Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Kris Lambert-Emo"'
Autor:
Emma C. Reilly, Mike Sportiello, Kris Lambert Emo, Andrea M. Amitrano, Rakshanda Jha, Ashwin B. R. Kumar, Nathan G. Laniewski, Hongmei Yang, Minsoo Kim, David J. Topham
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
CD8 T cell memory offers critical antiviral protection, even in the absence of neutralizing antibodies. The paradigm is that CD8 T cell memory within the lung tissue consists of a mix of circulating TEM cells and non-circulating TRM cells. However, b
Externí odkaz:
https://doaj.org/article/7b93e7b976014f638ba3b9ee4445492d
Autor:
Mike Sportiello, Alexis Poindexter, Emma C. Reilly, Adam Geber, Kris Lambert Emo, Taylor N. Jones, David J. Topham
Tissue-resident memory CD8 T cells (TRM) principally reside in peripheral non-lymphoid tissues such as lung and skin and confer protection against a variety of illnesses ranging from infections to cancers. The functions of different memory CD8 T cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82ed2514ea040f2f9690addc89a43525
https://doi.org/10.1101/2022.09.21.508875
https://doi.org/10.1101/2022.09.21.508875
Publikováno v:
Pathogens, Vol 8, Iss 4, p 196 (2019)
Tissue resident memory (TRM) CD8 T cells comprise a memory population that forms in peripheral, non-lymphoid tissues after an infection that does not recirculate into the bloodstream or other tissues. TRM cells often recognize conserved peptide epito
Externí odkaz:
https://doaj.org/article/99e3f1068f694fad88c9bb801895ecb6
Autor:
Mike Sportiello, Adam Geber, Rohith Palli, A Karim Embong, Nathan G. Laniewski, Emma C. Reilly, Kris Lambert Emo, David J. Topham
BackgroundMany tools exist to perform a rigorous pathway analysis, though traditional gene set enrichment analysis remains among the most common. While useful for many applications, one common situation where it is less so is the metabolic profiling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7108a660d8a5abfa95c138af974dc5b
https://doi.org/10.1101/2022.03.15.484417
https://doi.org/10.1101/2022.03.15.484417
Autor:
Kris Lambert Emo, Young-Min Hyun, Emma Reilly, Christopher Barilla, Scott Gerber, Deborah Fowell, Minsoo Kim, David J Topham
Publikováno v:
PLoS Pathogens, Vol 12, Iss 9, p e1005881 (2016)
During a primary influenza infection, cytotoxic CD8+ T cells need to infiltrate the infected airways and engage virus-infected epithelial cells. The factors that regulate T cell motility in the infected airway tissue are not well known. To more preci
Externí odkaz:
https://doaj.org/article/97fe2bc3712f4329b72b48d6946d6711
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164247 (2016)
After disease resolution, a small subset of influenza specific CD8+ T cells can remain in the airways of the lung as a tissue resident memory population (TRM). These cells are critical for protection from subsequent infections with heterosubtypic inf
Externí odkaz:
https://doaj.org/article/96172128b25645eda5ce06fb77ab1484
Autor:
David J. Topham, Emma C. Reilly, Patrick J. Buckley, Nicholas S. Reilly, Kris Lambert Emo, Francisco A. Chaves, Patrick W. Oakes, Ian Smith, Hongmei Yang
Publikováno v:
Proceedings of the National Academy of Sciences. 117:12306-12314
Tissue-resident memory CD8 T (T RM ) cells are a unique immune memory subset that develops and remains in peripheral tissues at the site of infection, providing future host resistance upon reexposure to that pathogen. In the pulmonary system, T RM ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00617ecdf390078df61cc93dda5bfd27
https://doi.org/10.1073/pnas.1915681117
https://doi.org/10.1073/pnas.1915681117
Autor:
Michael John Sportiello, Adam Geber, Alexis Poindexter, Emma C Reilly, Kris Lambert Emo, David J Topham
Publikováno v:
The Journal of Immunology. 208:114.08-114.08
Tissue resident memory CD8 T cells (TRM) protect against infections. In the lungs, TRM offer critical protection against influenza. Skin TRM display a unique metabolic profile compared to other memory cell subsets. They undergo enhanced fatty acid ox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ceda2c518af20a5e841a68591fbc585f
https://doi.org/10.4049/jimmunol.208.supp.114.08
https://doi.org/10.4049/jimmunol.208.supp.114.08
Autor:
Emma C, Reilly, Kris, Lambert Emo, Patrick M, Buckley, Nicholas S, Reilly, Ian, Smith, Francisco A, Chaves, Hongmei, Yang, Patrick W, Oakes, David J, Topham
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Current influenza vaccination strategies require annual immunizations, with fairly low efficacy rates. One technique to improve protection against a greater breadth of influenza viruses is to elicit broadly cross-reactive cell-mediated i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::583984e4e44079074f4a6f4359e55e72
https://pubmed.ncbi.nlm.nih.gov/32439709
https://pubmed.ncbi.nlm.nih.gov/32439709
Autor:
Patrick W. Oakes, Francisco A. Chaves, David J. Topham, Emma C. Reilly, Hongmei Yang, Patrick J. Buckley, Kris Lambert Emo, Nicholas S. Reilly
Tissue resident memory CD8 T (TRM) cells are a unique immune memory subset that develops and remains in peripheral tissues at the site of infection, providing future host resistance upon re-exposure to that pathogen. In the pulmonary system, TRM are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::519cec3d60b9f6edd95d8c1c99707076