Zobrazeno 1 - 10
of 553
pro vyhledávání: '"Kris Gevaert"'
Autor:
Diego Fernando Garcia-del Rio, Mehdi Derhourhi, Amelie Bonnefond, Sébastien Leblanc, Noé Guilloy, Xavier Roucou, Sven Eyckerman, Kris Gevaert, Michel Salzet, Tristan Cardon
Publikováno v:
Cell Death and Disease, Vol 15, Iss 9, Pp 1-14 (2024)
Abstract Proteogenomics is becoming a powerful tool in personalized medicine by linking genomics, transcriptomics and mass spectrometry (MS)-based proteomics. Due to increasing evidence of alternative open reading frame-encoded proteins (AltProts), p
Externí odkaz:
https://doaj.org/article/8a1299b057b7485c8801accffa45b457
Autor:
Chen Liu, Ioannis H. Hatzianestis, Thorsten Pfirrmann, Salim H. Reza, Elena A. Minina, Ali Moazzami, Simon Stael, Emilio Gutierrez–Beltran, Eugenia Pitsili, Peter Dörmann, Sabine D’Andrea, Kris Gevaert, Francisco Romero–Campero, Pingtao Ding, Moritz K. Nowack, Frank Van Breusegem, Jonathan D. G. Jones, Peter V. Bozhkov, Panagiotis N. Moschou
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract To survive extreme desiccation, seeds enter a period of quiescence that can last millennia. Seed quiescence involves the accumulation of protective storage proteins and lipids through unknown adjustments in protein homeostasis (proteostasis)
Externí odkaz:
https://doaj.org/article/5b27e89baa844c59862769eb8a6a4ffe
Publikováno v:
BMC Plant Biology, Vol 24, Iss 1, Pp 1-17 (2024)
Abstract Background European beech (Fagus sylvatica L.) trees produce seeds irregularly; therefore, it is necessary to store beech seeds for forestation. Despite the acquisition of desiccation tolerance during development, beech seeds are classified
Externí odkaz:
https://doaj.org/article/4e66483150cb4975a058a8bda636f19b
Autor:
Amber Lampens, Michiel Vandecasteele, Marjon Braem, Viktor Devlieghere, Judith Van Dingenen, Kris Gevaert, Sofie Goormachtig
Publikováno v:
Journal of Plant Interactions, Vol 19, Iss 1 (2024)
ABSTRACTPlants express an array of receptor-like kinases (RLKs) to control development and communicate with their environment. Many RLKs are uncharacterized and some of them are expected to regulate plant responses to plant growth-promoting rhizobact
Externí odkaz:
https://doaj.org/article/48629f9b48ac46ee81608875a8081e65
Autor:
Marta Surbek, Tessa Van de Steene, Attila Placido Sachslehner, Bahar Golabi, Johannes Griss, Sven Eyckerman, Kris Gevaert, Leopold Eckhart
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Transglutaminase 1 (TGM1) plays an essential role in skin barrier formation by cross-linking proteins in differentiated keratinocytes. Here, we established a protocol for the antibody-dependent detection of TGM1 protein and the parallel dete
Externí odkaz:
https://doaj.org/article/e17a93f2ae7644e1888d6ca051394575
Autor:
Tine Claeys, Tim Van Den Bossche, Yasset Perez-Riverol, Kris Gevaert, Juan Antonio Vizcaíno, Lennart Martens
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-4 (2023)
Abstract Public proteomics data often lack essential metadata, limiting its potential. To address this, we present lesSDRF, a tool to simplify the process of metadata annotation, thereby ensuring that data leave a lasting, impactful legacy well beyon
Externí odkaz:
https://doaj.org/article/1cf4c9ccda994c42a17b648c7fcf428c
Autor:
Sylvia Varland, Rui Duarte Silva, Ine Kjosås, Alexandra Faustino, Annelies Bogaert, Maximilian Billmann, Hadi Boukhatmi, Barbara Kellen, Michael Costanzo, Adrian Drazic, Camilla Osberg, Katherine Chan, Xiang Zhang, Amy Hin Yan Tong, Simonetta Andreazza, Juliette J. Lee, Lyudmila Nedyalkova, Matej Ušaj, Alexander J. Whitworth, Brenda J. Andrews, Jason Moffat, Chad L. Myers, Kris Gevaert, Charles Boone, Rui Gonçalo Martinho, Thomas Arnesen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-27 (2023)
Abstract Most eukaryotic proteins are N-terminally acetylated, but the functional impact on a global scale has remained obscure. Using genome-wide CRISPR knockout screens in human cells, we reveal a strong genetic dependency between a major N-termina
Externí odkaz:
https://doaj.org/article/d00c6a73922e4ae69223e5ddad630fd5
Autor:
Elly De Vlieghere, Koen Van de Vijver, Eva Blondeel, Nathan Carpentier, Rouba Ghobeira, Jarne Pauwels, Sebastian Riemann, Manon Minsart, Charlotte Fieuws, Johanna Mestach, Ans Baeyens, Nathalie De Geyter, Charlotte Debbaut, Hannelore Denys, Benedicte Descamps, Kathleen Claes, Anne Vral, Jo Van Dorpe, Kris Gevaert, Bruno G. De Geest, Wim Ceelen, Sandra Van Vlierberghe, Olivier De Wever
Publikováno v:
Biomaterials Research, Vol 27, Iss 1, Pp 1-18 (2023)
Abstract Background Long-term drug evaluation heavily relies upon rodent models. Drug discovery methods to reduce animal models in oncology may include three-dimensional (3D) cellular systems that take into account tumor microenvironment (TME) cell t
Externí odkaz:
https://doaj.org/article/3e5a307685aa4c44b056bfedd46942cf
Autor:
Livija Tušar, Jure Loboda, Francis Impens, Piotr Sosnowski, Emmy Van Quickelberghe, Robert Vidmar, Hans Demol, Koen Sedeyn, Xavier Saelens, Matej Vizovišek, Marko Mihelič, Marko Fonović, Jaka Horvat, Gregor Kosec, Boris Turk, Kris Gevaert, Dušan Turk
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-15 (2023)
Abstract Addressing the elusive specificity of cysteine cathepsins, which in contrast to caspases and trypsin-like proteases lack strict specificity determining P1 pocket, calls for innovative approaches. Proteomic analysis of cell lysates with human
Externí odkaz:
https://doaj.org/article/ca692483d89a43aea2681a5be3fe722b
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-12 (2023)
Abstract Heparan sulfates (HS) proteoglycans are commonly found on the cell surface and mediate many processes. Binding of HS ligands is determined by the sulfation code on the HS chain that can be N-/2-O/6-O- or 3-O-sulfated, generating heterogenous
Externí odkaz:
https://doaj.org/article/fd58fc4c6f934d1582988d774eef5901