Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Kris Leslie"'
Autor:
Andrea Conidi, Veronique van den Berghe, Kris Leslie, Agata Stryjewska, Hua Xue, Ye-Guang Chen, Eve Seuntjens, Danny Huylebroeck
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76733 (2013)
The zinc finger transcription factor Smad-interacting protein-1 (Sip1; Zeb2, Zfhx1b) plays an important role during vertebrate embryogenesis in various tissues and differentiating cell types, and during tumorigenesis. Previous biochemical analysis su
Externí odkaz:
https://doaj.org/article/a38d0dea782f40bb94b8e06367a20dfe
Autor:
Kris Leslie, Eerik Aunin, Yuko Fukata, Masahiko Watanabe, Martine Jaegle, Masaki Fukata, Dies Meijer, Siska Driegen, Linde Kegel
Publikováno v:
Development, 141(8), 1749-1756. Company of Biologists Ltd
Development; Vol 141
Development; Vol 141
The cellular interactions that drive the formation and maintenance of the insulating myelin sheath around axons are only partially understood. Leucine-rich glioma-inactivated (LGI) proteins play important roles in nervous system development and mutat
Autor:
Alastair R. Hawkins, C.E. Nichols, David K. Stammers, Simon Cocklin, Jingshan Ren, A. Dodds, Kris Leslie, Heather K. Lamb
NmrA is a negative transcriptional regulator involved in the post-translational modulation of the GATA-type transcription factor AreA, forming part of a system controlling nitrogen metabolite repression in various fungi. X-ray structures of two NmrA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::718a9e48cef112363aecb4ff0c85e080
https://ora.ox.ac.uk/objects/uuid:d9424090-00c9-4d58-87a5-a8d8b279ce74
https://ora.ox.ac.uk/objects/uuid:d9424090-00c9-4d58-87a5-a8d8b279ce74
The negative transcriptional regulator NmrA discriminates between oxidized and reduced dinucleotides
Autor:
Kris Leslie, Paul Thompson, Alan Cooper, Margaret Nutley, Alastair R. Hawkins, A. Dodds, David K. Stammers, Christopher L. Johnson, Heather K. Lamb
NmrA, a transcription repressor involved in the regulation of nitrogen metabolism in Aspergillus nidulans,is a member of the short-chain dehydrogenase reductase superfamily. Isothermal titration calorimetry and differential scanning calorimetry have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8799892ffbf4622153a0783addc1a50c
https://ora.ox.ac.uk/objects/uuid:883dcf17-13a6-41a3-91d3-833df6971a11
https://ora.ox.ac.uk/objects/uuid:883dcf17-13a6-41a3-91d3-833df6971a11
Autor:
Kris Leslie, Dick H. W. Dekkers, Luca Signorile, Niels Galjart, Joyce H.G. Lebbink, Nuo Yu, Sophie Ottema, Sreya Basu, Jeroen Demmers, Ihor Smal
Publikováno v:
Current Biology, 26(13), 1728-1736. Cell Press
The microtubule (MT) cytoskeleton forms a dynamic filamentous network that is essential for many processes, including mitosis, cell polarity and shape, neurite outgrowth and migration, and ciliogenesis [1, 2]. MTs are built up of a/beta-tubulin heter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48cde25087524035161a05f750786ee3
https://pure.eur.nl/en/publications/ec7cca30-df85-4cef-9475-58796dd9b740
https://pure.eur.nl/en/publications/ec7cca30-df85-4cef-9475-58796dd9b740
Autor:
Alastair R. Hawkins, Jingshan Ren, Kris Leslie, David K. Stammers, B. Dhaliwal, C.E. Nichols, Ian G. Charles, Michael Lockyer
Publikováno v:
Journal of Molecular Biology. 343:533-546
Dehydroquinate synthase (DHQS) is a potential target for the development of novel broad-spectrum antimicrobial drugs, active against both prokaryotes and lower eukaryotes. Structures have been reported for Aspergillus nidulans DHQS (AnDHQS) in comple
Autor:
Kris Leslie, Alan Wright, Louise E. Bird, Jingshan Ren, B Degrève, Jan Balzarini, David K. Stammers
Publikováno v:
Journal of Biological Chemistry. 278:24680-24687
Herpes virus thymidine kinases are responsible for the activation of nucleoside antiviral drugs including (E)-5-(2-bromovinyl)-2'-deoxyuridine. Such viral thymidine kinases (tk), beside having a broader substrate specificity compared with host cell e
Autor:
Kris Leslie, Keith R. Fox
Publikováno v:
Biochemistry. 41:3484-3497
We have examined the interaction of Hoechst 33258 and echinomycin with nucleosomal DNA fragments which contain isolated ligand binding sites. A 145 base pair fragment was prepared on the basis of the sequence of tyrT DNA, which contained no CpG or (A
Autor:
Kris, Leslie, Niels, Galjart
Publikováno v:
Methods in cell biology. 115
Microtubule (MT) plus-end-tracking proteins (+TIPs) specifically associate with the plus ends of growing MTs, thereby determining, in many different ways, the dynamic behavior of the MTs. Over the past years, a variety of fluorescently tagged +TIPs h
Autor:
Kris Leslie, Niels Galjart
Microtubule (MT) plus-end-tracking proteins (+ TIPs) specifically associate with the plus ends of growing MTs, thereby determining, in many different ways, the dynamic behavior of the MTs. Over the past years, a variety of fluorescently tagged + TIPs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ea6833bbd83383cdd28afc9941c2704
https://doi.org/10.1016/b978-0-12-407757-7.00008-6
https://doi.org/10.1016/b978-0-12-407757-7.00008-6