Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Kratschmar DV"'
Autor:
Trevor M. Penning, Laura Gathercole, Michael F. Saikali, Kratschmar Dv, Shelley Harris, Roger D. Cox, Ahmad Moolla, Jonathan Hazlehurst, Liz Bentley, Ryan C. Pink, Jeremy W. Tomlinson, Toryn Poolman, Nikolaos Nikolaou, Niall Dempster, Alex Odermatt, Claes Ohlsson, Matti Poutanen, Anastasia Arvaniti, Carolyn L. Cummins, Marijana Todorčević
BackgroundSteroid 5β-reductase (AKR1D1) plays important roles in hepatic glucocorticoid clearance and bile acid synthesis. Glucocorticoids and bile acids are potent metabolic regulators, but whether AKR1D1 controls metabolic phenotype in vivo is unk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b696683522dd09fab5fd3b09f895111
https://doi.org/10.1101/2021.02.02.429227
https://doi.org/10.1101/2021.02.02.429227
Autor:
Gathercole LL; Oxford Centre for Diabetes, Endocrinology and Metabolism, NIHR Oxford Biomedical Research Centre, University of Oxford, Churchill Hospital, Oxford, UK.; Department of Biological and Medical Sciences, Oxford Brookes University, Oxford, UK., Nikolaou N; Oxford Centre for Diabetes, Endocrinology and Metabolism, NIHR Oxford Biomedical Research Centre, University of Oxford, Churchill Hospital, Oxford, UK., Harris SE; Oxford Centre for Diabetes, Endocrinology and Metabolism, NIHR Oxford Biomedical Research Centre, University of Oxford, Churchill Hospital, Oxford, UK., Arvaniti A; Oxford Centre for Diabetes, Endocrinology and Metabolism, NIHR Oxford Biomedical Research Centre, University of Oxford, Churchill Hospital, Oxford, UK.; Department of Biological and Medical Sciences, Oxford Brookes University, Oxford, UK., Poolman TM; Oxford Centre for Diabetes, Endocrinology and Metabolism, NIHR Oxford Biomedical Research Centre, University of Oxford, Churchill Hospital, Oxford, UK., Hazlehurst JM; Oxford Centre for Diabetes, Endocrinology and Metabolism, NIHR Oxford Biomedical Research Centre, University of Oxford, Churchill Hospital, Oxford, UK.; Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK., Kratschmar DV; Swiss Centre for Applied Human Toxicology and Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland., Todorčević M; Oxford Centre for Diabetes, Endocrinology and Metabolism, NIHR Oxford Biomedical Research Centre, University of Oxford, Churchill Hospital, Oxford, UK., Moolla A; Oxford Centre for Diabetes, Endocrinology and Metabolism, NIHR Oxford Biomedical Research Centre, University of Oxford, Churchill Hospital, Oxford, UK., Dempster N; Oxford Centre for Diabetes, Endocrinology and Metabolism, NIHR Oxford Biomedical Research Centre, University of Oxford, Churchill Hospital, Oxford, UK., Pink RC; Department of Biological and Medical Sciences, Oxford Brookes University, Oxford, UK., Saikali MF; Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada., Bentley L; Mammalian Genetics Unit, Medical Research Council Harwell, Oxford, UK., Penning TM; Center of Excellence in Environmental Toxicology, Department of Systems Pharmacology & Translational Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Ohlsson C; Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Cummins CL; Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada., Poutanen M; Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Institute of Biomedicine, Research Centre for Integrative Physiology and Pharmacology, University of Turku, Turku, Finland., Odermatt A; Swiss Centre for Applied Human Toxicology and Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland., Cox RD; Mammalian Genetics Unit, Medical Research Council Harwell, Oxford, UK., Tomlinson JW; Oxford Centre for Diabetes, Endocrinology and Metabolism, NIHR Oxford Biomedical Research Centre, University of Oxford, Churchill Hospital, Oxford, UK.
Publikováno v:
The Journal of endocrinology [J Endocrinol] 2022 Apr 13; Vol. 253 (3), pp. 97-113. Date of Electronic Publication: 2022 Apr 13.
Autor:
Banki E; Institute of Anatomy, University of Zurich, Zurich, Switzerland; Swiss National Centre for Competence in Research 'Kidney Control of Homeostasis,' Zurich, Switzerland., Fisi V; Institute of Anatomy, University of Zurich, Zurich, Switzerland., Moser S; Institute of Anatomy, University of Zurich, Zurich, Switzerland., Wengi A; Institute of Anatomy, University of Zurich, Zurich, Switzerland., Carrel M; Institute of Anatomy, University of Zurich, Zurich, Switzerland., Loffing-Cueni D; Institute of Anatomy, University of Zurich, Zurich, Switzerland., Penton D; Institute of Anatomy, University of Zurich, Zurich, Switzerland; Swiss National Centre for Competence in Research 'Kidney Control of Homeostasis,' Zurich, Switzerland., Kratschmar DV; Department of Pharmaceutical Sciences, Division of Molecular and Systems Toxicology, University of Basel, Basel, Switzerland., Rizzo L; Institute of Anatomy, University of Zurich, Zurich, Switzerland., Lienkamp S; Institute of Anatomy, University of Zurich, Zurich, Switzerland; Swiss National Centre for Competence in Research 'Kidney Control of Homeostasis,' Zurich, Switzerland., Odermatt A; Department of Pharmaceutical Sciences, Division of Molecular and Systems Toxicology, University of Basel, Basel, Switzerland., Rinschen MM; Kidney Research Center, University of Cologne, Köln, Germany; Department of Biomedicine, Aarhus University, Aarhus, Denmark; III Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Loffing J; Institute of Anatomy, University of Zurich, Zurich, Switzerland; Swiss National Centre for Competence in Research 'Kidney Control of Homeostasis,' Zurich, Switzerland. Electronic address: johannes.loffing@anatomy.uzh.ch.
