Forced vital capacity trajectories in patients with idiopathic pulmonary fibrosis: a secondary analysis of a multicentre, prospective, observational cohort

Autor: Fainberg, HP, Oldham, JM, Molyneau, PL, Allen, RJ, Kraven, LM, Fahy, WA, Porte, J, Braybrooke, R, Saini, G, Karsdal, MA, Leeming, DJ, Sand, JMB, Triguero, I, Oballa, E, Wells, AU, Renzoni, E, Wain, LV, Noth, I, Maher, TM, Stewart, ID, Jenkins, RG

Publikováno v: e872
e862

Background Idiopathic pulmonary fibrosis is a progressive fibrotic lung disease with a variable clinical trajectory. Decline in forced vital capacity (FVC) is the main indicator of progression; however, missingness prevents long-term analysis of patt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62c323f869c37734f613aed9b1f1798d
https://doi.org/10.1016/s2589-7500(22)00173-x

The Use of Genetic Information to Define Idiopathic Pulmonary Fibrosis in UK Biobank.

Autor: Leavy OC; Department of Health Sciences, University of Leicester, Leicester, England., Allen RJ; Department of Health Sciences, University of Leicester, Leicester, England., Kraven LM; Department of Health Sciences, University of Leicester, Leicester, England., Morgan AD; National Heart and Lung Institute, Imperial College London, London, England., Tobin MD; Department of Health Sciences, University of Leicester, Leicester, England; National Institute for Health Research, Leicester Respiratory Biomedical Research Centre, Glenfield Hospital, Leicester, England., Quint JK; National Heart and Lung Institute, Imperial College London, London, England., Jenkins RG; National Heart and Lung Institute, Imperial College London, London, England., Wain LV; Department of Health Sciences, University of Leicester, Leicester, England; National Institute for Health Research, Leicester Respiratory Biomedical Research Centre, Glenfield Hospital, Leicester, England. Electronic address: louisewain@le.ac.uk.

Publikováno v: Chest [Chest] 2023 Feb; Vol. 163 (2), pp. 362-365. Date of Electronic Publication: 2022 Aug 25.

Genetic overlap between idiopathic pulmonary fibrosis and COVID-19.

Autor: Allen RJ; Department of Health Sciences, University of Leicester, Leicester, UK rja34@leicester.ac.uk.; These authors contributed equally., Guillen-Guio B; Department of Health Sciences, University of Leicester, Leicester, UK.; These authors contributed equally., Croot E; Department of Genetics and Genome Biology, University of Leicester, Leicester, UK., Kraven LM; Department of Health Sciences, University of Leicester, Leicester, UK., Moss S; National Heart and Lung Institute, Imperial College London, London, UK., Stewart I; National Heart and Lung Institute, Imperial College London, London, UK., Jenkins RG; National Heart and Lung Institute, Imperial College London, London, UK., Wain LV; Department of Health Sciences, University of Leicester, Leicester, UK.; National Institute for Health Research, Leicester Respiratory Biomedical Research Centre, Glenfield Hospital, Leicester, UK.

Publikováno v: The European respiratory journal [Eur Respir J] 2022 Jul 07; Vol. 60 (1). Date of Electronic Publication: 2022 Jul 07 (Print Publication: 2022).

Genome-Wide Association Study of Susceptibility to Idiopathic Pulmonary Fibrosis.

