Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Krishna Seshu Tummala"'
Autor:
Nabeel Bardeesy, Robert T. Manguso, Hongwu Zheng, Rahul M. Kohli, Vikram Deshpande, Brandon Nicolay, Lipika Goyal, Cristina R. Ferrone, Mathias Heikenwälder, Tong Wang, Russell W. Jenkins, Rodrigo Saad-Berreta, Yi Sun, Sebastien Ronseaux, Christine Hudson, Mirian Fernández-Vaquero, María García-Beccaria, William Shen, Meiqi Luo, Qibiao Wu, Yuanli Zhen, Vajira Weeresekara, Krishna Seshu Tummala, Amaya Pankaj, Ramzi Adil, Kira E. Olander, Emily Kessler, Ting-Yu Wei, Vindhya Vijay, Joshua Merritt, Juan Dubrot, Lei Shi, Meng-Ju Wu
Supplementary table from Mutant IDH Inhibits IFNγ–TET2 Signaling to Promote Immunoevasion and Tumor Maintenance in Cholangiocarcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4591e78e7671b476dda13e33c1b01770
https://doi.org/10.1158/2159-8290.22541389
https://doi.org/10.1158/2159-8290.22541389
Autor:
Nabeel Bardeesy, Robert T. Manguso, Hongwu Zheng, Rahul M. Kohli, Vikram Deshpande, Brandon Nicolay, Lipika Goyal, Cristina R. Ferrone, Mathias Heikenwälder, Tong Wang, Russell W. Jenkins, Rodrigo Saad-Berreta, Yi Sun, Sebastien Ronseaux, Christine Hudson, Mirian Fernández-Vaquero, María García-Beccaria, William Shen, Meiqi Luo, Qibiao Wu, Yuanli Zhen, Vajira Weeresekara, Krishna Seshu Tummala, Amaya Pankaj, Ramzi Adil, Kira E. Olander, Emily Kessler, Ting-Yu Wei, Vindhya Vijay, Joshua Merritt, Juan Dubrot, Lei Shi, Meng-Ju Wu
Supplementary Figure from Mutant IDH Inhibits IFNγ–TET2 Signaling to Promote Immunoevasion and Tumor Maintenance in Cholangiocarcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1f285ec531b322829e126b3586d7fc7
https://doi.org/10.1158/2159-8290.22541395.v1
https://doi.org/10.1158/2159-8290.22541395.v1
Autor:
Nabeel Bardeesy, Robert T. Manguso, Hongwu Zheng, Rahul M. Kohli, Vikram Deshpande, Brandon Nicolay, Lipika Goyal, Cristina R. Ferrone, Mathias Heikenwälder, Tong Wang, Russell W. Jenkins, Rodrigo Saad-Berreta, Yi Sun, Sebastien Ronseaux, Christine Hudson, Mirian Fernández-Vaquero, María García-Beccaria, William Shen, Meiqi Luo, Qibiao Wu, Yuanli Zhen, Vajira Weeresekara, Krishna Seshu Tummala, Amaya Pankaj, Ramzi Adil, Kira E. Olander, Emily Kessler, Ting-Yu Wei, Vindhya Vijay, Joshua Merritt, Juan Dubrot, Lei Shi, Meng-Ju Wu
Isocitrate dehydrogenase 1 mutations (mIDH1) are common in cholangiocarcinoma. (R)-2-hydroxyglutarate generated by the mIDH1 enzyme inhibits multiple α-ketoglutarate–dependent enzymes, altering epigenetics and metabolism. Here, by developing mIDH1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28dbb03d0373c9d903a08ccbd12df350
https://doi.org/10.1158/2159-8290.c.6549628.v1
https://doi.org/10.1158/2159-8290.c.6549628.v1
Autor:
Harun Ozturk, Harun Cingoz, Turan Tufan, Jiekun Yang, Sara J. Adair, Krishna Seshu Tummala, Cem Kuscu, Meric Kinali, Gamze Comertpay, Sarbajeet Nagdas, Bernadette J. Goudreau, Husnu Umit Luleyap, Yagmur Bingul, Timothy B. Ware, William L. Hwang, Ku-lung Hsu, David F. Kashatus, David T. Ting, Navdeep S. Chandel, Nabeel Bardeesy, Todd W. Bauer, Mazhar Adli
Publikováno v:
Developmental cell. 57(11)
Pancreatic ductal adenocarcinoma (PDA) cells reprogram their transcriptional and metabolic programs to survive the nutrient-poor tumor microenvironment. Through in vivo CRISPR screening, we discovered islet-2 (ISL2) as a candidate tumor suppressor th