Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Krishna Vukoti"'
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46290 (2012)
Elucidation of the molecular mechanisms of activation of G protein-coupled receptors (GPCRs) is among the most challenging tasks for modern membrane biology. For studies by high resolution analytical methods, these integral membrane receptors have to
Externí odkaz:
https://doaj.org/article/20c95ed5830543f8868b2772645ff37e
Publikováno v:
Journal of Integrated OMICS. 8
Dauer larva is an alternative developmental stage of Caenorhabditis elegans ( C. elegans ) that occurs when the environmental condition is unfavorable for growth. Little is known regarding how the proteome of dauer larvae respond to poor environmenta
Autor:
Sudipto Saha, Xiaokun Yu, Masaru Miyagi, Krishna Vukoti, Zhaoyang Feng, Ao Lin Hsu, Quanhu Sheng
Publikováno v:
Journal of Proteome Research. 14:1483-1494
Little is known regarding how the synthesis and degradation of individual proteins change during the life of an organism. Such knowledge is vital to understanding the aging process. To fill this knowledge gap, we monitored newly synthesized proteins
Autor:
Alexei Yeliseev, Klaus Gawrisch, Patricia H. Reggio, Diane L. Lynch, Alan Grossfield, Michael C. Pitman, Tomohiro Kimura, Dow P. Hurst, Krishna Vukoti
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 82:452-465
Autor:
Kenner C. Rice, Alexei Yeliseev, Tomohiro Kimura, Klaus Gawrisch, Kejun Cheng, Steven D. Rhodes, Krishna Vukoti
Publikováno v:
Journal of Biological Chemistry. 287:4076-4087
Human cannabinoid type 2 (CB(2)) receptor expressed in Escherichia coli was purified and successfully reconstituted in the functional form into lipid bilayers composed of POPC, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 1-palmitoyl-2-oleoyl-sn
Autor:
Krishna Vukoti, Alexei Yeliseev
Publikováno v:
Production of Membrane Proteins: Strategies for Expression and Isolation
Publikováno v:
Acta crystallographica. Section D, Biological crystallography. 70(Pt 3)
With more than 500 crystal structures determined, serine proteases make up greater than one-third of all proteases structurally examined to date, making them among the best biochemically and structurally characterized enzymes. Despite the numerous cr
Autor:
Tomohiro, Kimura, Krishna, Vukoti, Diane L, Lynch, Dow P, Hurst, Alan, Grossfield, Michael C, Pitman, Patricia H, Reggio, Alexei A, Yeliseev, Klaus, Gawrisch
Publikováno v:
Proteins. 82(3)
The global fold of human cannabinoid type 2 (CB2 ) receptor in the agonist-bound active state in lipid bilayers was investigated by solid-state (13)C- and (15)N magic-angle spinning (MAS) NMR, in combination with chemical-shift prediction from a stru
Streptomyces erythraeus trypsin (SET) is a serine protease that is secreted extracellularly by S. erythraeus. We investigated the inhibitory effect of α1-antitrypsin on the catalytic activity of SET. Intriguingly, we found that SET is not inhibited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f546b2e3f059101d587aace84f0c79b
https://europepmc.org/articles/PMC3236438/
https://europepmc.org/articles/PMC3236438/
Publikováno v:
Biophysical Journal. 98(3)
The human peripheral cannabinoid receptor CB2 is abundant in tissues of immune and hematopoietic systems. CB2 belongs to the class of heptahelical G-protein coupled receptors and regulates a wide range of physiological functions through binding of en