Autor: Allen RJ; Department of Health Sciences, University of Leicester, Leicester, United Kingdom., Guillen-Guio B; Unidad de Investigacion, Hospital Universitario Ntra. Sra. de Candelaria and., Oldham JM; Department of Internal Medicine, University of California Davis, Davis, California., Ma SF; Division of Pulmonary and Critical Care Medicine., Dressen A; Genentech, South San Francisco, California., Paynton ML; Department of Health Sciences, University of Leicester, Leicester, United Kingdom., Kraven LM; Department of Health Sciences, University of Leicester, Leicester, United Kingdom., Obeidat M; The University of British Columbia Centre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada., Li X; The University of British Columbia Centre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada., Ng M; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences., Braybrooke R; Division of Epidemiology and Public Health and.; National Institute for Health Research, Nottingham Biomedical Research Centre and., Molina-Molina M; Servei de Pneumologia, Laboratori de Pneumologia Experimental, Instituto de Investigación Biomédica de Bellvitge (IDIBELL), Barcelona, Spain.; Campus de Bellvitge, Universitat de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain., Hobbs BD; Channing Division of Network Medicine.; Division of Pulmonary and Critical Care Medicine., Putman RK; Division of Pulmonary and Critical Care Medicine., Sakornsakolpat P; Channing Division of Network Medicine.; Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand., Booth HL; Department of Thoracic Medicine, University College London Hospitals NHS Foundation Trust, London, United Kingdom., Fahy WA; Discovery Medicine, GlaxoSmithKline, Stevenage, United Kingdom., Hart SP; Respiratory Research Group, Hull York Medical School, Castle Hill Hospital, Cottingham, United Kingdom., Hill MR; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health., Hirani N; Medical Research Council Centre for Inflammation Research, The University of Edinburgh, Edinburgh, United Kingdom., Hubbard RB; Division of Epidemiology and Public Health and.; National Institute for Health Research, Nottingham Biomedical Research Centre and., McAnulty RJ; UCL Respiratory Centre for Inflammation and Tissue Repair, University College London, London, United Kingdom., Millar AB; Academic Respiratory Unit, School of Clinical Sciences, University of Bristol, Bristol, United Kingdom., Navaratnam V; Division of Epidemiology and Public Health and.; National Institute for Health Research, Nottingham Biomedical Research Centre and., Oballa E; Discovery Medicine, GlaxoSmithKline, Stevenage, United Kingdom., Parfrey H; Cambridge Interstitial Lung Disease Service, Royal Papworth Hospital, Cambridge, United Kingdom., Saini G; Respiratory Medicine, Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom., Whyte MKB; Medical Research Council Centre for Inflammation Research, The University of Edinburgh, Edinburgh, United Kingdom., Zhang Y; Division of Pulmonary, Allergy and Critical Care Medicine and.; Simmons Center for Interstitial Lung Diseases, University of Pittsburgh, Pittsburgh, Pennsylvania., Kaminski N; Section of Pulmonary, Critical Care and Sleep Medicine, Yale School of Medicine, New Haven, Connecticut., Adegunsoye A; Section of Pulmonary and Critical Care, Department of Medicine, The University of Chicago, Chicago, Illinois., Strek ME; Section of Pulmonary and Critical Care, Department of Medicine, The University of Chicago, Chicago, Illinois., Neighbors M; Genentech, South San Francisco, California., Sheng XR; Genentech, South San Francisco, California., Gudmundsson G; Department of Respiratory Medicine, Landspital University Hospital, Reykjavik, Iceland.; Faculty of Medicine University of Iceland, Reykjavik, Iceland., Gudnason V; Faculty of Medicine University of Iceland, Reykjavik, Iceland.; Icelandic Heart Association, Kopavogur, Iceland., Hatabu H; Department of Radiology, and.; Center for Pulmonary Functional Imaging, Brigham and Women's Hospital, Boston, Massachusetts., Lederer DJ; Department of Medicine, College of Physicians and Surgeons and.; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York., Manichaikul A; Center for Public Health Genomics, and.; Department of Public Health Sciences, University of Virginia, Charlottesville, Virginia., Newell JD Jr; Division of Cardiovascular and Pulmonary Imaging, Department of