Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Krishna K. Kolluri"'
Autor:
Robert E. Hynds, Ariana Huebner, David R. Pearce, Mark S. Hill, Ayse U. Akarca, David A. Moore, Sophia Ward, Kate H. C. Gowers, Takahiro Karasaki, Maise Al Bakir, Gareth A. Wilson, Oriol Pich, Carlos Martínez-Ruiz, A. S. Md Mukarram Hossain, Simon P. Pearce, Monica Sivakumar, Assma Ben Aissa, Eva Grönroos, Deepak Chandrasekharan, Krishna K. Kolluri, Rebecca Towns, Kaiwen Wang, Daniel E. Cook, Leticia Bosshard-Carter, Cristina Naceur-Lombardelli, Andrew J. Rowan, Selvaraju Veeriah, Kevin Litchfield, Philip A. J. Crosbie, Caroline Dive, Sergio A. Quezada, Sam M. Janes, Mariam Jamal-Hanjani, Teresa Marafioti, TRACERx consortium, Nicholas McGranahan, Charles Swanton
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Patient-derived xenograft (PDX) models are widely used in cancer research. To investigate the genomic fidelity of non-small cell lung cancer PDX models, we established 48 PDX models from 22 patients enrolled in the TRACERx study. Multi-regio
Externí odkaz:
https://doaj.org/article/15a9cb6171ca46d4a07fbfbe6bf74b76
Autor:
Rahul Y. Mahida, Zhengqiang Yuan, Krishna K. Kolluri, Aaron Scott, Dhruv Parekh, Rowan S. Hardy, Michael A. Matthay, Gavin D. Perkins, Sam M. Janes, David R. Thickett
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
BackgroundHuman bone marrow mesenchymal stem cell (MSC) administration reduces inflammation in pre-clinical models of sepsis and sepsis-related lung injury, however clinical efficacy in patients has not yet been demonstrated. We previously showed tha
Externí odkaz:
https://doaj.org/article/0f8693c2f31c4a3599fce5ef594f00f9
Autor:
P. Stephen Patrick, Krishna K. Kolluri, May Zaw Thin, Adam Edwards, Elizabeth K. Sage, Tom Sanderson, Benjamin D. Weil, John C. Dickson, Mark F. Lythgoe, Mark Lowdell, Sam M. Janes, Tammy L. Kalber
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-12 (2020)
Abstract Background MSCTRAIL is a cell-based therapy consisting of human allogeneic umbilical cord-derived MSCs genetically modified to express the anti-cancer protein TRAIL. Though cell-based therapies are typically designed with a target tissue in
Externí odkaz:
https://doaj.org/article/77b713e5b32c4ca89d12cd9d999e858f
Publikováno v:
Journal of Extracellular Vesicles, Vol 6, Iss 1 (2017)
Extracellular vesicles (EVs) are lipid membrane-enclosed nanoparticles released by cells. They mediate intercellular communication by transferring biological molecules and therefore have potential as innovative drug delivery vehicles. TNF-related apo
Externí odkaz:
https://doaj.org/article/834797eb31d4413ea1d0c91933d38919
Autor:
Elizabeth K. Sage, May Zaw Thin, Tammy L. Kalber, Mark W. Lowdell, Krishna K. Kolluri, Mark F. Lythgoe, Adam Edwards, Benjamin D. Weil, John Dickson, Tom Sanderson, Sam M. Janes, P. Stephen Patrick
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-12 (2020)
Stem Cell Research & Therapy
Stem Cell Research & Therapy
Background MSCTRAIL is a cell-based therapy consisting of human allogeneic umbilical cord-derived MSCs genetically modified to express the anti-cancer protein TRAIL. Though cell-based therapies are typically designed with a target tissue in mind, del
Autor:
Adam Pennycuick, Neelam Kumar, Xidan Zhang, Mary Falzon, Krishna K. Kolluri, Ersilia Nigro, Yuki Ishii, Doraid Alrifai, Khalid Shah, Elaine Borg, Sam M. Janes
Publikováno v:
The Journal of Biological Chemistry
Malignant pleural mesothelioma (MPM) is a rare, aggressive, and incurable cancer arising from the mesothelial lining of the pleura, with few available treatment options. We recently reported that loss of function of the nuclear deubiquitinase BRCA1-a
Autor:
Neelam Kumar, Ersilia Nigro, Sam M. Janes, Adam Pennycuick, Yuki Ishii, Mary Falzon, Khalid Shah, Doraid Alrifai, Elaine Borg, Krishna K. Kolluri
Malignant pleural mesothelioma (MPM) is a rare, aggressive, and incurable cancer arising from the mesothelial lining of the lungs with few treatment options. We recently reported loss of function of the nuclear deubiquitinase BRCA associated protein-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::194f89ba7e05f5ee81fd29e329bf09cc
https://doi.org/10.1101/2020.08.31.274951
https://doi.org/10.1101/2020.08.31.274951
Autor:
Aaron Scott, Gareth G. Lavery, Sam M. Janes, Rahul Y Mahida, Rowan Hardy, David R Thickett, ZhengQiang Yuan, Dhruv Parekh, Krishna K. Kolluri, Sebastian T Lugg
Background: Human bone marrow mesenchymal stem cell (MSC) administration reduces inflammation in pre-clinical models of lung injury, however clinical efficacy in patients with acute respiratory distress syndrome (ARDS) has not been shown. Upregulatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c7878dc8854036fc3c8fbeee0b1bdc6
https://doi.org/10.21203/rs.2.14766/v1
https://doi.org/10.21203/rs.2.14766/v1
Autor:
Stasia Krishtul, Sam M. Janes, Tzila Davidov, Avraham Fridman, Marcelle Machluf, Krishna K. Kolluri, Lior Levy
Publikováno v:
Advanced Functional Materials. 32:2105701
Autor:
Sam M. Janes, Y. Ngai, Martin Forster, Bilyana Popova, Mark W. Lowdell, R. Graham, B. Weil, A. Day, Vitor H. Teixeira, Krishna K. Kolluri, D. Fullen, A. Davies
Publikováno v:
Cytotherapy. 23:S61