Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Kris, Barreto"'
Autor:
Wendy Bernhard, Kris Barreto, Darien Toledo, Ayman El-Sayed, Kimberly A. Jett, Angel Casaco, Humphrey Fonge, C. Ronald Geyer
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Molecular-targeted imaging probes can be used with a variety of imaging modalities to detect diseased tissues and guide their removal. EGFR is a useful biomarker for a variety of cancers, because it is expressed at high levels relative to no
Externí odkaz:
https://doaj.org/article/bed93400588348b38db2a18420019388
Autor:
Kimberly A. Jett, Zakery N. Baker, Amzad Hossain, Aren Boulet, Paul A. Cobine, Sagnika Ghosh, Philip Ng, Orhan Yilmaz, Kris Barreto, John DeCoteau, Karen Mochoruk, George N. Ioannou, Christopher Savard, Sai Yuan, Osama H.M.H. Abdalla, Christopher Lowden, Byung-Eun Kim, Hai-Ying Mary Cheng, Brendan J. Battersby, Vishal M. Gohil, Scot C. Leary
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 1 (2023)
Signaling circuits crucial to systemic physiology are widespread, yet uncovering their molecular underpinnings remains a barrier to understanding the etiology of many metabolic disorders. Here, we identified a copper-linked signaling circuit activate
Externí odkaz:
https://doaj.org/article/018c1e9c28eb4a92a02a5abcb7afd106
Autor:
Bharathikumar Vellalore Maruthachalam, Kris Barreto, Daniel Hogan, Anthony Kusalik, Clarence Ronald Geyer
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Synthetic antibodies have been engineered against a wide variety of antigens with desirable biophysical, biochemical, and pharmacological properties. Here, we describe the generation and characterization of synthetic antigen-binding fragments (Fabs)
Externí odkaz:
https://doaj.org/article/3c54628abc1d47bcb5c7eb052f513bb4
Autor:
Wendy Bernhard, Kris Barreto, Ayman El-Sayed, Carolina Gonzalez, Raja Solomon Viswas, Darien Toledo, Angel Casaco, John DeCoteau, Humphrey Fonge, Clarence Ronald Geyer
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-13 (2021)
Abstract Background Epidermal growth factor receptor (EGFR) is a target for cancer therapy as it is overexpressed in a wide variety of cancers. Therapeutic antibodies that bind EGFR are being evaluated in clinical trials as imaging agents for positro
Externí odkaz:
https://doaj.org/article/9a3e8851466844399ff266a99175fcea
Autor:
Md. Kausar Alam, Michelle Brabant, Raja Solomon Viswas, Kris Barreto, Humphrey Fonge, C. Ronald Geyer
Publikováno v:
BMC Biotechnology, Vol 18, Iss 1, Pp 1-8 (2018)
Abstract Background Advances in antibody engineering provide strategies to construct recombinant antibody-like molecules with modified pharmacokinetic properties. Multermerization is one strategy that has been used to produce antibody-like molecules
Externí odkaz:
https://doaj.org/article/26a22009f4c34a498dfba0e5984274b3
Autor:
Pargol Hashemi, Kris Barreto, Wendy Bernhard, Adam Lomness, Nicolette Honson, Tom A Pfeifer, P Richard Harrigan, Ivan Sadowski
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 2, Pp 160-174 (2017)
Abstract Highly active antiretroviral therapy (HAART) has improved the outlook for the HIV epidemic, but does not provide a cure. The proposed “shock‐and‐kill” strategy is directed at inducing latent HIV reservoirs, which may then be purged v
Externí odkaz:
https://doaj.org/article/01a3cd56f2dc4223af7260be31d0a938
Publikováno v:
Cancers
Cancers, Vol 14, Iss 300, p 300 (2022)
Cancers; Volume 14; Issue 2; Pages: 300
Cancers, Vol 14, Iss 300, p 300 (2022)
Cancers; Volume 14; Issue 2; Pages: 300
Simple Summary The immune system responds to abnormal cell growth by sending immune cells to kill them. The immune cell response is very important since it can usually stop abnormal cells from growing and spreading. Immuno-therapeutics used to treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef1988fde5ec0f71930edf6f4e88e4fb
http://europepmc.org/articles/PMC8773629
http://europepmc.org/articles/PMC8773629
Publikováno v:
Therapeutic Antibodies ISBN: 9781071614495
Phage display is commonly used to select target-binding antibody fragments from large libraries containing billions of unique antibody clones. In practice, selection outputs are often highly heterogenous, making it desirable to recover sequence infor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e731200b4c62de0bb3a1d7889a2b91c
https://doi.org/10.1007/978-1-0716-1450-1_6
https://doi.org/10.1007/978-1-0716-1450-1_6
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2313
Phage display is commonly used to select target-binding antibody fragments from large libraries containing billions of unique antibody clones. In practice, selection outputs are often highly heterogenous, making it desirable to recover sequence infor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0761fc7b5548d591fbe3278688b28d33
https://pubmed.ncbi.nlm.nih.gov/34478134
https://pubmed.ncbi.nlm.nih.gov/34478134
Autor:
Clarence Ronald Geyer, Viswas Raja Solomon, Kris Barreto, Humphrey Fonge, Rufael Chekol, Wayne Hill, Wendy Bernhard, Siddesh V. Hartimath, Elahe Alizadeh
Publikováno v:
Molecular Pharmaceutics. 16:4807-4816
Insulin growth factor receptor (IGF-1R) is overexpressed in many cancers of epithelial origin, where it confers enhanced proliferation and resistance to therapies targeted at other receptors. Anti-IGF-1R monoclonal antibodies have not demonstrated si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f92de3d118f7002697740aed4b7911d9
https://doi.org/10.1021/acs.molpharmaceut.9b00542
https://doi.org/10.1021/acs.molpharmaceut.9b00542