Radiology, University of Iowa Carver College of Medicine, Iowa City, Iowa.; Department of Radiology, University of Washington, Seattle, Washington., O'Connor GT; Department of Medicine, Pulmonary Center, Boston University, Boston, Massachusetts.; NHLBI's Framingham Heart Study, Framingham, Massachusetts., Ortega VE; Center for Precision Medicine, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina., Xu H; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts., Fingerlin TE; Center for Genes, Environment and Health, National Jewish Health, Denver, Colarado.; Department of Biostatistics and Informatics., Bossé Y; Institut universitaire de cardiologie et de pneumologie de Québec, Université Laval, Québec, Québec, Canada., Hao K; Department of Genetics and Genomic Sciences and.; Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, New York., Joubert P; Institut universitaire de cardiologie et de pneumologie de Québec, Université Laval, Québec, Québec, Canada., Nickle DC; Merck Research Laboratories, Genetics and Pharmacogenomics, Boston, Massachusetts., Sin DD; The University of British Columbia Centre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.; Respiratory Division, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada., Timens W; University Medical Center Groningen, University of Groningen, Department of Pathology and Medical Biology and.; Groningen Research Institute for Asthma and COPD, Groningen, the Netherlands., Furniss D; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences., Morris AP; Wellcome Centre for Human Genetics, and.; Department of Biostatistics, University of Liverpool, Liverpool, United Kingdom.; Division of Musculoskeletal and Dermatological Sciences, University of Manchester, Manchester, United Kingdom., Zondervan KT; Wellcome Centre for Human Genetics, and.; Oxford Endometriosis Care and Research Centre, Nuffield Department of Women's and Reproductive Health, University of Oxford, Oxford, United Kingdom., Hall IP; Division of Respiratory Medicine, University of Nottingham, Nottingham, United Kingdom.; National Institute for Health Research, Nottingham Biomedical Research Centre and., Sayers I; Division of Respiratory Medicine, University of Nottingham, Nottingham, United Kingdom.; National Institute for Health Research, Nottingham Biomedical Research Centre and., Tobin MD; Department of Health Sciences, University of Leicester, Leicester, United Kingdom.; National Institute for Health Research, Leicester Respiratory Biomedical Research Centre, Glenfield Hospital, Leicester, United Kingdom., Maher TM; National Institute for Health Research Respiratory Clinical Research Facility, Royal Brompton Hospital, London, United Kingdom.; National Heart and Lung Institute, Imperial College, London, United Kingdom; and., Cho MH; Channing Division of Network Medicine.; Division of Pulmonary and Critical Care Medicine., Hunninghake GM; Division of Pulmonary and Critical Care Medicine.; Center for Pulmonary Functional Imaging, Brigham and Women's Hospital, Boston, Massachusetts., Schwartz DA; Center for Genes, Environment and Health, National Jewish Health, Denver, Colarado.; Department of Medicine, and.; Department of Immunology, University of Colorado Denver, Denver, Colorado., Yaspan BL; Genentech, South San Francisco, California., Molyneaux PL; National Institute for Health Research Respiratory Clinical Research Facility, Royal Brompton Hospital, London, United Kingdom.; National Heart and Lung Institute, Imperial College, London, United Kingdom; and., Flores C; Unidad de Investigacion, Hospital Universitario Ntra. Sra. de Candelaria and.; Instituto de Tecnologías Biomédicas, Universidad de La Laguna, Santa Cruz de Tenerife, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain.; Instituto Tecnológico y de Energías Renovables, S.A., Santa Cruz de Tenerife, Spain., Noth I; Division of Pulmonary and Critical Care Medicine., Jenkins RG; Division of Respiratory Medicine, University of Nottingham, Nottingham, United Kingdom.; National Institute for Health Research, Nottingham Biomedical Research Centre and., Wain LV; Department of Health Sciences, University of Leicester, Leicester, United Kingdom.; National Institute for Health Research, Leicester Respiratory Biomedical Research Centre, Glenfield Hospital, Leicester, United Kingdom.

Publikováno v: American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2020 Mar 01; Vol. 201 (5), pp. 564-574.