Novel long-term anticonvulsant treatment with gabapentin without causing memory impairment in mice

Autor: Blake MG, Boccia MM, Carcaboso AM, Chiappetta DA, Höcht C, Krawczyk MC, Sosnik A, Baratti CM

Publikováno v: EPILEPSY & BEHAVIOR
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
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r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu

We previously reported that administration of a single dose of gabapentin (GBP) immediately after training improves memory of mice in an inhibitory avoidance task (IA), whereas GBP administered repeatedly for 7 days impairs memory This is in accordan

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http://fundanet.fsjd.org/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=13025

The role of the claustrum in the acquisition, consolidation and reconsolidation of memories in mice.

Autor: Medina C; Facultad de Farmacia y Bioquímica (FFyB), Cátedra de Farmacología, Laboratorio de Neurofarmacología de los Procesos de Memoria, Universidad de Buenos Aires (UBA), Buenos Aires, Argentina.; Facultad de Ciencias Exactas y Naturales (FCEyN), Departamento de Fisiologia, Biologia Molecular y Celular (DFBMC), Universidad de Buenos Aires (UBA), Buenos Aires, Argentina.; Instituto de Fisiología, Biología Molecular y Neurociencias (IFIBYNE), Universidad de Buenos Aires (UBA)-CONICET, Buenos Aires, Argentina., Ojea Ramos S; Instituto de Fisiología, Biología Molecular y Neurociencias (IFIBYNE), Universidad de Buenos Aires (UBA)-CONICET, Buenos Aires, Argentina., Depino AM; Instituto de Fisiología, Biología Molecular y Neurociencias (IFIBYNE), Universidad de Buenos Aires (UBA)-CONICET, Buenos Aires, Argentina.; Facultad de Ciencias Exactas y Naturales (FCEyN), Departamento de Biodiversidad y Biología Experimental (DBBE), Universidad de Buenos Aires (UBA), Buenos Aires, Argentina., Romano AG; Facultad de Ciencias Exactas y Naturales (FCEyN), Departamento de Fisiologia, Biologia Molecular y Celular (DFBMC), Universidad de Buenos Aires (UBA), Buenos Aires, Argentina.; Instituto de Fisiología, Biología Molecular y Neurociencias (IFIBYNE), Universidad de Buenos Aires (UBA)-CONICET, Buenos Aires, Argentina., Krawczyk MC; Facultad de Farmacia y Bioquímica (FFyB), Cátedra de Farmacología, Laboratorio de Neurofarmacología de los Procesos de Memoria, Universidad de Buenos Aires (UBA), Buenos Aires, Argentina., Boccia MM; Facultad de Farmacia y Bioquímica (FFyB), Cátedra de Farmacología, Laboratorio de Neurofarmacología de los Procesos de Memoria, Universidad de Buenos Aires (UBA), Buenos Aires, Argentina. mboccia@ffyb.uba.ar.

Publikováno v: Scientific reports [Sci Rep] 2024 Oct 18; Vol. 14 (1), pp. 24409. Date of Electronic Publication: 2024 Oct 18.

Lymphocyte deficiency alters the transcriptomes of oligodendrocytes, but not astrocytes or microglia.

Autor: Krawczyk MC; Department of Psychiatry and Biobehavioral Sciences, Intellectual and Developmental Disabilities Research Center, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California Los Angeles (UCLA), Los Angeles, Los Angeles, California, United States of America., Pan L; Department of Psychiatry and Biobehavioral Sciences, Intellectual and Developmental Disabilities Research Center, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California Los Angeles (UCLA), Los Angeles, Los Angeles, California, United States of America., Zhang AJ; Department of Psychiatry and Biobehavioral Sciences, Intellectual and Developmental Disabilities Research Center, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California Los Angeles (UCLA), Los Angeles, Los Angeles, California, United States of America., Zhang Y; Department of Psychiatry and Biobehavioral Sciences, Intellectual and Developmental Disabilities Research Center, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California Los Angeles (UCLA), Los Angeles, Los Angeles, California, United States of America.; Brain Research Institute, University of California Los Angeles (UCLA), Los Angeles, Los Angeles, California, United States of America.; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California Los Angeles (UCLA), Los Angeles, Los Angeles, California, United States of America.; Molecular Biology Institute, University of California Los Angeles (UCLA), Los Angeles, Los Angeles, California, United States of America.

Publikováno v: PloS one [PLoS One] 2023 Feb 24; Vol. 18 (2), pp. e0279736. Date of Electronic Publication: 2023 Feb 24 (Print Publication: 2023).

Oxytocin-Cholinergic Central Interaction: Implications for Non-Social Memory Formation.

