Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Krishna P Subedi"'
Autor:
Amit Sharma Bhattarai, Bidur Adhikari, Deepak Raj Joshi, Alisha Yadav, Pankaj Joshi, Bashu Dev Parajuli, Megha Koirala, Kushal Jung Karki, Krishna Prasad Subedi, Gentle Sunder Shrestha, Anil Shrestha, Shreejana Singh
Publikováno v:
Journal of Nepal Health Research Council, Vol 22, Iss 01 (2024)
Background: Organ transplant is the procedure of replacing a failing or damaged organ with a functioning one. Positive attitude and awareness about donation are a must for donor organs to be available. This study explored the level of knowledge, perc
Externí odkaz:
https://doaj.org/article/3fe06e464f944cc8a6d1ecd583ab3b4f
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract A severe consequence of radiation therapy in patients with head and neck cancer is persistent salivary gland hypofunction which causes xerostomia and oral infections. We previously showed that irradiation (IR) of salivary glands in mice trig
Externí odkaz:
https://doaj.org/article/db207e2ba12f48e08b162307148ad41f
Autor:
Gambhir Shrestha, Prakash Neupane, Nirmal Lamichhane, Bijaya Chandra Acharya, Bhola Siwakoti, Krishna Prasad Subedi, Kishore Kumar Pradhananga, Rashmi Mulmi
Publikováno v:
Asian Pacific Journal of Cancer Care, Vol 5, Iss 3, Pp 145-150 (2020)
Background: Cancer is an major public health problem in the world. This study aims to present a three-year trend of cancer incidence in Nepal. Methods: This study used the three-year data of National Cancer Registry Program (NCRP) from January 2013 t
Externí odkaz:
https://doaj.org/article/150bd8e4226b4650ae95db0672801779
Publikováno v:
Cell Reports, Vol 23, Iss 2, Pp 522-534 (2018)
Summary: Ca2+ entry mediated by the calcium channel, Orai1, provides critical Ca2+ signals that regulate cell function. The ER-Ca2+ sensor protein, STIM1, recruits and strongly activates Orai1 within ER-PM junctions. STIM2 is a poor activator of Orai
Externí odkaz:
https://doaj.org/article/bb7c0df20fac4dfda89aa2cb0a6c27b2
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/ad89e49480ed43249ad651114af68e81
Autor:
Krishna P. Subedi, Min-Jeong Son, Bojjibabu Chidipi, Seong-Woo Kim, Jun Wang, Kyeong-Hee Kim, Sun-Hee Woo, Joon-Chul Kim
Publikováno v:
Cellular Physiology and Biochemistry, Vol 41, Iss 1, Pp 399-412 (2017)
Background/Aims: Endothelin-1 (ET-1) and the α1-adrenoceptor agonist phenylephrine (PE) activate cAMP response element binding protein (CREB), a transcription factor implicated in cardiac hypertrophy. The signaling pathway involved in CREB activatio
Externí odkaz:
https://doaj.org/article/8efb949f655449b5a13e7f4c0eaaea92
Autor:
Gambhir Shrestha, Kishore Kumar Pradhananga, Rashmi Mulmi, Krishna Prasad Subedi, Bhola Siwakoti
Publikováno v:
Journal of Nepal Medical Association, Vol 57, Iss 216 (2019)
Cancer registration is an organization for the systematic collection, storage, analysis, interpretation and reporting of data on subjects with cancer. Cancer Registry was initiated in 1995 and expanded as National Cancer Registry Program since 2003 b
Externí odkaz:
https://doaj.org/article/26380f348a084a65a91a9344676933aa
Autor:
Chun Huang, Jinxing Hu, Krishna P. Subedi, Amanda H.Y. Lin, Omkar Paudel, Pixin Ran, James S.K. Sham
Publikováno v:
Cellular Physiology and Biochemistry, Vol 37, Iss 5, Pp 2043-2059 (2015)
Background/Aims: Adenosine diphosphate ribose (ADPR), a product of β-NAD+ metabolism generated by the multifunctional enzyme CD38, is recognized as a novel signaling molecule. The catalytic site of CD38 orients extracellularly or intracellularly, ca
Externí odkaz:
https://doaj.org/article/194cdc97e03d4dae8b8a5143b4ac8d8e
Autor:
Krishna P Subedi, Shashank Timilsina, Krishna Kumar Yadav, Suraj Shrestha, Prasan B S Kansakar
Publikováno v:
Journal of Surgical Case Reports. 2022
Intussusception is a rare condition in adults and presents a diagnostic challenge. Clinical presentation tends to be chronic and non-specific. Unlike the pediatric population, most adult intussusceptions have structural lesions as lead points. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea96f5bca30abab89e3b87eb42fef808
https://doi.org/10.1093/jscr/rjac343
https://doi.org/10.1093/jscr/rjac343
Autor:
Krishna P. Subedi, Rajesh Bhardwaj, Indu S. Ambudkar, Hassan Saadi, Hwei Ling Ong, Changyu Zheng, Stefan Feske, Ga-Yeon Son, Lucile Noyer
Publikováno v:
Proceedings of the National Academy of Sciences. 117:16638-16648
The Orai1 channel is regulated by stromal interaction molecules STIM1 and STIM2 within endoplasmic reticulum (ER)-plasma membrane (PM) contact sites. Ca2+ signals generated by Orai1 activate Ca2+-dependent gene expression. When compared with STIM1, S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe97cf819c3acf3329c989aa1037a1e7
https://doi.org/10.1073/pnas.1915386117
https://doi.org/10.1073/pnas.1915386117