Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Krishna G. Upadhya"'
Publikováno v:
Tetrahedron Letters. 36:9277-9280
Summary Carboxylic acids are activated with 1.1′-carbonyldiimidazole in acetonitrile to form N-acylimidazoles which are then treated with per-trimethylsilyl ethers of nucleosides adenosine or cytidine at ambient temperature to generate exclusively
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fbe82ca560eff57468b79246deba646
https://doi.org/10.1016/0040-4039(95)02011-d
https://doi.org/10.1016/0040-4039(95)02011-d
Publikováno v:
Tetrahedron Letters. 33:5033-5036
A 5-carboxyfluorescein (FAM) phosphoramidite reagent has been synthesized for use on automated DNA synthesizers, to prepare fluorescent dye labelled oligonucleotides. Oligonucleotides can be labelIed at any site in a sequence and multiple labelled. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab4fbfd2e1652d392b1f638230ec9d3f
https://doi.org/10.1016/s0040-4039(00)61181-4
https://doi.org/10.1016/s0040-4039(00)61181-4
Publikováno v:
Nucleosides and Nucleotides. 9:649-662
Ribavirin and tiazofurin, two nucleosides of known antiviral activity, have been transformed by previously reported methods to yield several deoxy,epoxy, or dideoxy analogues. The deoxygenated derivatives were evaluated for antiviral activity against
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bce019e1bed05cf89810ae7c1a03211f
https://doi.org/10.1080/07328319008045196
https://doi.org/10.1080/07328319008045196
Publikováno v:
Nucleosides, nucleotidesnucleic acids. 24(5-7)
A new "polystyrene biotin support" has been synthesized for the solid support synthesis of the 3'-biotinylated oligonucleotides. Several oligos were synthesized and were analyzed by the HPLC and Mass Spec. Oligo analysis revealed that the biotin gets
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::588e2298236859dd814660494e522d1c
https://pubmed.ncbi.nlm.nih.gov/16248062
https://pubmed.ncbi.nlm.nih.gov/16248062
Autor:
Joan Hauser, Steve Menchen, Pete Theisen, Scott C. Benson, Krishna G. Upadhya, Paul M. Kenney
Publikováno v:
SPIE Proceedings.
Labeling of DNA with fluorescent reporter is generally accomplished by attaching fluorescent dyes to the 5'-end of primers for PCR based applications, including geno-typing and linkage mapping. Requirements of spectral resolution and chemical stabili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c1bf6aa6389826ee8de6a874d3ad471
https://doi.org/10.1117/12.380498
https://doi.org/10.1117/12.380498
Autor:
A. Constantinescu, Krishna G. Upadhya, Linda G. Lee, Ronald J. Graham, Scott C. Benson, Barnett B. Rosenblum, Jonathan M. Cassel, Sandra L. Spurgeon, C. R. Heiner, Steven M. Menchen
Publikováno v:
Nucleic acids research. 25(14)
We have synthesized a set of four energy transfer dyes and demonstrated their use in automated DNA sequencing. The donor dyes are the 5- or 6-carboxy isomers of 4'-aminomethylfluorescein and the acceptor dyes are a novel set of four 4,7-dichloro-subs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d800854ca46e9b27c9ab5c585b56e6e
https://pubmed.ncbi.nlm.nih.gov/9207029
https://pubmed.ncbi.nlm.nih.gov/9207029
Autor:
Krishna G. Upadhya, Yogesh S. Sanghvi, Ganapathi R. Revankar, Bheemarao G. Ugarkar, Roland K. Robins
Publikováno v:
Nucleic Acids Research. 14:1747-1764
A facile synthesis of 7-amino-5-chloro-3-beta-D-ribofuranosylpyrazolo [4,3-d]pyrimidine (5-chloroformycin A, 6), 7-amino-5-chloro-3-(2-deoxy-beta-D-erythro-pentofuranosyl) pyrazolo [4,3-d]-pyrimidine (5-chloro-2'-deoxyformycin A, 13) and certain rela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a78c362c234e8c8a6bb8580d2da86af5
https://doi.org/10.1093/nar/14.4.1747
https://doi.org/10.1093/nar/14.4.1747
Publikováno v:
Nucleosides and Nucleotides. 5:343-362
The synthesis of several 5′-substituted derivatives of ribavirin (1) and tiazofurin (3) are described. Direct acylation of 1 with the appropriate acyl chloride in pyridine-DMF gave the corresponding 5′-O-acyl derivatives (4a-h). Tosylation of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e1d20c94eeb3c6b781bcd50a1cc94cd
https://doi.org/10.1080/07328318608068678
https://doi.org/10.1080/07328318608068678
Publikováno v:
Archiv der Pharmazie. 313:684-688
Sydnone derivatives with various substituents at C-4 of the phenyl ring and at C-2 of the thiazolyl ring were synthesised and tested for antiinflammatory activity. Five compounds have shown promising results. Synthese und entzundungshemmende Wirkung
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56a45834c860dd56fab3b4b34993c74b
https://doi.org/10.1002/ardp.19803130806
https://doi.org/10.1002/ardp.19803130806
Publikováno v:
Chemischer Informationsdienst. 15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48b1b4f9b43135f6c9824611959f2a38
https://doi.org/10.1002/chin.198449194
https://doi.org/10.1002/chin.198449194