Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Krishna M Talasila"'
Autor:
Krishna M Talasila, Narve Brekka, Kjersti Mangseth, Daniel Stieber, Lasse Evensen, Gro V Rosland, Anja Torsvik, Marek Wagner, Simone P Niclou, Rupavathana Mahesparan, Olav K Vintermyr, Rolf Bjerkvig, Janice M Nigro, Hrvoje Miletic
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e81183 (2013)
Two of the signature genetic events that occur in human gliomas, EGFR amplification and IDH mutation, are poorly represented in experimental models in vitro. EGFR amplification, for example, occurs in 40 to 50% of GBM, and yet, EGFR amplification is
Externí odkaz:
https://doaj.org/article/e11b2a7f9c3149ffb7dc882e61c265ab
Autor:
Kristoffer Riecken, Sandra Ninzima, Abdul Latif, Jiwan Ghimire, Francisco Azuaje, Krishna M. Talasila, Lars A. Rømo Ystaas, Jubayer A Hossain, Rolf Bjerkvig, Arnaud Muller, Justin V. Joseph, Boris Fehse, Hrvoje Miletic
Publikováno v:
Neuro-Oncology
Neuro Oncol
Neuro Oncol
Background Suicide gene therapy for malignant gliomas has shown encouraging results in the latest clinical trials. However, prodrug application was most often restricted to short-term treatment (14 days), especially when replication-defective vectors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9e0130031f3ba9ea7099c5e2dacddb4
https://doi.org/10.1093/neuonc/noz060
https://doi.org/10.1093/neuonc/noz060
Autor:
Frits Thorsen, Michael Andersen, Francisco Azuaje, Irene H. Flønes, Simone P. Niclou, Krishna M. Talasila, Laurent Vallar, Karl Johan Tronstad, Eskil Eskilsson, Michel Mittelbronn, Patrick N. Harter, Hanne R. Hagland, Rolf Bjerkvig, Hrvoje Miletic, Sabrina Fritah, Nadia A. Atai, Jubayer A Hossain, Justin V. Joseph, Gro V. Røsland, Cornelis J.F. Van Noorden, Charalampos Tzoulis
Publikováno v:
Neuro-oncology, 19(3), 383-393. Oxford University Press
Background Invasion and angiogenesis are major hallmarks of glioblastoma (GBM) growth. While invasive tumor cells grow adjacent to blood vessels in normal brain tissue, tumor cells within neovascularized regions exhibit hypoxic stress and promote ang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8e946cb3042f9f8f7ab048456e93e5a
https://doi.org/10.1093/neuonc/now175
https://doi.org/10.1093/neuonc/now175
Autor:
Anne Margrete Øyan, Ercan Mutlu, Jian Wang, Oleg Tsinkalovsky, Linda Sleire, Xingang Li, Nicolas H.C. Brons, Tao Yan, Mireille Kayitesi Johannessen, Kjell Petersen, Siddharta S. Mitra, Hege Karine Jacobsen, Krishna M. Talasila, Mohummad Aminur Rahman, Hrvoje Miletic, Lina Leiss, Per Øyvind Enger, Karl-Henning Kalland, Inge Jonassen
Publikováno v:
BMC Cancer
Background Little is known about the role of glial host cells in brain tumours. However, supporting stromal cells have been shown to foster tumour growth in other cancers. Methods We isolated stromal cells from patient-derived glioblastoma (GBM) xeno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13854031e5332508e10433f3ff7ed02f
https://hdl.handle.net/1956/17440
https://hdl.handle.net/1956/17440
Autor:
Helena Motaln, Tamara Lah Turnšek, Monika Primon, Hrvoje Miletic, Peter C. Huszthy, Krishna M. Talasila, Rolf Bjerkvig, Nadia A. Atai
Publikováno v:
Experimental cell research, 356(1), 64-73. Academic Press Inc.
