Zobrazeno 1 - 10
of 208
pro vyhledávání: '"Krish D, Singh"'
Autor:
James B Rowe, Vanessa Raymont, Yun-Ju Cheng, Anna C Nobre, Juliette Helene Lanskey, Ece Kocagoncu, Andrew J Quinn, Melek Karadag, Jemma Pitt, Stephen Lowe, Michael Perkinton, Krish D Singh, Mark Woolrich, Richard N Henson
Publikováno v:
BMJ Open, Vol 12, Iss 12 (2022)
Introduction With the pressing need to develop treatments that slow or stop the progression of Alzheimer’s disease, new tools are needed to reduce clinical trial duration and validate new targets for human therapeutics. Such tools could be derived
Externí odkaz:
https://doaj.org/article/1c3c954621654c85a6664c81f8185711
Autor:
Eirini Messaritaki, Sonya Foley, Simona Schiavi, Lorenzo Magazzini, Bethany Routley, Derek K. Jones, Krish D. Singh
Publikováno v:
Network Neuroscience, Vol 5, Iss 2, Pp 477-504 (2021)
AbstractUnderstanding how human brain microstructure influences functional connectivity is an important endeavor. In this work, magnetic resonance imaging data from 90 healthy participants were used to calculate structural connectivity matrices using
Externí odkaz:
https://doaj.org/article/ec4edac38c3343a89cc4ff9a9b71573f
Autor:
Golnoush Alamian, Tarek Lajnef, Annalisa Pascarella, Jean-Marc Lina, Laura Knight, James Walters, Krish D. Singh, Karim Jerbi
Publikováno v:
Frontiers in Neural Circuits, Vol 16 (2022)
Schizophrenia has a complex etiology and symptomatology that is difficult to untangle. After decades of research, important advancements toward a central biomarker are still lacking. One of the missing pieces is a better understanding of how non-line
Externí odkaz:
https://doaj.org/article/e0976062fa394ad79bc19819afe0073d
Autor:
Neeraj Saxena, Suresh D. Muthukumaraswamy, Lewys Richmond, Adele Babic, Krish D. Singh, Judith E. Hall, Richard G. Wise, Alexander D. Shaw
Publikováno v:
NeuroImage, Vol 245, Iss , Pp 118659- (2021)
Studying changes in cortical oscillations can help elucidate the mechanistic link between receptor physiology and the clinical effects of anaesthetic drugs. Propofol, a GABA-ergic drug produces divergent effects on visual cortical activity: increasin
Externí odkaz:
https://doaj.org/article/2b1fe888dbea4781a67e362ad34197ba
Autor:
Megan Godfrey, Krish D. Singh
Publikováno v:
NeuroImage, Vol 226, Iss , Pp 117551- (2021)
Recent studies have shown how MEG can reveal spatial patterns of functional connectivity using frequency-specific oscillatory coupling measures and that these may be modified in disease. However, there is a need to understand both how repeatable thes
Externí odkaz:
https://doaj.org/article/6242e9d1ec704bfcb362f5c18e90f662
Autor:
Lauren E. Gascoyne, Matthew J. Brookes, Mohanbabu Rathnaiah, Mohammad Zia Ul Haq Katshu, Loes Koelewijn, Gemma Williams, Jyothika Kumar, James T.R. Walters, Zelekha A. Seedat, Lena Palaniyappan, J.F. William Deakin, Krish D. Singh, Peter F. Liddle, Peter G. Morris
Publikováno v:
NeuroImage: Clinical, Vol 29, Iss , Pp 102524- (2021)
Magnetoencephalography (MEG) measures magnetic fields generated by synchronised neural current flow and provides direct inference on brain electrophysiology and connectivity, with high spatial and temporal resolution. The movement-related beta decrea
Externí odkaz:
https://doaj.org/article/c2366ba9c9934b14932231342cbbc0a0
Autor:
Alexander D Shaw, Suresh D Muthukumaraswamy, Neeraj Saxena, Rachael L Sumner, Natalie E Adams, Rosalyn J Moran, Krish D Singh
Publikováno v:
NeuroImage, Vol 221, Iss , Pp 117189- (2020)
Cortical recordings of task-induced oscillations following subanaesthetic ketamine administration demonstrate alterations in amplitude, including increases at high-frequencies (gamma) and reductions at low frequencies (theta, alpha). To investigate t
Externí odkaz:
https://doaj.org/article/acb3b55db3c64cb18b8d1ef0af97b169
Autor:
Golnoush Alamian, Annalisa Pascarella, Tarek Lajnef, Laura Knight, James Walters, Krish D. Singh, Karim Jerbi
Publikováno v:
NeuroImage: Clinical, Vol 28, Iss , Pp 102485- (2020)
Current theories of schizophrenia emphasize the role of altered information integration as the core dysfunction of this illness. While ample neuroimaging evidence for such accounts comes from investigations of spatial connectivity, understanding temp
Externí odkaz:
https://doaj.org/article/5e7ee103b1d14564af4be29b091c95e1
Autor:
Gavin Perry, Nathan W Taylor, Philippa C H Bothwell, Colette C Milbourn, Georgina Powell, Krish D Singh
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0243237 (2020)
It has recently been demonstrated through invasive electrophysiology that visual stimulation with extended patches of uniform colour generates pronounced gamma oscillations in the visual cortex of both macaques and humans. In this study we sought to
Externí odkaz:
https://doaj.org/article/8c77602c508e49bfb21a16dbf4fdcd1b
Autor:
Nicolaas A. J. Puts, Richard A. E. Edden, Suresh Muthukumaraswamy, Krish D. Singh, David J. McGonigle
Publikováno v:
Neural Plasticity, Vol 2019 (2019)
Prolonged exposure to afferent stimulation (“adaptation”) can cause profound short-term changes in the responsiveness of cortical sensory neurons. While several models have been proposed that link adaptation to single-neuron dynamics, including G
Externí odkaz:
https://doaj.org/article/bf74ca462dc24a86a7a0e3df20770b75