Genetic loci associated with heart rate variability and their effects on cardiac disease risk

Autor: Nolte, IM, Munoz, ML, Tragante, V, Amare, AT, Jansen, R, Vaez, A, Von Der Heyde, B, Avery, CL, Bis, JC, Dierckx, B, Van Dongen, J, Gogarten, SM, Goyette, P, Hernesniemi, J, Huikari, V, Hwang, SJ, Jaju, D, Kerr, KF, Kluttig, A, Krijthe, BP, Kumar, J, Van Der Laan, SW, Lyytikäinen, LP, Maihofer, AX, Minassian, A, Van Der Most, PJ, Müller-Nurasyid, M, Nivard, M, Salvi, E, Stewart, JD, Thayer, JF, Verweij, N, Wong, A, Zabaneh, D, Zafarmand, MH, Abdellaoui, A, Albarwani, S, Albert, C, Alonso, A, Ashar, F, Auvinen, J, Axelsson, T, Baker, DG, De Bakker, PIW, Barcella, M, Bayoumi, R, Bieringa, RJ, Boomsma, D, Boucher, G, Britton, AR, Christophersen, IE, Dietrich, A, Ehret, GB, Ellinor, PT, Eskola, M, Felix, JF, Floras, JS, Franco, OH, Friberg, P, Gademan, MGJ, Geyer, MA, Giedraitis, V, Hartman, CA, Hemerich, D, Hofman, A, Hottenga, JJ, Huikuri, H, Hutri-Kähönen, N, Jouven, X

Publikováno v: Nolte, IM; Munoz, ML; Tragante, V; Amare, AT; Jansen, R; Vaez, A; et al.(2017). Genetic loci associated with heart rate variability and their effects on cardiac disease risk. Nature Communications, 8. doi: 10.1038/ncomms15805. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/0xj2x119

Reduced cardiac vagal control reflected in low heart rate variability (HRV) is associated with greater risks for cardiac morbidity and mortality. In two-stage meta-analyses of genome-wide association studies for three HRV traits in up to 53,174 indiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::250e7329e3ec99c327dd406f35336a0f
http://www.escholarship.org/uc/item/0xj2x119

Paternal inflammatory arthritis is associated with a higher risk of miscarriage: results of a large multicentre study (iFAME-Fertility).

Autor: Perez-Garcia LF; Department of Rheumatology, Erasmus MC, University Medical Center, Rotterdam., Röder E; Department of Rheumatology, Erasmus MC, University Medical Center, Rotterdam., Smeele HTW; Department of Rheumatology, Erasmus MC, University Medical Center, Rotterdam., Goekoop R; Department of Rheumatology, Haga Hospital, The Hague., Hazes JMW; Department of Rheumatology, Erasmus MC, University Medical Center, Rotterdam., Kok MR; Department of Rheumatology and Clinical Immunology, Maasstad Hospital, Rotterdam., Tchetverikov I; Department of Rheumatology, Albert Schweitzer Hospital, Dordrecht., van der Helm-van Mil A; Department of Rheumatology, Erasmus MC, University Medical Center, Rotterdam.; Department of Rheumatology, Leiden University Medical Center, Leiden., van der Kaap J; Department of Rheumatology, Erasmus MC, University Medical Center, Rotterdam.; Department of Rheumatology, Admiraal de Ruyter Hospital, Goes., Kok P; Department of Rheumatology, Reinier de Graaf Hospital, Delft., Krijthe BP; Department of Rheumatology, Erasmus MC, University Medical Center, Rotterdam.; Department of Rheumatology, Sint Franciscus Vlietland Group, Rotterdam, Netherlands., Dolhain RJEM; Department of Rheumatology, Erasmus MC, University Medical Center, Rotterdam.

Publikováno v: Rheumatology (Oxford, England) [Rheumatology (Oxford)] 2022 Aug 03; Vol. 61 (8), pp. 3390-3395.

Pneumocystis pneumonia in patients with giant cell arteritis treated with high dose steroids: is there an indication for prophylaxis?