Low-grade, pilocytic astrocytomas are treated by resection, but additional therapy is necessary for those tumors with anaplastic features. Arsenic trioxide (As2O3) is emerging as an effective chemotherapeutic agent for treatment of malignant glioblas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c657b57411e05b0c8e5cc352373a2dfd
https://pure.amc.nl/en/publications/cathepsin-l-silencing-increases-as2o3-toxicity-in-malignantly-transformed-pilocytic-astrocytoma-mpa58-cells-by-activating-caspases-37(462e784c-4b3b-4a4e-a6f6-e66b2486a661).html
https://pure.amc.nl/en/publications/cathepsin-l-silencing-increases-as2o3-toxicity-in-malignantly-transformed-pilocytic-astrocytoma-mpa58-cells-by-activating-caspases-37(462e784c-4b3b-4a4e-a6f6-e66b2486a661).html
Autor:
Bernhard Radlwimmer, Narve Brekka, Rolf Bjerkvig, Hrvoje Miletic, Christel Herold-Mende, Katja Tiemann, Neza Podergajs, Krishna M. Talasila, Tamara T. Lah, Uros Rajcevic
Publikováno v:
Radiology and Oncology
Radiology and oncology (Ljubljana)
Radiology and oncology (Ljubljana)
Background. Patient-derived glioblastoma (GBM) stem-like cells (GSCs) represent a valuable model for basic and therapeutic research. GSCs are usually propagated in serum-free Neural Basal medium supplemented with bFGF and EGF. Yet, the exact influenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc532ee0811f76dad18fefae3cb15252
https://doi.org/10.2478/raon-2013-0063
https://doi.org/10.2478/raon-2013-0063
Autor:
Tamara Lah Turnšek, Rolf Bjerkvig, Peter C. Huszthy, Krishna M. Talasila, Monika Primon, Ana Torkar, Helena Motaln
Publikováno v:
Experimental Cell Research. 319:2637-2648
Despite improved treatment options, glioblastoma multiforme (GBM) remains the most aggressive brain tumour with the shortest post-diagnostic survival. Arsenite (As2O3) is already being used in the treatment of acute promyelocytic leukaemia (APL), yet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9a531ac993c2ca35064861aed65bb75
https://doi.org/10.1016/j.yexcr.2013.08.011
https://doi.org/10.1016/j.yexcr.2013.08.011
Autor:
Narve Brekka, Olav Karsten Vintermyr, Per Øystein Sakariassen, Philipp Euskirchen, Anke Soentgerath, Hrvoje Miletic, Eskil Eskilsson, Simone P. Niclou, Morten Lund-Johansen, Gro V. Røsland, Ingrid Moen, Krishna M. Talasila, Olivier Keunen, Lars Prestegarden, Janice M. Nigro, Rolf Bjerkvig, Per Øyvind Enger, Daniel Stieber, Kai Ove Skaftnesmo, Sverre Mørk, Peter C. Huszthy, Jian Wang
Publikováno v:
Acta Neuropathologica
Angiogenesis is regarded as a hallmark of cancer progression and it has been postulated that solid tumor growth depends on angiogenesis. At present, however, it is clear that tumor cell invasion can occur without angiogenesis, a phenomenon that is pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c93d3be527c9b95da08d794a0246f4b7
http://europepmc.org/articles/PMC3631314
http://europepmc.org/articles/PMC3631314
Autor:
Monika, Primon, Peter C, Huszthy, Helena, Motaln, Krishna M, Talasila, Hrvoje, Miletic, Nadia A, Atai, Rolf, Bjerkvig, Tamara, Lah Turnšek
Publikováno v:
Experimental cell research. 356(1)
Low-grade, pilocytic astrocytomas are treated by resection, but additional therapy is necessary for those tumors with anaplastic features. Arsenic trioxide (As
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::15761e43171a321c6f940b51e460e26d
https://pubmed.ncbi.nlm.nih.gov/28412241
https://pubmed.ncbi.nlm.nih.gov/28412241
Autor:
Hrvoje Miletic, Krishna M. Talasila, Jian Wang, Frits Thorsen, Rolf Bjerkvig, Mathias Hoehn, Thomas Viel, Bernd Neumaier, Parisa Monfared, Alexandra Winkeler, Narve Brekka, Yannic Waerzeggers, Jan F. Jikeli, Heiko Backes, Daniel Stieber, Andreas H. Jacobs, Bertrand Tavitian, Simone P. Niclou
Publikováno v:
Journal of Nuclear Medicine; Vol 53
The hypothesis of this study was that distinct experimental glioblastoma phenotypes resembling human disease can be noninvasively distinguished at various disease stages by imaging in vivo. Methods: Cultured spheroids from 2 human glioblastomas were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2132643215c6b8a43560e08c76579fdb