Zobrazeno 1 - 10
of 563
pro vyhledávání: '"Kris Thielemans"'
Autor:
Laura Marcos-Villar, Beatriz Perdiguero, Shubaash Anthiya, Mireya L. Borrajo, Gustavo Lou, Lorenzo Franceschini, Ignasi Esteban, Pedro J. Sánchez-Cordón, Carmen Zamora, Carlos Óscar S. Sorzano, Luis Jordá, Laia Codó, Josep L. Gelpí, Marta Sisteré-Oró, Andreas Meyerhans, Kris Thielemans, Francisco Martínez-Jiménez, Núria López-Bigas, Felipe García, María J. Alonso, Montserrat Plana, Mariano Esteban, Carmen Elena Gómez
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-15 (2024)
Abstract Vaccines based on mRNA technology have revolutionized the field. In fact, lipid nanoparticles (LNP) formulated with mRNA are the preferential vaccine platform used in the fight against SARS-CoV-2 infection, with wider application against oth
Externí odkaz:
https://doaj.org/article/9161a691dc534dadb8067291bb76b860
Autor:
Laura Marcos-Villar, Beatriz Perdiguero, María López-Bravo, Carmen Zamora, Laura Sin, Enrique Álvarez, Carlos Óscar S. Sorzano, Pedro J. Sánchez-Cordón, José M. Casasnovas, David Astorgano, Juan García-Arriaza, Shubaash Anthiya, Mireya L. Borrajo, Gustavo Lou, Belén Cuesta, Lorenzo Franceschini, Josep L. Gelpí, Kris Thielemans, Marta Sisteré-Oró, Andreas Meyerhans, Felipe García, Ignasi Esteban, Núria López-Bigas, Montserrat Plana, María J. Alonso, Mariano Esteban, Carmen Elena Gómez
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
Despite the high efficiency of current SARS-CoV-2 mRNA vaccines in reducing COVID-19 morbidity and mortality, waning immunity and the emergence of resistant variants underscore the need for novel vaccination strategies. This study explores a heterolo
Externí odkaz:
https://doaj.org/article/249ddc44798e493a9e82b35d7493dba3
Autor:
Francesca Leek, Cameron Anderson, Andrew P. Robinson, Robert M. Moss, Joanna C. Porter, Helen S. Garthwaite, Ashley M. Groves, Brian F. Hutton, Kris Thielemans
Publikováno v:
EJNMMI Physics, Vol 10, Iss 1, Pp 1-22 (2023)
Abstract Background Increased pulmonary $$^{18}{}$$ 18 F-FDG metabolism in patients with idiopathic pulmonary fibrosis, and other forms of diffuse parenchymal lung disease, can predict measurements of health and lung physiology. To improve PET quanti
Externí odkaz:
https://doaj.org/article/94f82b76de804200aa683314151cf6f6
Autor:
Laura Marcos-Villar, Beatriz Perdiguero, Shubaash Anthiya, Mireya L. Borrajo, Gustavo Lou, Lorenzo Franceschini, Ignasi Esteban, Pedro J. Sánchez-Cordón, Carmen Zamora, Carlos Óscar S. Sorzano, Luis Jordá, Laia Codó, Josep L. Gelpí, Marta Sisteré-Oró, Andreas Meyerhans, Kris Thielemans, Francisco Martínez-Jiménez, Núria López-Bigas, Felipe García, María J. Alonso, Montserrat Plana, Mariano Esteban, Carmen Elena Gómez
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/65c430fb91f54fc0aada194799ba02ca
Autor:
Daniel Deidda, Ana M. Denis-Bacelar, Andrew J. Fenwick, Kelley M. Ferreira, Warda Heetun, Brian F. Hutton, Daniel R. McGowan, Andrew P. Robinson, James Scuffham, Kris Thielemans, Robert Twyman
Publikováno v:
EJNMMI Physics, Vol 10, Iss 1, Pp 1-16 (2023)
Abstract Purpose Nuclear medicine imaging modalities like computed tomography (CT), single photon emission CT (SPECT) and positron emission tomography (PET) are employed in the field of theranostics to estimate and plan the dose delivered to tumors a
Externí odkaz:
https://doaj.org/article/a47d0f95ac144badb28de0725230005b
Autor:
Georg Schramm, Kris Thielemans
Publikováno v:
Frontiers in Nuclear Medicine, Vol 3 (2024)
In this article, we introduce parallelproj, a novel open-source framework designed for efficient parallel computation of projections in tomography leveraging either multiple CPU cores or GPUs. This framework efficiently implements forward and back pr
Externí odkaz:
https://doaj.org/article/5855773a98f64a3a9f474a295ee385ad
Autor:
Rebecca Gillen, Kjell Erlandsson, Ana M. Denis-Bacelar, Kris Thielemans, Brian F. Hutton, Sarah J. McQuaid
Publikováno v:
EJNMMI Physics, Vol 9, Iss 1, Pp 1-22 (2022)
Abstract Background Currently, there is no consensus on the optimal partial volume correction (PVC) algorithm for oncology imaging. Several existing PVC methods require knowledge of the reconstructed resolution, usually as the point spread function (
Externí odkaz:
https://doaj.org/article/acc08dabf11d4315a9b15086c1d637cd
Autor:
Ignasi Esteban, Carmen Pastor-Quiñones, Lorena Usero, Elena Aurrecoechea, Lorenzo Franceschini, Arthur Esprit, Josep Lluís Gelpí, Francisco Martínez-Jiménez, Núria López-Bigas, Karine Breckpot, Kris Thielemans, Lorna Leal, Carmen Elena Gómez, Marta Sisteré-Oró, Andreas Meyerhans, Mariano Esteban, María José Alonso, Felipe García, Montserrat Plana
Publikováno v:
Vaccines, Vol 12, Iss 1, p 15 (2023)
The COVID-19 pandemic has brought significant changes and advances in the field of vaccination, including the implementation and widespread use of encapsidated mRNA vaccines in general healthcare practice. Here, we present two new mRNAs expressing an
Externí odkaz:
https://doaj.org/article/5049aac8017e41528739adfc92cee953
Autor:
Matthew Strugari, Carles Falcon, Kjell Erlandsson, Brian F. Hutton, Kimberly Brewer, Kris Thielemans
Publikováno v:
Frontiers in Nuclear Medicine, Vol 3 (2023)
Single-photon emission computed tomography (SPECT) systems with pinhole collimators are becoming increasingly important in clinical and preclinical nuclear medicine investigations as they can provide a superior resolution-sensitivity trade-off compar
Externí odkaz:
https://doaj.org/article/a809d281e0a4417ebae92cac3e5734f2
Autor:
Wout de Mey, Hanne Locy, Kirsten De Ridder, Phaedra De Schrijver, Dorien Autaers, Asma Lakdimi, Arthur Esprit, Lorenzo Franceschini, Kris Thielemans, Magali Verdonck, Karine Breckpot
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Dendritic cell (DC)-maturation stimuli determine the potency of these antigen-presenting cells and, therefore, the quality of the T-cell response. Here we describe that the maturation of DCs via TriMix mRNA, encoding CD40 ligand, a constitutively act
Externí odkaz:
https://doaj.org/article/e9862a7e26b048f78a167d94669c00a0