Autor: Krijthe BP; Department of Rheumatology, Franciscus Hospital, Rotterdam, the Netherlands. b.krijthe@franciscus.nl., Hogendoorn-van Zwienen EG; Department of Rheumatology, Franciscus Hospital, Rotterdam, the Netherlands., van Zeben D; Department of Rheumatology, Franciscus Hospital, Rotterdam, the Netherlands.

Publikováno v: Clinical and experimental rheumatology [Clin Exp Rheumatol] 2021 Mar-Apr; Vol. 39 Suppl 129 (2), pp. 189. Date of Electronic Publication: 2020 Nov 18.

PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity.

Autor: van Setten J; Department of Cardiology, University Medical Center Utrecht, University of Utrecht, Utrecht, 3584CX, The Netherlands. J.vanSetten@umcutrecht.nl., Brody JA; Department of Medicine, Cardiovascular Health Research Unit, University of Washington, Seattle, 98195, WA, USA., Jamshidi Y; Cardiogenetics Lab, Molecular and Clinical Sciences Research Institute, St George's University of London, London, SW17 0RE, UK., Swenson BR; Department of Medicine, Cardiovascular Health Research Unit, University of Washington, Seattle, 98195, WA, USA.; Institute for Public Health Genetics, School of Public Health, University of Washington, Seattle, 98195, WA, USA., Butler AM; Division of Infectious Diseases, Washington University School of Medicine, St. Louis, 63110, MO, USA., Campbell H; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, EH8 9YL, UK., Del Greco FM; Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, Bolzano, 39100, Italy., Evans DS; California Pacific Medical Center Research Institute, San Francisco, 94107, CA, USA., Gibson Q; Department of Surgery, University of Alabama Birmingham Hospital, Birmingham, 35233, AL, USA., Gudbjartsson DF; deCODE genetics/Amgen, Inc., Reykjavik, IS-101, Iceland.; School of Engineering and Natural Sciences, University of Iceland, Reykjavik, 101, Iceland., Kerr KF; Department of Biostatistics, School of Public Health, University of Washington, Seattle, 98195, WA, USA., Krijthe BP; Department of Epidemiology, Erasmus Medical Center, Rotterdam, 3015GD, The Netherlands., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, 33520, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, 33014, Finland., Müller C; Department of General and Interventional Cardiology, University Heart Center Hamburg-Eppendorf, Hamburg, 20251, Germany.; DZHK (German Center for Cardiovascular Research) Partner Site, Hamburg/Kiel/Lübeck, Germany., Müller-Nurasyid M; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, D-85764, Germany.; Department of Internal Medicine I (Cardiology), Hospital of the Ludwig-Maximilians-University (LMU) Munich, Munich, 81377, Germany.; DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, 80802, Germany.; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, 9713GZ, The Netherlands., Nolte IM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, 9713GZ, The Netherlands., Padmanabhan S; Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8TA, Scotland, UK., Ritchie MD; Department of Genetics, University of Pennsylvania, Philadelphia, PA 19104, PA, USA., Robino A; Institute for Maternal and Child Health-IRCCS 'Burlo Garofolo', Trieste, 34137, Italy., Smith AV; Icelandic Heart Association, Kopavogur, IS-201, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, 101, Iceland.; Department of Biostatistics, University of Michigan, Ann Arbor, 48109, MI, USA., Steri M; Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche (CNR), Monserrato, 00185, Cagliari, Italy., Tanaka T; Translational Gerontology Branch, NIA, Baltimore, 20892, MD, USA., Teumer A; Institute for Community Medicine, University Medicine Greifswald, Greifswald, 17489, Germany.; DZHK (German Centre for Cardiovascular Research), Partner Site Greifswald, 17475, Greifswald, Germany., Trompet S; Department of Cardiology, Leiden University Medical Center, Leiden, 2300RC, The Netherlands.; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, 2300RC, The Netherlands., Ulivi S; Institute for Maternal and Child Health-IRCCS 'Burlo Garofolo', Trieste, 34137, Italy., Verweij N; Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, 7913GZ, The Netherlands., Yin X; Department of Medicine, Boston University School of Medicine, Boston, 02118, MA, USA., Arnar DO; deCODE genetics/Amgen, Inc., Reykjavik, IS-101, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, 101, Iceland.; Department of Medicine, Landspitali University Hospital, Reykjavik, 101, Iceland., Asselbergs FW; Department of Cardiology, University Medical Center Utrecht, University of Utrecht, Utrecht, 3584CX, The Netherlands.; Durrer Center for Cardiogenetic Research, Netherlands Heart Institute, Utrecht, The Netherlands.; Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, WC1E 6BT, UK.; Farr Institute of Health Informatics Research and Institute of Health Informatics, University College London, London, WC1E 6BT, London, United Kingdom., Bader JS; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, 