Autor: Medina C; Laboratorio de Neurofarmacología de los Procesos de Memoria, Cátedra de Farmacología, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires (UBA), Buenos Aires, Argentina., Krawczyk MC; Laboratorio de Neurofarmacología de los Procesos de Memoria, Cátedra de Farmacología, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires (UBA), Buenos Aires, Argentina., Millan J; Laboratorio de Neurofarmacología de los Procesos de Memoria, Cátedra de Farmacología, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires (UBA), Buenos Aires, Argentina., Blake MG; Instituto de Fisiología y Biofísica (IFIBIO UBA-CONICET), Facultad de Medicina, Universidad de Buenos Aires (UBA), Buenos Aires, Argentina., Boccia MM; Laboratorio de Neurofarmacología de los Procesos de Memoria, Cátedra de Farmacología, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires (UBA), Buenos Aires, Argentina. Electronic address: mboccia@ffyb.uba.ar.

Publikováno v: Neuroscience [Neuroscience] 2022 Aug 10; Vol. 497, pp. 73-85. Date of Electronic Publication: 2022 Jun 22.

Human Astrocytes Exhibit Tumor Microenvironment-, Age-, and Sex-Related Transcriptomic Signatures.

Autor: Krawczyk MC; Department of Psychiatry and Biobehavioral Sciences, Intellectual and Developmental Disabilities Research Center, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, California, 90024., Haney JR; Department of Psychiatry and Biobehavioral Sciences, Intellectual and Developmental Disabilities Research Center, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, California, 90024., Pan L; Department of Psychiatry and Biobehavioral Sciences, Intellectual and Developmental Disabilities Research Center, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, California, 90024., Caneda C; Department of Psychiatry and Biobehavioral Sciences, Intellectual and Developmental Disabilities Research Center, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, California, 90024., Khankan RR; Department of Psychiatry and Biobehavioral Sciences, Intellectual and Developmental Disabilities Research Center, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, California, 90024., Reyes SD; Department of Neurosurgery, David Geffen School of Medicine, University of California, Los Angeles, California, 90024., Chang JW; Department of Psychiatry and Biobehavioral Sciences, Intellectual and Developmental Disabilities Research Center, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, California, 90024.; Department of Neurosurgery, David Geffen School of Medicine, University of California, Los Angeles, California, 90024., Morselli M; Department of Molecular, Cell and Developmental Biology, UCLA-DOE Institute for Genomics and Proteomics, Institute for Quantitative and Computational Biosciences - The Collaboratory at University of California, Los Angeles, California, 90024., Vinters HV; Department of Pathology and Lab Medicine (Neuropathology) and Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, California, 90024.; Ronald Reagan UCLA Medical Center, Los Angeles, California, 90024., Wang AC; Department of Neurosurgery, David Geffen School of Medicine, University of California, Los Angeles, California, 90024., Cobos I; Department of Pathology, Stanford University, Stanford, California, 94305., Gandal MJ; Department of Psychiatry and Biobehavioral Sciences, Intellectual and Developmental Disabilities Research Center, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, California, 90024.; Program in Neurobehavioral Genetics, Semel Institute, David Geffen School of Medicine; Department of Human Genetics, David Geffen School of Medicine at UCLA, Los Angeles, California, 90024., Bergsneider M; Department of Neurosurgery, David Geffen School of Medicine, University of California, Los Angeles, California, 90024., Kim W; Department of Neurosurgery, David Geffen School of Medicine, University of California, Los Angeles, California, 90024., Liau LM; Department of Neurosurgery, David Geffen School of Medicine, University of California, Los Angeles, California, 90024.; Jonsson Comprehensive Cancer Center at UCLA, Los Angeles, California, 90024., Yong W; Department of Pathology, University of California, Irvine, California, 90095., Jalali A; Department of Neurosurgery, Baylor College of Medicine, Houston, Texas, 77030., Deneen B; Department of Neurosurgery, Baylor College of Medicine, Houston, Texas, 77030.; Center for Cell and Gene Therapy, Department of Neuroscience, Department of Neurosurgery, Baylor College of Medicine, Houston, Texas, 77030., Grant GA; Department of Neurosurgery, Stanford University, Stanford, California, 94305., Mathern GW; Department of Psychiatry and Biobehavioral Sciences, Intellectual and Developmental Disabilities Research Center, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, California, 90024.; Department of Neurosurgery, David Geffen School of Medicine, University of California, Los Angeles, California, 90024., Fallah A; Department of Neurosurgery, David Geffen School of Medicine, University of California, Los Angeles, California, 90024., Zhang Y; Department of Psychiatry and Biobehavioral Sciences, Intellectual and Developmental Disabilities Research Center, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, California, 90024 yezhang@ucla.edu.; Brain Research Institute at UCLA, Los Angeles, California, 90095.; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA, Los Angeles, California, 90095.; Molecular Biology Institute at UCLA, Los Angeles, California, 90095.

Publikováno v: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2022 Feb 23; Vol. 42 (8), pp. 1587-1603. Date of Electronic Publication: 2022 Jan 05.