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Design, synthesis, and structure-activity relationships of diindolylmethane derivatives as cannabinoid CB 2 receptor agonists.

Autor: Mahardhika AB; Department of Pharmaceutical & Medicinal Chemistry, PharmaCenter Bonn, Pharmaceutical Institute, University of Bonn, Bonn, Germany.; Research Training Group 1873, University of Bonn, Bonn, Germany., Ressemann A; Department of Pharmaceutical & Medicinal Chemistry, PharmaCenter Bonn, Pharmaceutical Institute, University of Bonn, Bonn, Germany., Kremers SE; Department of Pharmaceutical & Medicinal Chemistry, PharmaCenter Bonn, Pharmaceutical Institute, University of Bonn, Bonn, Germany., Gregório Castanheira MS; Department of Pharmaceutical & Medicinal Chemistry, PharmaCenter Bonn, Pharmaceutical Institute, University of Bonn, Bonn, Germany., Schoeder CT; Department of Pharmaceutical & Medicinal Chemistry, PharmaCenter Bonn, Pharmaceutical Institute, University of Bonn, Bonn, Germany.; Research Training Group 1873, University of Bonn, Bonn, Germany., Müller CE; Department of Pharmaceutical & Medicinal Chemistry, PharmaCenter Bonn, Pharmaceutical Institute, University of Bonn, Bonn, Germany.; Research Training Group 1873, University of Bonn, Bonn, Germany., Pillaiyar T; Department of Pharmaceutical & Medicinal Chemistry, PharmaCenter Bonn, Pharmaceutical Institute, University of Bonn, Bonn, Germany.; Pharmaceutical/Medicinal Chemistry and Tübingen Center for Academic Drug Discovery, Institute of Pharmacy, Eberhard Karls University, Tübingen, Germany.

Publikováno v: Archiv der Pharmazie [Arch Pharm (Weinheim)] 2023 Mar; Vol. 356 (3), pp. e2200493. Date of Electronic Publication: 2022 Nov 27.