Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Krishan L. Taneja"'
Autor:
Jennifer L. Guerriero, Jia-Ren Lin, Ricardo G. Pastorello, Ziming Du, Yu-An Chen, Madeline G. Townsend, Kenichi Shimada, Melissa E. Hughes, Siyang Ren, Nabihah Tayob, Kelly Zheng, Shaolin Mei, Alyssa Patterson, Krishan L. Taneja, Otto Metzger, Sara M. Tolaney, Nancy U. Lin, Deborah A. Dillon, Stuart J. Schnitt, Peter K. Sorger, Elizabeth A. Mittendorf, Sandro Santagata
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-22 (2024)
Abstract Emerging data suggests that HER2 intratumoral heterogeneity (ITH) is associated with therapy resistance, highlighting the need for new strategies to assess HER2 ITH. A promising approach is leveraging multiplexed tissue analysis techniques s
Externí odkaz:
https://doaj.org/article/3efb1bd4ddfe4838842869755c17c107
Autor:
Krishan L. Taneja
Publikováno v:
BioTechniques, Vol 24, Iss 3, Pp 472-476 (1998)
A labeled peptide nucleic acid (PNA) antisense probe was used to study the spatial distribution of triplet repeats (CTG) in human myotonic dystrophy (DM) cells by high-resolution fluorescence in situ hybridization (FISH). It was found that transcript
Externí odkaz:
https://doaj.org/article/a573f8f1245f460eb874bec07817f0b6
Autor:
M Gabriela, Kuba, Susan C, Lester, Teresa, Bowman, Samantha M, Stokes, Krishan L, Taneja, Judy E, Garber, Deborah A, Dillon
Publikováno v:
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 34(3)
Breast cancer is the most common malignancy in female patients with Li-Fraumeni syndrome (LFS), a rare autosomal dominant hereditary syndrome characterized by germline TP53 mutations. Recent studies have shown that the majority of these tumors are es
Autor:
Andrew M. Bellizzi, Christopher A. French, Stacey E. Mills, Krishan L. Taneja, Edward B. Stelow, Jon C. Aster, Robin D. LeGallo, Jeffery L. Kutok
Publikováno v:
American Journal of Surgical Pathology. 32:828-834
Undifferentiated carcinomas of the upper aerodigestive tract (UCUAT) occur most frequently within the nasopharynx and are most often associated with infection by Epstein-Barr virus (EBV) (WHO undifferentiated nonkeratinizing squamous cell carcinoma).
Publikováno v:
Genes, Chromosomes and Cancer. 30:57-63
In previous studies, we showed that peptide nucleic acid (PNA) probes have significant advantages over conventional synthetic RNA or DNA probes in FISH procedures for detecting telomeric and trinucleotide repeat sequences. Here, we report that direct
Autor:
Robert H. Singer, Long Guang Cao, Krishan L. Taneja, Marty R. Jacobson, Thoru Pederson, Yu-li Wang
Publikováno v:
Journal of Cell Science. 110:829-837
The ribonucleoprotein enzyme RNase P catalyzes the 5′ processing of pre-transfer RNA, and has also recently been implicated in pre-ribosomal RNA processing. In the present investigation, in situ hybridization revealed that RNase P RNA is present th
Autor:
Shailesh M. Shenoy, Robert H. Singer, Krishan L. Taneja, Lawrence M. Lifshitz, Fredric S. Fay
Publikováno v:
Experimental Cell Research. 231:27-37
Digital imaging microscopy was used to analyze the spatial distribution and levels of newly synthesized RNA in relation to steady-state poly(A) RNA and to the splicing factor SC35. Transcription was monitored over time after microinjection of BrUTP a
Publikováno v:
Nature. 372:809-812
IN mammalian nuclei, precursor messenger RNA splicing factors are distributed non-uniformly. Antibodies directed against struc-tural polypeptides of small nuclear ribonucleoprotein particles (snRNPs)1 and some non-snRNP splicing factors2 have shown t
Publikováno v:
The Journal of Cell Biology
Considerable evidence indicates that mRNA associates with structural filaments in the cell (cytoskeleton). This relationship would be an important mechanism to effect mRNA sorting since specific mRNAs could be sequestered at sites within the cell. In
Publikováno v:
The Journal of Cell Biology
We demonstrate that in differentiating myoblasts, the mRNAs encoding two actin isoforms, beta-cytoplasmic, and alpha-cardiac, can occupy different cytoplasmic compartments within the same cytoplasm. beta- actin mRNA is localized to the leading lamell