21218, MD, USA., Barnard J; Department of Quantitative Health Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, 44195, OH, USA., Bis J; Department of General and Interventional Cardiology, University Heart Center Hamburg-Eppendorf, Hamburg, 20251, Germany.; DZHK (German Center for Cardiovascular Research) Partner Site, Hamburg/Kiel/Lübeck, Germany., Blankenberg S; DZHK (German Center for Cardiovascular Research) Partner Site, Hamburg/Kiel/Lübeck, Germany.; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, D-85764, Germany., Boerwinkle E; Human Genetics Center, University of Texas Health Science Center at Houston, Houston, 77030, TX, USA., Bradford Y; Department of Genetics, University of Pennsylvania, Philadelphia, PA 19104, PA, USA., Buckley BM; Department of Pharmacology and Therapeutics, University College Cork, Cork, T12 K8AF, Ireland., Chung MK; Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, Cleveland, 44195, OH, USA.; Department of Molecular Cardiology, Lerner Research Institute, Cleveland Clinic, Cleveland, 44195, OH, USA., Crawford D; Institute for Computational Biology, Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, 44106, OH, USA., den Hoed M; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, SE-751 05, Sweden.; Science for Life Laboratory, Uppsala University, Uppsala, SE-751 05, Sweden., Denny JC; Biomedical Informatics and Medicine, Vanderbilt University, Nashville, 37235, TN, USA., Dominiczak AF; Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8TA, Scotland, UK., Ehret GB; Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, 21287, MD, USA., Eijgelsheim M; Department of Epidemiology, Erasmus Medical Center, Rotterdam, 3015GD, The Netherlands.; Department of Nephrology, University Medical Center Groningen, Groningen, 7913GZ, The Netherlands., Ellinor PT; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, 02142, MA, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, 02114, MA, USA.; Cardiac Arrhythmia Service, Massachusetts General Hospital, Boston, 02114, MA, USA., Felix SB; DZHK (German Centre for Cardiovascular Research), Partner Site Greifswald, 17475, Greifswald, Germany.; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, 17489, Germany., Franco OH; Department of Epidemiology, Erasmus Medical Center, Rotterdam, 3015GD, The Netherlands., Franke L; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, 7913GZ, The Netherlands., Harris TB; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Intramural Research Program, National Institutes of Health, Bethesda, 20892, MD, USA., Holm H; deCODE genetics/Amgen, Inc., Reykjavik, IS-101, Iceland., Ilaria G; Department of Medical Sciences, University of Trieste, Trieste, 34127, Italy., Iorio A; Cardiovascular Department, 'Ospedali Riuniti and University of Trieste', Trieste, 34124, Italy., Kähönen M; Department of Clinical Physiology, Tampere University Hospital, Tampere, 33521, Finland.; Department of Clinical Physiology, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, 33014, Finland., Kolcic I; Faculty of Medicine, University of Split, Split, 21000, Croatia., Kors JA; Department of Medical Informatics, Erasmus University Medical Center, Rotterdam, 3015GD, The Netherlands., Lakatta EG; Laboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, Baltimore, 20892, MD, USA., Launer LJ; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Intramural Research Program, National Institutes of Health, Bethesda, 20892, MD, USA., Lin H; Department of Medicine, Boston University School of Medicine, Boston, 02118, MA, USA., Lin HJ; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, 90502, CA, USA., Loos RJF; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, 10029, NY, USA.; The Mindich Child health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, 10029, NY, USA., Lubitz SA; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, 02142, MA, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, 02114, MA, USA.; Cardiac Arrhythmia Service, Massachusetts General Hospital, Boston, 02114, MA, USA., Macfarlane PW; Institute of Health and Wellbeing, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8QQ, UK., Magnani JW; Department of Medicine, Division of Cardiology, University of Pittsburgh Medical Center Heart and Vascular Institute, University of Pittsburgh, Pittsburgh, 15260, PA, USA., Leach IM; Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, 7913GZ, The Netherlands., Meitinger T; DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, 80802, Germany.; Institute of Human Genetics, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, 85764, Germany.; Institute of Human Genetics, Klinikum rechts der Isar, Technische Universität München, Munich, 81675, Germany., Mitchell BD; Department of Medicine, University of Maryland School of Medicine, Geriatrics Research and Education Clinical Center, Baltimore VA Medical Center, Baltimore, 21201, MD, USA., Munzel T; Center for