Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Krekels, Elke HJ"'
Autor:
van Rongen, Anne, Krekels, Elke HJ, Calvier, Elisa AM, de Wildt, Saskia N, Vermeulen, An, Knibbe, Catherijne AJ
When pediatric data are not available for a drug, allometric and other methods are applied to scale drug clearance across the pediatric age-range from adult values. This is applied when designing first-in-child studies, but also for off-label drug pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47362d99b809d92ebc32239999d89e47
Publikováno v:
Expert Opinion on Drug Metabolism & Toxicology; January 2011, Vol. 7 Issue: 1 p1-8, 8p
Autor:
Krekels, Elke HJ, Anker, John N van den, Baiardi, Paola, Cella, Massimo, Cheng, Katharine Y, Gibb, Diana M, Green, Hannah, Iolascon, Achille, Jacqz-Aigrain, Evelyne M, Knibbe, Catherijne AJ, Santen, Gijs WE, Schaik, Ron HN van, Tibboel, Dick, Pasqua, Oscar E Della
Publikováno v:
Expert Opinion on Pharmacotherapy; August 2007, Vol. 8 Issue: 12 p1787-1799, 13p
Autor:
van Rongen A; Division of Systems Biomedicine and Pharmacology, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands., Krekels EH; Division of Systems Biomedicine and Pharmacology, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands., Calvier EA; Sanofi Pharmacokinetics-Dynamics and Metabolism (PKDM), Translational Medicine and Early Development, Sanofi R&d, Montpellier, France., de Wildt SN; Department of Pharmacology and Toxicology, Radboud University Medical Center, Nijmegen, The Netherlands.; Intensive Care and Department of Pediatric Surgery, Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands., Vermeulen A; Laboratory of Medical Biochemistry and Clinical Analysis, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium.; Janssen R&D, a Division of Janssen Pharmaceutica Nv, Beerse, Belgium., Knibbe CA; Division of Systems Biomedicine and Pharmacology, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands.; Department of Clinical Pharmacy, St. Antonius Hospital, Nieuwegein, The Netherlands.
Publikováno v:
Expert opinion on drug metabolism & toxicology [Expert Opin Drug Metab Toxicol] 2022 Feb; Vol. 18 (2), pp. 99-113. Date of Electronic Publication: 2022 Feb 25.