Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Krishna Vaddi"'
How do you keep track of basic information on the proteins you work with? Where do you find details of their physicochemical properties, amino acid sequences, gene organization? Are you tired of scanning review articles, primary papers and databases
Publikováno v:
The Indian Journal of Pediatrics. 85:836-840
To investigate the knowledge, attitude, and practice of Infantile Spasms among pediatricians. A survey was carried out among pediatricians serving in Punjab, Haryana, Chandigarh, Himachal Pradesh and Delhi. The survey was done by Survey Monkey Softwa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41e4150b3b78ca0711a4deb7b6cca130
https://doi.org/10.1007/s12098-018-2630-3
https://doi.org/10.1007/s12098-018-2630-3
Publikováno v:
Fair Disclosure Wire (Quarterly Earnings Reports). 09/14/2022.
Publikováno v:
Clinical Drug Investigation. 38:563-564
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd7b01eff9da5f3cecaeb05feed09380
https://doi.org/10.1007/s40261-018-0640-6
https://doi.org/10.1007/s40261-018-0640-6
Publikováno v:
Fair Disclosure Wire (Quarterly Earnings Reports). 09/12/2023.
Autor:
Gregory R. Ott, Krishna Vaddi, Rui-Qin Liu, Rajan Anand, Jingwu Duan, James M. Trzaskos, Maryanne B. Covington, David D. Christ, Zhonghui Lu, Mingxin Qian, Robert C. Newton
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:1958-1962
Potent and selective inhibitors of tumor necrosis factor-alpha converting enzyme (TACE) were discovered with several new heterocyclic P1' groups in conjunction with cyclic beta-amino hydroxamic acid scaffolds. Among them, the pyrazolopyridine provide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f246d04dc5f8f53a5a66321c035d9eea
https://doi.org/10.1016/j.bmcl.2008.01.120
https://doi.org/10.1016/j.bmcl.2008.01.120
Autor:
Maryanne B. Covington, Zhonghui Lu, Rui-Qin Liu, James M. Trzaskos, Rajan Anand, Gregory R. Ott, Jingwu Duan, Robert C. Newton, Krishna Vaddi, Mingxin Qian, Naoyuki Asakawa, David D. Christ
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:1577-1582
Novel ((2-substituted-1H-benzo[d]imidazol-1-yl)methyl)benzamides were found to be excellent P1' substituents in conjunction with unique constrained beta-amino hydroxamic acid scaffolds for the discovery of potent selective inhibitors of TNF-alpha Con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2b6f2a36e543037e9fb95cda7154bf4
https://doi.org/10.1016/j.bmcl.2008.01.075
https://doi.org/10.1016/j.bmcl.2008.01.075
Autor:
Yevgeniya I. Orlovsky, Nicole Stowell, Anuk M. Das, David D. Christ, Kimberly A. Solomon, Dean A. Wacker, Douglas G. Batt, Lori L. Bostrom, Danielle M. Graden, Soo S. Ko, Erin McLaughlin, Carl P. Decicco, Gregory C. Houghton, Eric A. Wadman, Swamy Yeleswaram, Ilona Kariv, Percy H. Carter, Patricia K. Welch, Jeffrey G. Varnes, Robert C. Newton, Maryanne B. Covington, Paul Davies, James R. Pruitt, Shon K. Booker, Krishna Vaddi
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:2992-2997
DPC168, a benzylpiperidine-substituted aryl urea CCR3 antagonist evaluated in clinical trials, was a relatively potent inhibitor of the 2D6 isoform of cytochrome P-450 (CYP2D6). Replacement of the cyclohexyl central ring with saturated heterocycles p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a1dd9c1a66cffc3a8a13b4d5ed114b4
https://doi.org/10.1016/j.bmcl.2007.03.065
https://doi.org/10.1016/j.bmcl.2007.03.065
Autor:
Krishna Vaddi, Carrie Brodmerkel
Publikováno v:
Current Opinion in Biotechnology. 14:652-658
Inflammatory diseases affect a significant portion of the population worldwide and have been intensely studied for several decades. The advent of transgenic technology has allowed researchers to study individual gene contributions to the pathogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ad365eddbcea734f12a2cac77f279d6
https://doi.org/10.1016/j.copbio.2003.10.001
https://doi.org/10.1016/j.copbio.2003.10.001
Autor:
Chu-Biao Xue, Xiaohua He, John Roderick, Ronald L Corbett, James J.-W Duan, Rui-Qin Liu, Maryanne B Covington, Mingxin Qian, Maria D Ribadeneira, Krishna Vaddi, David D Christ, Robert C Newton, James M Trzaskos, Ronald L Magolda, Ruth R Wexler, Carl P Decicco
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 13:4299-4304
Modifications of the lead TACE inhibitor 1 (N-hydroxy-trans-2-{[4-(4-quinolinyloxymethyl)anilinyl]carbonyl}-1-cyclohexanecarboxamide) at the cyclohexyl ring and the quinoline moiety led to the identification of a series of piperidine containing TACE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e77c3dec33f6160bdbe29873bacd31d0
https://doi.org/10.1016/j.bmcl.2003.09.057
https://doi.org/10.1016/j.bmcl.2003.09.057