Cardiology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, 55131, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Rhine-Main, Mainz, 55131, Germany.; Center for Translational Vascular Biology (CTVB), University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, 55131, Germany., Papanicolaou GJ; Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, NIH, Bethesda, 20892, MD, USA., Peters A; DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, 80802, Germany.; Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, 85764, Germany.; German Center for Diabetes Research, Neuherberg, 85764, Germany., Pfeufer A; MVZ für Molekulardiagnostik, Munich, 81543, Germany., Pramstaller PP; Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, Bolzano, 39100, Italy.; Department of Neurology, Central Hospital, Bolzano, 39100, Italy., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, 20521, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, 20014, Finland., Rotter JI; Departments of Medicine and Pediatrics, The Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, 90502, CA, USA., Rudan I; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, EH8 9YL, UK., Samani NJ; Department of Cardiovascular Sciences, University of Leicester, Leicester, LE1 7RH, UK.; NIHR Leicester Biomedical Research Centre, Leicester, LE3 9QD, UK., Schlessinger D; Laboratory of Genetics and Genomics, National Institute on Aging, National Institute of Health, Baltimore, 20892, MD, USA., Silva Aldana CT; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015GD, The Netherlands.; Institute of Translational Medicine-IMT, Center For Research in Genetics and Genomics-CIGGUR, GENIUROS Research Group, School of Medicine and Health Sciences, Universidad del Rosario, Bogotá, Cl. 12c #6-25, Colombia., Sinner MF; Department of Internal Medicine I (Cardiology), Hospital of the Ludwig-Maximilians-University (LMU) Munich, Munich, 81377, Germany.; DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, 80802, Germany., Smith JD; Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, Cleveland, 44195, OH, USA.; Department of Cellular and Molecular Medicine Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, 44195, OH, USA., Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, 9713GZ, The Netherlands., Soliman EZ; Epidemiological Cardiology Research Center, Wake Forest School of Medicine, Winston-Salem, 27101, NC, USA., Spector TD; Department of Twin Research and Genetic Epidemiology, St Thomas Hospital, King's College London, London, WC2R 2LS, UK., Stott DJ; Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8TA, Scotland, UK., Strauch K; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, D-85764, Germany.; Chair of Genetic Epidemiology, IBE, Faculty of Medicine, LMU Munich, Munich, 81377, Germany., Tarasov KV; Laboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, Baltimore, 20892, MD, USA., Thorsteinsdottir U; deCODE genetics/Amgen, Inc., Reykjavik, IS-101, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, 101, Iceland., Uitterlinden AG; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, 3015GD, The Netherlands., Van Wagoner DR; Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, Cleveland, 44195, OH, USA.; Department of Molecular Cardiology, Lerner Research Institute, Cleveland Clinic, Cleveland, 44195, OH, USA., Völker U; DZHK (German Centre for Cardiovascular Research), Partner Site Greifswald, 17475, Greifswald, Germany.; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, 17489, Germany., Völzke H; Institute for Community Medicine, University Medicine Greifswald, Greifswald, 17489, Germany.; DZHK (German Centre for Cardiovascular Research), Partner Site Greifswald, 17475, Greifswald, Germany., Waldenberger M; DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, 80802, Germany.; Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, 85764, Germany.; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, 85764, Germany., Jan Westra H; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, 7913GZ, The Netherlands., Wild PS; DZHK (German Center for Cardiovascular Research), Partner Site Rhine-Main, Mainz, 55131, Germany.; Center for Translational Vascular Biology (CTVB), University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, 55131, Germany.; Preventive Cardiology and Preventive Medicine, Center for Cardiology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, 55131, Germany.; Center for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, 55131, Germany., Zeller T; Department of General and Interventional Cardiology, University Heart Center Hamburg-Eppendorf, Hamburg, 20251, Germany.; DZHK (German Center for Cardiovascular Research) Partner Site, Hamburg/Kiel/Lübeck, Germany., Alonso A; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, 30322, GA, USA., Avery CL; Department of Epidemiology and Carolina Population Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27514, USA., Bandinelli S; Geriatric Unit, Azienda Sanitaria