Zobrazeno 1 - 10
of 751
pro vyhledávání: '"Krenek P."'
Autor:
Veteskova J., Obsivan M., Kmecova Z., Radik M., Srankova J., Malikova E., Klimas J., Krenek P.
Publikováno v:
European Pharmaceutical Journal, Vol 65, Iss 2, Pp 23-26 (2018)
Aim: Chemokine stromal cell derived factor-1 (SDF-1) plays an important role in many processes such as apoptosis, proliferation, migration and angiogenesis, and these effects are mediated mostly by the receptor CXCR4. The aim of this study was to det
Externí odkaz:
https://doaj.org/article/6ff4cb542398422b8c4dc1b8ed5aaca4
Autor:
Kmecova Z., Malikova E., Zsigmondova B., Radik M., Veteskova J., Marusakova M., Krenek P., Klimas J.
Publikováno v:
European Pharmaceutical Journal, Vol 65, Iss 2, Pp 4-7 (2018)
Aim: Nitric oxide signalling pathway showed to be one of the crucial factors in the treatment and pathogenesis of pulmonary arterial hypertension. The aim of this study was to determine the effect of administration of inorganic nitrate, NaNO3, on the
Externí odkaz:
https://doaj.org/article/f71100da87fe43a895b7893235fe7b86
Publikováno v:
European Pharmaceutical Journal, Vol 64, Iss 1, Pp 22-25 (2017)
Blood pressure (BP) rhythm is exhibited in a circadian pattern regulated by complex system of endogenous factors. Administration of pharmacological treatment at the right time can influence the efficacy of treatment; but while kidneys play significan
Externí odkaz:
https://doaj.org/article/8754a12b27fc435ba6f888b8e85d5984
Publikováno v:
European Pharmaceutical Journal, Vol 63, Iss 1, Pp 12-15 (2016)
Aim: The aim of this study is to identify a possible damage to heart ventricles caused by supraphysiological doses of testosterone, voluntary physical activity or their combination.
Externí odkaz:
https://doaj.org/article/e74efb3ab1f44711906d39897a97337d
Autor:
Palermo, Gianluca, Accordi, Gianmarco, Gadioli, Davide, Vitali, Emanuele, Silvano, Cristina, Guindani, Bruno, Ardagna, Danilo, Beccari, Andrea R., Bonanni, Domenico, Talarico, Carmine, Lunghini, Filippo, Martinovic, Jan, Silva, Paulo, Bohm, Ada, Beranek, Jakub, Krenek, Jan, Jansik, Branislav, Crisci, Luigi, Biagio, Cosenza, Thoman, Peter, Salzmann, Philip, Fahringer, Thomas, Alexander, Leila, Tauriello, Gerardo, Schwede, Torsten, Durairaj, Janani, Emerson, Andrew, Ficarelli, Federico, Wingbermuhle, Sebastian, Lindahl, Eric, Gregori, Daniele, Sana, Emanuele, Coletti, Silvano, Gschwandtner, Philip
Today digital revolution is having a dramatic impact on the pharmaceutical industry and the entire healthcare system. The implementation of machine learning, extreme-scale computer simulations, and big data analytics in the drug design and developmen
Externí odkaz:
http://arxiv.org/abs/2304.09953
Identification of experimentally acquired mass spectra of unknown compounds presents a~particular challenge because reliable spectral databases do not cover the potential chemical space with sufficient density. Therefore machine learning based \emph{
Externí odkaz:
http://arxiv.org/abs/2304.01634
Autor:
Calatrava, Amanda, Asorey, Hernán, Astalos, Jan, Azevedo, Alberto, Benincasa, Francesco, Blanquer, Ignacio, Bobak, Martin, Brasileiro, Francisco, Codó, Laia, del Cano, Laura, Esteban, Borja, Ferret, Meritxell, Handl, Josef, Kerzenmacher, Tobias, Kozlov, Valentin, Křenek, Aleš, Martins, Ricardo, Pavesio, Manuel, Rubio-Montero, Antonio Juan, Sánchez-Ferrero, Juan
Open Science is a paradigm in which scientific data, procedures, tools and results are shared transparently and reused by society as a whole. The initiative known as the European Open Science Cloud (EOSC) is an effort in Europe to provide an open, tr
Externí odkaz:
http://arxiv.org/abs/2211.07738
Autor:
Andrea M. Krenek, Anne Mathews, Juen Guo, Amber B. Courville, Carl J. Pepine, Stephanie T. Chung, Monica Aggarwal
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 15 (2024)
Background Whole‐food, plant‐based vegan diets, low in oils, and Mediterranean diets, rich in extra virgin olive oil (EVOO), reduce cardiovascular disease risk factors. Optimal quantity of dietary fat, particularly EVOO, is unclear. Methods and R
Externí odkaz:
https://doaj.org/article/4f68993a0d0842b58eaca8caa17276b4
Publikováno v:
Front. Mol. Biosci. 9, 878133 (2022)
AlphaFold is a neural-network-based tool for the prediction of 3D structures of protein. In CASP14, a blind structure prediction challenge, it performed significantly better than other competitors, which makes it the best available structure predicti
Externí odkaz:
http://arxiv.org/abs/2203.04848
Publikováno v:
EDIS, Vol 2024, Iss 1 (2024)
Diet and lifestyle behaviors can affect health status and the development of disease. The importance of nutrition in healthcare is especially relevant as one in five deaths globally can be connected to poor diet. Food can be an integral part of preve
Externí odkaz:
https://doaj.org/article/9442aede57644e698b2bfb77a3304b16