Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Krikor Dikranian"'
Autor:
George N. Chaldakov, Luigi Aloe, Stanislav G. Yanev, Marco Fiore, Anton B. Tonchev, Manlio Vinciguerra, Nikolai T. Evtimov, Peter Ghenev, Krikor Dikranian
Publikováno v:
Pharmaceuticals, Vol 17, Iss 7, p 961 (2024)
Many routes may lead to the transition from a healthy to a diseased phenotype. However, there are not so many routes to travel in the opposite direction; that is, therapy for different diseases. The following pressing question thus remains: what are
Externí odkaz:
https://doaj.org/article/e528d37e1f31482dafc8ff3f416bb83d
Autor:
Sarah E. Smith, Xiaoying Chen, Lindsey M. Brier, Jonathan R. Bumstead, Nicholas R. Rensing, Alison E. Ringel, Haewon Shin, Anna Oldenborg, Jan R. Crowley, Annie R. Bice, Krikor Dikranian, Joseph E. Ippolito, Marcia C. Haigis, Thomas Papouin, Guoyan Zhao, Michael Wong, Joseph P. Culver, Azad Bonni
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Mutations of α2-Na/K ATPase can cause familial hemiplegic migraine via unclear mechanisms. Here, the authors show that deletion of α2-Na/K ATPase in astrocytes results in gene expression and metabolic changes leading to cortical spreading depressio
Externí odkaz:
https://doaj.org/article/74f61a96ce2a40c79d4e03f28f0e919d
Autor:
Chainllie Young, Kevin A. Roth, Barbara J. Klocke, Tim West, David M. Holtzman, Joann Labruyere, Yue-Qin Qin, Krikor Dikranian, John W. Olney
Publikováno v:
Neurobiology of Disease, Vol 20, Iss 2, Pp 608-614 (2005)
Acute, transient exposure to ethanol causes a widespread pattern of caspase-3 activation and neuroapoptosis in the developing rodent brain. To determine whether caspase-3 activation is an essential step in ethanol-induced developmental neuroapoptosis
Externí odkaz:
https://doaj.org/article/ddbf78aae8964682938b87f19d085287
Autor:
John W. Olney, Tatyana Tenkova, Krikor Dikranian, Louis J. Muglia, Walter J. Jermakowicz, Cleta D'Sa, Kevin A. Roth
Publikováno v:
Neurobiology of Disease, Vol 9, Iss 2, Pp 205-219 (2002)
Recently several methods have been described for triggering extensive apoptotic neurodegeneration in the developing in vivo mammalian brain. These methods include treatment with drugs that block NMDA glutamate receptors, drugs that promote GABAA neur
Externí odkaz:
https://doaj.org/article/d8b4c8078c3c4af2818a4f5c9b66c340
Autor:
Krikor Dikranian, Masahiko J. Ishimaru, Tatyana Tenkova, Joann Labruyere, Y.Q. Qin, Chrysanthy Ikonomidou, John W. Olney
Publikováno v:
Neurobiology of Disease, Vol 8, Iss 3, Pp 359-379 (2001)
Apoptosis is a word originally introduced by Kerr, Wyllie, and colleagues for a cell death process they defined in terms of its ultrastructural appearance in nonneuronal cells from various tissues. There are very few studies providing detailed ultras
Externí odkaz:
https://doaj.org/article/00514373bd4744f38c0a5af8602fe518
Autor:
Kayla M. Kapral, Sasha L. Williams, Amber Li, Brant S. Swiney, Katherine Lucas, Krikor Dikranian, Jacob Huffman, Sophie H. Wang, Kevin K. Noguchi
Publikováno v:
J Neurosci
Zika virus (ZIKV) infection during pregnancy has been causally linked to a constellation of neurodevelopmental deformities in the fetus resulting in a disease termed congenital Zika syndrome (CZS). Here we detail how ZIKV infection produces extensive
nNOS regulates ciliated cell polarity, ciliary beat frequency, and directional flow in mouse trachea
Autor:
Tatyana V. Michurina, Natalia Peunova, Ken-Ichi Takemaru, Stephen Hearn, Anatoly Mikhailik, Krikor Dikranian, Vladimir I Maxakov, Grigori Enikolopov, Saul S. Siller
Publikováno v:
Life Science Alliance
Directional flow of mucus across the mucociliary epithelium enables the clearance of the airway. This study shows that nNOS supports the flow by regulating the planar polarity and ciliary beat frequency of ciliated cells in the tracheal epithelium.
Autor:
Jan R. Crowley, Azad Bonni, Joseph P. Culver, Thomas Papouin, Nicholas Rensing, Lindsey M. Brier, Annie R. Bice, Marcia C. Haigis, Joseph E. Ippolito, Anna Oldenborg, Krikor Dikranian, Michael Wong, Alison E. Ringel, Guoyan Zhao, Sarah E. Smith, Jonathan R. Bumstead, Xiaoying Chen, Haewon Shin
Publikováno v:
Communications Biology
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Familial hemiplegic migraine is an episodic neurological disorder characterized by transient sensory and motor symptoms and signs. Mutations of the ion pump α2-Na/K ATPase cause familial hemiplegic migraine, but the mechanisms by which α2-Na/K ATPa
Autor:
Tayler D. Sheahan, Steve Davidson, Bryan A. Copits, Robert W. Gereau, Krikor Dikranian, Jordan G. McCall, Melanie Y. Pullen, Manouela V. Valtcheva
Publikováno v:
Nature Protocols. 11:1877-1888
Primary cultures of rodent sensory neurons are widely used to investigate the cellular and molecular mechanisms involved in pain, itch, nerve injury, and regeneration. However, translation of these preclinical findings may be greatly improved by dire
Autor:
Krikor Dikranian, Saâd Jbabdi, Stamatios N. Sotiropoulos, Matteo Bastiani, Timothy E.J. Behrens, Michiel Cottaar, Charles D. Chen, David C. Van Essen
When axonal fibres approach or leave the cortex, their trajectories tend to closely follow the cortical convolutions. To quantify this tendency, we propose a three-dimensional coordinate system based on the gyral geometry. For every voxel in the brai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4eb5c749f5e46bb39d44a89ba9f1ca2
https://nottingham-repository.worktribe.com/file/948672/1/1-s2.0-S1053811918303501-main.pdf
https://nottingham-repository.worktribe.com/file/948672/1/1-s2.0-S1053811918303501-main.pdf