Firenze (ASF), Florence, 50122, Italy., Benjamin EJ; Durrer Center for Cardiogenetic Research, Netherlands Heart Institute, Utrecht, The Netherlands., Cucca F; Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche (CNR), Monserrato, 00185, Cagliari, Italy., Dörr M; DZHK (German Centre for Cardiovascular Research), Partner Site Greifswald, 17475, Greifswald, Germany.; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, 17489, Germany., Ferrucci L; Translational Gerontology Branch, NIA, Baltimore, 20892, MD, USA., Gasparini P; Institute for Maternal and Child Health-IRCCS 'Burlo Garofolo', Trieste, 34137, Italy.; Department of Medical Sciences, University of Trieste, Trieste, 34127, Italy., Gudnason V; Icelandic Heart Association, Kopavogur, IS-201, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, 101, Iceland., Hayward C; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH8 9YL, UK., Heckbert SR; Cardiovascular Health Research Unit and the Department of Epidemiology, University of Washington, Seattle, 98195, WA, USA., Hicks AA; Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, Bolzano, 39100, Italy., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden, 2300RC, The Netherlands.; Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, 2300RC, The Netherlands.; Interuniversity Cardiology Institute of the Netherlands, Utrecht, 3511EP, The Netherlands., Kääb S; Department of Internal Medicine I (Cardiology), Hospital of the Ludwig-Maximilians-University (LMU) Munich, Munich, 81377, Germany.; DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, 80802, Germany., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, 33520, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, 33014, Finland., Liu Y; Department of Epidemiology and Prevention, Division of Public Health Sciences, Wake Forest University, Winston-Salem, 27101, NC, USA., Munroe PB; Clinical Pharmacology, William Harvey Research Institute, Queen Mary University of London, London, E1 4NS, UK.; NIHR Biomedical Research Centre at Barts, Barts Health NHS Trust and Queen Mary University of London, London, E1 4NS, UK., Parsa A; Department of Medicine, University of Maryland School of Medicine and Baltimore VA Medical Center, Baltimore, 21201, MD, USA., Polasek O; Faculty of Medicine, University of Split, Split, 21000, Croatia.; Psychiatric hospital 'Sveti Ivan', Zagreb, 10000, Croatia.; Gen-info Ltd., Zagreb, 10000, Croatia., Psaty BM; Cardiovascular Health Research Unit, Departments of Medicine, Epidemiology and Health Services, University of Washington, Seattle, 98195, WA, USA.; Kaiser Permanente Washington Health Research Institute, Seattle, 98101, WA, USA., Roden DM; Medicine, Pharmacology, and Biomedical Informatics, Vanderbilt University, Nashville, 37235, TN, USA., Schnabel RB; Department of General and Interventional Cardiology, University Heart Center Hamburg-Eppendorf, Hamburg, 20251, Germany.; DZHK (German Center for Cardiovascular Research) Partner Site, Hamburg/Kiel/Lübeck, Germany., Sinagra G; Cardiovascular Department, 'Ospedali Riuniti and University of Trieste', Trieste, 34124, Italy., Stefansson K; deCODE genetics/Amgen, Inc., Reykjavik, IS-101, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, 101, Iceland., Stricker BH; Department of Epidemiology, Erasmus Medical Center, Rotterdam, 3015GD, The Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, 3015GD, The Netherlands.; Inspectorate for Health Care, The Hague, 2511VX, The Netherlands., van der Harst P; Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, 7913GZ, The Netherlands.; University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, 7913GZ, The Netherlands.; Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, Utrecht, 3511EP, The Netherlands., van Duijn CM; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015GD, The Netherlands., Wilson JF; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, EH8 9YL, UK.; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH8 9YL, UK., Gharib SA; Cardiovascular Health Research Unit, Division of Pulmonary Critical Care and Sleep Medicine, Computational Medicine Core at Center for Lung Biology, Department of Medicine, University of Washington, Seattle, 98195, WA, USA., de Bakker PIW; Department of Genetics, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, 3584CX, The Netherlands.; Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, 3584CX, The Netherlands., Isaacs A; CARIM School for Cardiovascular Diseases, Maastricht, 6229ER, The Netherlands.; Center for Systems Biology (MaCSBio), Maastricht University, Maastricht, 6229ER, The Netherlands.; Department of Biochemistry, Maastricht University, Maastricht, 6229ER, The Netherlands., Arking DE; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, 21287, MD, USA., Sotoodehnia N; Departments of Medicine and Epidemiology, Cardiovascular Health Research Unit, Division of Cardiology, University of Washington, Seattle, 98101, WA, USA. nsotoo@u.washington.edu.