Publikováno v:
Kidney international [Kidney Int] 2021 Oct; Vol. 100 (4), pp. 850-869. Date of Electronic Publication: 2021 Jul 10.
Autor:
Weingartner M; Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland., Stücheli S; Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland., Kratschmar DV; Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland., Birk J; Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland., Klusonova P; Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland., Chapman KE; Queen's Medical Research Institute, University/BHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK., Lavery GG; Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK., Odermatt A; Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland.
Publikováno v:
British journal of pharmacology [Br J Pharmacol] 2021 Aug; Vol. 178 (16), pp. 3309-3326. Date of Electronic Publication: 2021 Feb 04.
Autor:
Schnoz C; Institute of Anatomy, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland., Moser S; Institute of Anatomy, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland., Kratschmar DV; Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland., Odermatt A; Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland.; National Centre of Competence in Research 'Kidney.CH', University of Zurich, 8057, Zurich, Switzerland., Loffing-Cueni D; Institute of Anatomy, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland., Loffing J; Institute of Anatomy, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland. johannes.loffing@anatomy.uzh.ch.; National Centre of Competence in Research 'Kidney.CH', University of Zurich, 8057, Zurich, Switzerland. johannes.loffing@anatomy.uzh.ch.
Publikováno v:
Pflugers Archiv : European journal of physiology [Pflugers Arch] 2021 Jan; Vol. 473 (1), pp. 79-93. Date of Electronic Publication: 2020 Nov 16.
Autor:
Gómez C; Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Klingelbergstrasse 50, 4056 Basel, Switzerland., Stücheli S; Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Klingelbergstrasse 50, 4056 Basel, Switzerland., Kratschmar DV; Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Klingelbergstrasse 50, 4056 Basel, Switzerland., Bouitbir J; Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Klingelbergstrasse 50, 4056 Basel, Switzerland., Odermatt A; Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Klingelbergstrasse 50, 4056 Basel, Switzerland.
Publikováno v:
Metabolites [Metabolites] 2020 Jul 09; Vol. 10 (7). Date of Electronic Publication: 2020 Jul 09.
Autor:
Lizák B; Department of Medical Chemistry, Molecular Biology and Pathobiochemistry, Semmelweis University, Budapest, Hungary. lizak.beata@med.semmelweis-univ.hu., Birk J; Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Klingelbergstrasse 50, 4056, Basel, Switzerland., Zana M; Department of Physiology, Faculty of Medicine, Semmelweis University, Budapest, Hungary.; 'Momentum' Peroxidase Enzyme Research Group of the Semmelweis University and the Hungarian Academy of Sciences, Budapest, Hungary., Kosztyi G; Department of Medical Chemistry, Molecular Biology and Pathobiochemistry, Semmelweis University, Budapest, Hungary., Kratschmar DV; Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Klingelbergstrasse 50, 4056, Basel, Switzerland., Odermatt A; Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Klingelbergstrasse 50, 4056, Basel, Switzerland., Zimmermann R; Medical Biochemistry and Molecular Biology, Saarland University, 66421, Homburg, Germany., Geiszt M; Department of Physiology, Faculty of Medicine, Semmelweis University, Budapest, Hungary.; 'Momentum' Peroxidase Enzyme Research Group of the Semmelweis University and the Hungarian Academy of Sciences, Budapest, Hungary., Appenzeller-Herzog C; Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Klingelbergstrasse 50, 4056, Basel, Switzerland. christian.appenzeller@unibas.ch.; University Medical Library, University of Basel, Spiegelgasse 5, 4051, Basel, Switzerland. christian.appenzeller@unibas.ch., Bánhegyi G; Department of Medical Chemistry, Molecular Biology and Pathobiochemistry, Semmelweis University, Budapest, Hungary.
Publikováno v:
BMC biology [BMC Biol] 2020 Feb 26; Vol. 18 (1), pp. 19. Date of Electronic Publication: 2020 Feb 26.
Autor:
Schulze F; Clinic of Endocrinology, Diabetes and Metabolism, University Hospital Basel, Basel, Switzerland and Department of Biomedicine, University of Basel, Basel, Switzerland. schulze.fritzi@gmail.com., Wehner J; Clinic of Endocrinology, Diabetes and Metabolism, University Hospital Basel, Basel, Switzerland and Department of Biomedicine, University of Basel, Basel, Switzerland., Kratschmar DV; Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland., Makshana V; Clinic of Endocrinology, Diabetes and Metabolism, University Hospital Basel, Basel, Switzerland and Department of Biomedicine, University of Basel, Basel, Switzerland., Meier DT; Clinic of Endocrinology, Diabetes and Metabolism, University Hospital Basel, Basel, Switzerland and Department of Biomedicine, University of Basel, Basel, Switzerland., Häuselmann SP; Clinic of Endocrinology, Diabetes and Metabolism, University Hospital Basel, Basel, Switzerland and Department of Biomedicine, University of Basel, Basel, Switzerland., Dalmas E; Clinic of Endocrinology, Diabetes and Metabolism, University Hospital Basel, Basel, Switzerland and Department of Biomedicine, University of Basel, Basel, Switzerland., Thienel C; Clinic of Endocrinology, Diabetes and Metabolism, University Hospital Basel, Basel, Switzerland and Department of Biomedicine, University of Basel, Basel, Switzerland., Dror E; