Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Krishna P Kota"'
Autor:
Rajini Mudhasani, Julie P Tran, Cary Retterer, Krishna P Kota, Chris A Whitehouse, Sina Bavari
Publikováno v:
PLoS Pathogens, Vol 12, Iss 2, p e1005437 (2016)
Activated protein kinase R (PKR) plays a vital role in antiviral defense primarily by inhibiting protein synthesis and augmenting interferon responses. Many viral proteins have adopted unique strategies to counteract the deleterious effects of PKR. T
Externí odkaz:
https://doaj.org/article/e3459fd33816492ab29a9a822f32e355
Autor:
Chih-Yuan eChiang, Ijeoma eUzoma, Douglas eLane, Vesna eMemišević, Farhang eAlem, Kuan eYao, Krishna P Kota, Sina eBavari, Anders eWallqvist, Ramin eHakami, Rekha ePanchal
Publikováno v:
Frontiers in Microbiology, Vol 6 (2015)
Burkholderia is a diverse genus of Gram-negative bacteria that cause high mortality rate in humans and cattle. The lack of effective therapeutic treatments poses serious public health threats. Insights toward host-Burkholderia spp. interaction are cr
Externí odkaz:
https://doaj.org/article/e4df7e0d7568479dba85540ace8945d4
Autor:
Rajini Mudhasani, Krishna P Kota, Cary Retterer, Julie P Tran, Chris A Whitehouse, Sina Bavari
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 8, p e3095 (2014)
High content image-based screening was developed as an approach to test a protease inhibitor small molecule library for antiviral activity against Rift Valley fever virus (RVFV) and to determine their mechanism of action. RVFV is the causative agent
Externí odkaz:
https://doaj.org/article/f343e9cdd9a846528fae76d2b93b34c1
Autor:
Felicia D Langel, Chih-Yuan Chiang, Douglas Lane, Tara Kenny, Jenifer F Ojeda, Yang Zhong, Jianwei Che, Yingyao Zhou, Wilson Ribot, Krishna P Kota, Sina Bavari, Rekha G Panchal
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e87201 (2014)
Alveolar macrophages (AMs) phagocytose Bacillus anthracis following inhalation and induce the production of pro-inflammatory cytokines and chemokines to mediate the activation of innate immunity. Ames, the virulent strain of B. anthracis, contains tw
Externí odkaz:
https://doaj.org/article/41579968887f4aceb1ffbdfacac54d16
Autor:
Jonathan E Nuss, Kylene Kehn-Hall, Ashwini Benedict, Julie Costantino, Michael Ward, Brian D Peyser, Cary J Retterer, Lyal E Tressler, Laura M Wanner, Hugh F McGovern, Anum Zaidi, Scott M Anthony, Krishna P Kota, Sina Bavari, Ramin M Hakami
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e93483 (2014)
Rift Valley fever is a potentially fatal disease of humans and domestic animals caused by Rift Valley fever virus (RVFV). Infection with RVFV in ruminants can cause near 100% abortion rates and recent outbreaks in naïve human populations have sugges
Externí odkaz:
https://doaj.org/article/c96143c0a8d945fcb90fafb7f6419a2f
Autor:
Krishna P Kota, Brett Eaton, Douglas Lane, Melanie Ulrich, Ricky Ulrich, Brian D Peyser, Camenzind G Robinson, James G Jaissle, Gianluca Pegoraro, Sina Bavari, Rekha G Panchal
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e55167 (2013)
The molecular machinery that regulates the entry and survival of Yersinia pestis in host macrophages is poorly understood. Here, we report the development of automated high-content imaging assays to quantitate the internalization of virulent Y. pesti
Externí odkaz:
https://doaj.org/article/15728c4af58a4e93b1a9471e1e51631f
Orally available nucleoside analog UMM-766 provides protection in a murine model of orthopox disease
Autor:
Rajini R. Mudhasani, Joseph W. Golden, Gregory C. Adam, Timothy J. Hartingh, Krishna P. Kota, David Ordonez, Corey R. Quackenbush, Julie P. Tran, Curtis Cline, Janice A. Williams, Xiankun Zeng, David B. Olsen, Linda A. Lieberman, Christopher Boyce, Anthony Ginnetti, J. Matthew Meinig, Rekha G. Panchal, Eric M. Mucker
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 4 (2024)
ABSTRACTAlthough smallpox has been eradicated, other orthopoxviruses continue to be a public health concern as exemplified by the ongoing Mpox (formerly monkeypox) global outbreak. While medical countermeasures (MCMs) previously approved by the Food
Externí odkaz:
https://doaj.org/article/53df8f67d29d4344baea9e9e6311d3a1
Autor:
Krishna P. Kota, Ilya Trakht, Gavreel Kalantarov, David Ordonez, Jiayi Wei, Stephanie Trefry, Evia Bavari, Jenny Richardson, Rouzbeh Zamani, Christy Raney, Farooq Nasar, Bruce Daugherty, Seth Lederman, Sina Bavari
Publikováno v:
Microorganisms, Vol 12, Iss 8, p 1503 (2024)
Convalescent sera, rich in pathogen-specific antibodies, offers passive immunity to patients with infectious diseases. Screening assays using convalescent sera are crucial for evaluating therapeutic efficacy, selecting suitable serum donors, and stan
Externí odkaz:
https://doaj.org/article/c27fc2fd71dc4f7a9ac91a089199d803
Autor:
Archana Verma, Krishna Kiran Kota, Sampada Bangar, Girish Rahane, Nayana Yenbhar, Seema Sahay
Publikováno v:
Child and Adolescent Psychiatry and Mental Health, Vol 17, Iss 1, Pp 1-16 (2023)
Abstract Background Development of emotional distress (ED) among adolescents living with perinatally acquired HIV (ALPHIV) affects their adherence behaviour and social and psychological functioning. Data on stressors among ALPHIV demonstrates the gap
Externí odkaz:
https://doaj.org/article/0c3b25b4a92c4d1cad69a8942bc2d4de
Publikováno v:
Textile & Leather Review, Vol 5, Pp 296-326 (2022)
The Textile Industry is one of the largest industrial sectors and the fifth largest exporter of the textiles employing 45 million workers in India. The Indian textile industry has changed its ways in the production of finished textiles, Energy is inv
Externí odkaz:
https://doaj.org/article/67719f05444c40d1b224c1b5ecadd46b