondabolu, Alina Khadka, Maxime Assous, James M. Tepper, Tracy S. Tran, Pierre-Olivier Polack
Publikováno v:
J Neurosci
The functions of cortical networks are progressively established during development by series of events shaping the neuronal connectivity. Synaptic elimination, which consists of removing the supernumerary connections generated during the earlier sta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dfe28a5d339929bcca70a43aae6e178
https://europepmc.org/articles/PMC9188426/
https://europepmc.org/articles/PMC9188426/
Autor:
Eric Lowet, Daniel J. Sheehan, Rebecca A. Mount, Sheng Xiao, Samuel L. Zhou, Hua-an Tseng, Howard Gritton, Sanaya Shroff, Krishnakanth Kondabolu, Cyrus Cheung, Jerome Mertz, Michael E. Hasselmo, Xue Han
Hippocampal neurons generate either single spikes or stereotyped bursts of spikes known as complex spikes. Although single and complex spikes co-occur in the same neuron, their contribution to information processing remains unclear. We analyzed hippo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::688fbbc4286f2e48e12b8cd54d3365d9
https://doi.org/10.1101/2022.04.06.487256
https://doi.org/10.1101/2022.04.06.487256
Deep brain stimulation (DBS) is a promising neuromodulation therapy that alters neural activity via intracranial electrical stimulation. However, the neurophysiological mechanisms of DBS remain largely unknown, because of the difficulty of obtaining
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::117b8b20cc8a26193885f4081ae96570
https://doi.org/10.1101/2022.03.26.485926
https://doi.org/10.1101/2022.03.26.485926
Dopamine enables purposive behavior and adjusts vigor as a function of the relative value of actions. In Parkinson’s disease, dopamine neurons die and give rise to a series of motor and cognitive changes that interfere with the expression of voliti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::148841e4f7561f00c7bf4d45758a4bab
https://doi.org/10.1101/2022.01.18.476772
https://doi.org/10.1101/2022.01.18.476772