Small intestinal microbial dysbiosis underlies symptoms associated with functional gastrointestinal disorders

Autor: George B. Saffouri, Robin R. Shields-Cutler, Jun Chen, Yi Yang, Heather R. Lekatz, Vanessa L. Hale, Janice M. Cho, Eric J. Battaglioli, Yogesh Bhattarai, Kevin J. Thompson, Krishna K. Kalari, Gaurav Behera, Jonathan C. Berry, Stephanie A. Peters, Robin Patel, Audrey N. Schuetz, Jeremiah J. Faith, Michael Camilleri, Justin L. Sonnenburg, Gianrico Farrugia, Jonathan R. Swann, Madhusudan Grover, Dan Knights, Purna C. Kashyap

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)

Small intestinal bacterial overgrowth (SIBO) has been associated with functional gastrointestinal disorders. Here, the authors show that SIBO may be a result of dietary preferences, and patient symptoms correlate with changes in small intestinal micr

Externí odkaz: https://doaj.org/article/32a844355ed94b92862ae083fcfb70df

Pre-treatment peripheral blood immunophenotyping and response to neoadjuvant chemotherapy in operable breast cancer.

Autor: Leon-Ferre RA; Department of Oncology, Mayo Clinic, Rochester, MN, USA. leonferre.roberto@mayo.edu., Whitaker KR; Division of Hematology, Mayo Clinic, Rochester, MN, USA., Suman VJ; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA., Hoskin T; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA., Giridhar KV; Department of Oncology, Mayo Clinic, Rochester, MN, USA., Moore RM; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA., Al-Jarrad A; Division of Hematology, Mayo Clinic, Rochester, MN, USA., McLaughlin SA; Department of Surgery, Mayo Clinic, Jacksonville, FL, USA., Northfelt DW; Division of Hematology and Oncology, Mayo Clinic, Scottsdale, AZ, USA., Hunt KN; Department of Radiology, Mayo Clinic, Rochester, MN, USA., Conners AL; Department of Radiology, Mayo Clinic, Rochester, MN, USA., Moyer A; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA., Carter JM; Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Alberta, Canada., Kalari K; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA., Weinshilboum R; Schulze Center for Novel Therapeutics, Mayo Clinic, Rochester, MN, USA., Wang L; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA., Ingle JN; Department of Oncology, Mayo Clinic, Rochester, MN, USA., Knutson KL; Department of Immunology, Mayo Clinic, Jacksonville, FL, USA., Ansell SM; Division of Hematology, Mayo Clinic, Rochester, MN, USA., Boughey JC; Department of Surgery, Mayo Clinic, Rochester, MN, USA., Goetz MP; Department of Oncology, Mayo Clinic, Rochester, MN, USA., Villasboas JC; Division of Hematology, Mayo Clinic, Rochester, MN, USA.

Publikováno v: Breast cancer research : BCR [Breast Cancer Res] 2024 Jun 10; Vol. 26 (1), pp. 97. Date of Electronic Publication: 2024 Jun 10.

A clinical calculator to predict disease outcomes in women with triple-negative breast cancer.

Autor: Polley MC; Department of Public Health Sciences, University of Chicago, Chicago, IL, USA. mcpolley@uchicago.edu., Leon-Ferre RA; Department of Oncology, Mayo Clinic, Rochester, MN, USA., Leung S; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada., Cheng A; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada., Gao D; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada., Sinnwell J; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA., Liu H; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA., Hillman DW; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA., Eyman-Casey A; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA., Gilbert JA; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA., Negron V; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA., Boughey JC; Department of Surgery, Mayo Clinic, Rochester, MN, USA., Liu MC; Department of Oncology, Mayo Clinic, Rochester, MN, USA., Ingle JN; Department of Oncology, Mayo Clinic, Rochester, MN, USA., Kalari K; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA., Couch F; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA., Carter JM; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA., Visscher DW; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA., Nielsen TO; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada., Goetz MP; Department of Oncology, Mayo Clinic, Rochester, MN, USA.

Publikováno v: Breast cancer research and treatment [Breast Cancer Res Treat] 2021 Feb; Vol. 185 (3), pp. 557-566. Date of Electronic Publication: 2021 Jan 03.

Breast cancer chemoprevention pharmacogenomics: Deep sequencing and functional genomics of the ZNF423 and CTSO genes.

Autor: Liu D; Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN USA., Ho MF; Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN USA., Schaid DJ; Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN USA., Scherer SE; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX USA., Kalari K; Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN USA., Liu M; Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN USA., Biernacka J; Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN USA., Yee V; Department of Biochemistry, Case Western Reserve University, Cleveland, OH USA., Evans J; Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN USA., Carlson E; Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN USA., Goetz MP; Division of Medical Oncology, Mayo Clinic, Rochester, MN USA., Kubo M; RIKEN Center for Integrative Medical Science, Yokohama, Japan., Wickerham DL; Section of Cancer Genetics and Prevention, Allegheny General Hospital and the National Surgical Adjuvant Breast and Bowel Project (NSABP), Pittsburgh, PA USA., Wang L; Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN USA., Ingle JN; Division of Medical Oncology, Mayo Clinic, Rochester, MN USA., Weinshilboum RM; Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN USA.

Publikováno v: NPJ breast cancer [NPJ Breast Cancer] 2017 Aug 21; Vol. 3, pp. 30. Date of Electronic Publication: 2017 Aug 21 (Print Publication: 2017).

IM-TORNADO: a tool for comparison of 16S reads from paired-end libraries.

Autor: Jeraldo P; Department of Surgery, Mayo Clinic, Rochester, Minnesota, United States of America; Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America., Kalari K; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, United States of America., Chen X; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, United States of America., Bhavsar J; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, United States of America., Mangalam A; Department of Immunology, Mayo Clinic, Rochester, Minnesota, United States of America., White B; Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America; Department of Animal Sciences, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America., Nelson H; Department of Surgery, Mayo Clinic, Rochester, Minnesota, United States of America., Kocher JP; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, United States of America., Chia N; Department of Surgery, Mayo Clinic, Rochester, Minnesota, United States of America; Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America; Department of Physiology and Biomedical Engineering, Mayo Clinic College of Medicine, Rochester, Minnesota, United States of America.

Publikováno v: PloS one [PLoS One] 2014 Dec 15; Vol. 9 (12), pp. e114804. Date of Electronic Publication: 2014 Dec 15 (Print Publication: 2014).