Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Krishna P. Sigdel"'
Publikováno v:
Membranes, Vol 13, Iss 11, p 864 (2023)
Antimicrobial peptides are key components of the immune system. These peptides affect the membrane in various ways; some form nano-sized pores, while others only produce minor defects. Since these peptides are increasingly important in developing ant
Externí odkaz:
https://doaj.org/article/d2555c2947744cf1be34fd20db61d42f
Autor:
Ioan Kosztin, Milica Utjesanovic, Krishna P. Sigdel, Tina R. Matin, Virginia F. Smith, Gavin M. King
Publikováno v:
Langmuir : the ACS journal of surfaces and colloids. 36(8)
Quantitative characterization of the strength of peripheral membrane protein-lipid bilayer interactions is fundamental in the understanding of many protein targeting pathways. SecA is a peripheral membrane protein that plays a central role in translo
Autor:
Krishna P. Sigdel, Katherine G. Schaefer, P.H. Nguyen, Arthur G. Roberts, Gavin M. King, Gershon A. K. Mensah
Publikováno v:
Biochem Pharmacol
P-glycoprotein (Pgp) is an ATP-dependent efflux transporter and plays a major role in anti-cancer drug resistance by pumping a chemically diverse range of cytotoxic drugs from cancerous tumors. Despite numerous studies with the transporter, the molec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67641529d23abf049392a347b40d428c
https://europepmc.org/articles/PMC8262137/
https://europepmc.org/articles/PMC8262137/
Publikováno v:
Biochemical Pharmacology. 156:302-311
The membrane-bound P-glycoprotein (Pgp) transporter plays a major role in human disease and drug disposition because of its ability to efflux a chemically diverse range of drugs through ATP hydrolysis and ligand-induced conformational changes. Deciph
Autor:
Raghavendar Reddy Sanganna Gari, Gavin M. King, Nagaraju Chada, Krishna P. Sigdel, Brendan P. Marsh
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports
Scientific Reports
Imaging by atomic force microscopy (AFM) offers high-resolution descriptions of many biological systems; however, regardless of resolution, conclusions drawn from AFM images are only as robust as the analysis leading to those conclusions. Vital to th
Publikováno v:
The FASEB Journal. 33
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1814
Atomic force microscopy (AFM)-based force spectroscopy is a powerful technique which has seen significant enhancements in both force and time resolution in recent years. This chapter details two AFM cantilever modification procedures that yield high
Publikováno v:
Methods in Molecular Biology ISBN: 9781493985906
Atomic force microscopy (AFM)-based force spectroscopy is a powerful technique which has seen significant enhancements in both force and time resolution in recent years. This chapter details two AFM cantilever modification procedures that yield high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57948d7a06fa1aa9fd1f0714e1cdde9e
https://doi.org/10.1007/978-1-4939-8591-3_4
https://doi.org/10.1007/978-1-4939-8591-3_4
Autor:
Brendan P. Marsh, Krishna P. Sigdel, Milica Utjesanovic, Tina R. Matin, Ioan Kosztin, Virginia F. Smith, Fabio Gallazzi, Gavin M. King
Publikováno v:
Langmuir : the ACS journal of surfaces and colloids. 33(16)
Interactions between short protein segments and phospholipid bilayers dictate fundamental aspects of cellular activity and have important applications in biotechnology. Yet, the lack of a suitable methodology for directly probing these interactions h
Publikováno v:
Biophysical Journal. 114:273a-274a