Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Krish Chandrasekaran"'
Publikováno v:
Neurobiology of Disease, Vol 64, Iss , Pp 118-130 (2014)
Mitochondrial degeneration is considered to play an important role in the development of diabetic peripheral neuropathy in humans. Mitochondrial degeneration and the corresponding protein regulation associated with the degeneration were studied in an
Externí odkaz:
https://doaj.org/article/fc437358c138484a8258a7a2a2b53b0e
Autor:
Jennifer O’Brien, Peter Niehaus, Juliana Remark, Mohammad Salimian, Yanni Kevas, Samuel Rubin, Tibor Kristian, Krish Chandrasekaran, Catherine Pei-Ju Lu, James W. Russell, Cheng-Ying Ho
Publikováno v:
bioRxiv
Diabetic neuropathy (DN) is a debilitating disorder characterized by mechanical allodynia and sensory loss. It has traditionally been considered a small-fiber neuropathy, defined by the loss of free nerve endings in the epidermis. Free nerve endings,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54cc970df06af3ab9202622846be881a
https://doi.org/10.1101/2023.01.24.523981
https://doi.org/10.1101/2023.01.24.523981
Publikováno v:
Contemporary Diabetes ISBN: 9783031156120
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::adf809a7cf40fc8ffea269c57de6382b
https://doi.org/10.1007/978-3-031-15613-7_17
https://doi.org/10.1007/978-3-031-15613-7_17
Autor:
Krish Chandrasekaran, Neda Najimi, Avinash R. Sagi, Sushuma Yarlagadda, Mohammad Salimian, Muhammed Ikbal Arvas, Ahmad F. Hedayat, Yanni Kevas, Anand Kadakia, James W. Russell
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 9; Pages: 4887
Axon degeneration in diabetic peripheral neuropathy (DPN) is associated with impaired NAD+ metabolism. We tested whether the administration of NAD+ precursors, nicotinamide mononucleotide (NMN) or nicotinamide riboside (NR), prevents DPN in models of
Publikováno v:
Microvascular Disease in Diabetes
Autor:
Krish, Chandrasekaran, Neda, Najimi, Avinash R, Sagi, Sushuma, Yarlagadda, Mohammad, Salimian, Muhammed Ikbal, Arvas, Ahmad F, Hedayat, Yanni, Kevas, Anand, Kadakia, James W, Russell
Publikováno v:
International journal of molecular sciences. 23(9)
Axon degeneration in diabetic peripheral neuropathy (DPN) is associated with impaired NAD
Autor:
Gulcin Akinci, Henning Andersen, Andrew J.M. Boulton, Frank Lee Bowling, Vera Bril, Nigel A. Calcutt, Brian C. Callaghan, Josie Carmichael, Krish Chandrasekaran, Joseph Colombo, Niels Ejskjaer, Hassan Fadavi, Eva L. Feldman, Keeley Jane Foley, Gary Gallagher, Hanna Harno, Fukashi Ishibashi, Páll Karlsson, Venu Kavarthapu, Joyce Lim, Andrew G. Marshall, Anne Marshall, Deepak Menon, Kalliopi Pafili, Nikolaos Papanas, Amanda C. Peltier, Brendan N. Putko, Beatriz Rodríguez-Sánchez, Johan Røikjer, Milla Rosengård-Bärlund, James W. Russell, Masha G. Savelieff, Dinesh Selvarajah, Angela C. Shore, Alan Sinclair, Anders Stouge, Mitra Tavakoli, Solomon Tesfaye, Prashanth R.J. Vas, Soroku Yagihashi, Dilek Gogas Yavuz, Mark Yorek, Lindsay A. Zilliox, Douglas W. Zochodne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54d0b9bbf41015b5c9cdf2438860d178
https://doi.org/10.1016/b978-0-12-820669-0.00030-x
https://doi.org/10.1016/b978-0-12-820669-0.00030-x
Autor:
Muhammed Ikbal Arvas, James W. Russell, Mohammad Salimian, Tibor Kristian, Rao P. Gullapalli, Su Xu, Krish Chandrasekaran, Sujal Singh, Joungil Choi
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3756, p 3756 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 11
International Journal of Molecular Sciences
Volume 21
Issue 11
Diabetes predisposes to cognitive decline leading to dementia and is associated with decreased brain NAD+ levels. This has triggered an intense interest in boosting nicotinamide adenine dinucleotide (NAD+) levels to prevent dementia. We tested if the
Autor:
Anjaneyulu Muragundla, Cheng-Ying Ho, Krish Chandrasekaran, James W. Russell, Joungil Choi, Neda Najimi, Gary Fiskum, Anmol Singh, Steven L. Britton, Tyler G. Demarest, Pranith Kumar, Lauren G. Koch, Avinash Rao Sagi
Publikováno v:
Annals of Clinical and Translational Neurology
Objectives There is a critical need to develop effective treatments for diabetic neuropathy. This study determined if a selective mGluR2/3 receptor agonist prevented or treated experimental diabetic peripheral neuropathy (DPN) through glutamate recyc