Publikováno v: Nature communications [Nat Commun] 2018 Jul 25; Vol. 9 (1), pp. 2904. Date of Electronic Publication: 2018 Jul 25.

Genetic Interactions with Age, Sex, Body Mass Index, and Hypertension in Relation to Atrial Fibrillation: The AFGen Consortium.

Autor: Weng LC; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Lunetta KL; National Heart Lung and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Müller-Nurasyid M; DZHK (German Centre for Cardiovascular Research), partner site: Munich Heart Alliance, Munich, Germany.; Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.; Department of Medicine I, University Hospital Munich, Ludwig-Maximilians-University, Munich, Germany., Smith AV; Icelandic Heart Association, 201, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, 101, Reykjavik, Iceland., Thériault S; Population Health Research Institute, Hamilton, Canada.; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Canada., Weeke PE; Department of Medicine, Vanderbilt University, Nashville, TN, USA.; Department of Cardiology, The Heart Centre, Rigshospitalet, Copenhagen, Denmark., Barnard J; Department of Quantitative Health Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA., Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories and Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Kleber ME; Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty of Mannheim, University of Heidelberg, Mannheim, Germany., Martinsson A; Department of Cardiology, Lund University and Skåne University Hospital, Lund, Sweden., Lin HJ; Institute for Translational Genomics and Population Sciences and Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California, USA.; Division of Medical Genetics, Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, California, USA., Rienstra M; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Trompet S; Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands., Krijthe BP; Department of Epidemiology, Erasmus Medical Center, University Medical Center, Rotterdam, The Netherlands., Dörr M; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany., Klarin D; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Human Genetic Research, Cardiovascular Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; Department of Surgery, Massachusetts General Hospital, Boston, MA, USA., Chasman DI; Divisions of Preventive Medicine and Genetics, Brigham and Women's Hospital, Boston, MA, USA., Sinner MF; DZHK (German Centre for Cardiovascular Research), partner site: Munich Heart Alliance, Munich, Germany.; Department of Medicine I, University Hospital Munich, Ludwig-Maximilians-University, Munich, Germany., Waldenberger M; DZHK (German Centre for Cardiovascular Research), partner site: Munich Heart Alliance, Munich, Germany.; Research unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany., Launer LJ; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Intramural Research Program, National Institutes of Health, Bethesda, Maryland, 20892, USA., Harris TB; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Intramural Research Program, National Institutes of Health, Bethesda, Maryland, 20892, USA., Soliman EZ; 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Publikováno v: Scientific reports [Sci Rep] 2017 Sep 12; Vol. 7 (1), pp. 11303. Date of Electronic Publication: 2017 Sep 12.