Characterization of cervical biopsies of women with HIV and HPV co-infection using p16ink4a, ki-67 and HPV E4 immunohistochemistry and DNA methylation

Autor: Kremer, Wieke W., Vink, Frederique J., van Zummeren, Marjolein, Dreyer, Greta, Rozendaal, Lawrence, Doorbar, John, Bleeker, Maaike C.G., Meijer, Chris J. L.M.

Publikováno v: In Modern Pathology October 2020 33(10):1968-1978

HPV E4 expression and DNA hypermethylation of CADM1, MAL, and miR124-2 genes in cervical cancer and precursor lesions

Autor: Zummeren, Marjolein van, Kremer, Wieke W., Leeman, Annemiek, Bleeker, Maaike C.G., Jenkins, David, Sandt, Miekel van de, Doorbar, John, Heideman, Daniëlle A.M., Steenbergen, Renske D.M., Snijders, Peter J.F., Kenter, Gemma G., Quint, Wim G.V., Berkhof, Johannes, Meijer, Chris J. L.M.

Publikováno v: In Modern Pathology December 2018 31(12):1842-1850

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Clinical Regression of High-Grade Cervical Intraepithelial Neoplasia Is Associated With Absence of DNA Methylation (CONCERVE Study).

Autor: Kremer, Wieke W., Dick, Stèfanie, Heideman, Daniëlle A.M., Steenbergen, Renske D.M., Bleeker, Maaike C.G., Verhoeve, Harold R., van Baal, W. Marchien, van Trommel, Nienke, Kenter, Gemma G., Meijer, Chris J.L.M., Berkhof, Johannes

Publikováno v: Journal of Clinical Oncology; 9/10/2022, Vol. 40 Issue 26, p3037-3046, 10p

Three-tiered score for Ki-67 and p16 improves accuracy and reproducibility of grading CIN lesions

Autor: van Zummeren, Marjolein, Leeman, Annemiek, Kremer, Wieke W, Bleeker, Maaike C G, Jenkins, David, van de Sandt, Miekel, Heideman, Daniëlle A M, Steenbergen, Renske, Snijders, Peter J F, Quint, Wim G V, Berkhof, Johannes, Meijer, Chris J L M

Publikováno v: van Zummeren, M, Leeman, A, Kremer, W W, Bleeker, M C G, Jenkins, D, van de Sandt, M, Heideman, D A M, Steenbergen, R, Snijders, P J F, Quint, W G V, Berkhof, J & Meijer, C J L M 2018, ' Three-tiered score for Ki-67 and p16 improves accuracy and reproducibility of grading CIN lesions ', Journal of Clinical Pathology, vol. 71, no. 11, pp. 981-988 . https://doi.org/10.1136/jclinpath-2018-205271
Journal of Clinical Pathology, 71(11), 981-988. BMJ Publishing Group

AIMS: To investigate the accuracy and reproducibility of a scoring system for cervical intraepithelial neoplasia (CIN1-3) based on immunohistochemical (IHC) biomarkers Ki-67 and p16ink4a.METHODS: 115 cervical tissue specimens were reviewed by three e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::8ef09b4e5262a26b395988f4fbace8d4
https://research.vumc.nl/en/publications/500631ab-dff2-41ef-8a98-27cb8d6f62d9