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of 1 800
pro vyhledávání: '"Krawetz, A. A."'
Autor:
Breanna S. Borys, Tiffany Dang, Hannah Worden, Leila Larijani, Jessica M. Corpuz, Brett D. Abraham, Emilie J. Gysel, Julia Malinovska, Roman Krawetz, Tamas Revay, Bob Argiropoulos, Derrick E. Rancourt, Michael S. Kallos, Sunghoon Jung
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Background While pluripotent stem cell (PSC) therapies move toward clinical and commercial applications at a rapid rate, manufacturing reproducibility and robustness are notable bottlenecks in regulatory approval. Therapeutic applications of
Externí odkaz:
https://doaj.org/article/2db8d01dfcf348088a43dc9d70f85a86
Autor:
Matthew Hamilton, Stewart Russell, Grace M. Swanson, Stephen A. Krawetz, Karen Menezes, Sergey I. Moskovtsev, Clifford Librach
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Current approaches to diagnosing male infertility inadequately assess the complexity of the male gamete. Beyond the paternal haploid genome, spermatozoa also deliver coding and non-coding RNAs to the oocyte. While sperm-borne RNAs have demon
Externí odkaz:
https://doaj.org/article/fec812a155d84fc08d088ac99df539a2
Akademický článek
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Autor:
Roman J. Krawetz, Leila Larijani, Jessica May Corpuz, Nicoletta Ninkovic, Nabangshu Das, Alexandra Olsen, Nicholas Mohtadi, Alexander Rezansoff, Antoine Dufour
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Background Osteoarthritis (OA) is a chronic debilitating disease impacting a significant percentage of the global population. While there are numerous surgical and non-invasive interventions that can postpone joint replacement, there are no
Externí odkaz:
https://doaj.org/article/f0e94d7d37bb452a82633e24c25869b6
Exogenously delivered iPSCs disrupt the natural repair response of endogenous MPCs after bone injury
Autor:
Leah Ferrie, Priyatha Premnath, Alexandra Olsen, Leila Larijani, Bryce A. Besler, Derrick E. Rancourt, Neil A. Duncan, T. Michael Underhill, Roman J. Krawetz
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract Promoting bone healing including fracture non-unions are promising targets for bone tissue engineering due to the limited success of current clinical treatment methods. There has been significant research on the use of stem cells with and wi
Externí odkaz:
https://doaj.org/article/5e9c50e958ae434a8e717179d078fa47
Autor:
Nabangshu Das, Luiz G. N. de Almeida, Afshin Derakhshani, Daniel Young, Kobra Mehdinejadiani, Paul Salo, Alexander Rezansoff, Gregory D. Jay, Christian P. Sommerhoff, Tannin A. Schmidt, Roman Krawetz, Antoine Dufour
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Altered expression and function of the extracellular matrix protein PRG4 have been associated with osteoarthritis. Here, the authors show that mast cell tryptase β cleaves PRG4, resulting in a reduction of lubrication and activation of inflammation
Externí odkaz:
https://doaj.org/article/acd1e0dd071f4882af74316106133957
Autor:
Oluwayiose, Oladele A., Houle, Emily, Whitcomb, Brian W., Suvorov, Alexander, Rahil, Tayyab, Sites, Cynthia K., Krawetz, Stephen A., Visconti, Pablo E., Pilsner, J. Richard
Publikováno v:
In Environmental Pollution 15 July 2023 329
Publikováno v:
Epigenetics & Chromatin, Vol 16, Iss 1, Pp 1-21 (2023)
Abstract Background Preconception exposure to phthalates such as the anti-androgenic dibutyl-phthalate (DBP) impacts both male and female reproduction, yet how this occurs largely remains unknown. Previously we defined a series of RNAs expressly prov
Externí odkaz:
https://doaj.org/article/4a4ac23d03834adc84c7cae83624bec9
Akademický článek
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Autor:
Roman J. Krawetz, Asmaa Affan, Catherine Leonard, Dwaraka Natha Veeramreddy, Akash Fichadiya, Liam Martin, Heinrike Schmeling
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Juvenile idiopathic arthritis (JIA) is a heterogeneous group of inflammatory diseases affecting joints with a prevalence of one in a thousand children. There is a growing body of literature examining the use of mesenchymal stem/progenitor ce
Externí odkaz:
https://doaj.org/article/3748ff51de754ace9b7710b1cde2ba01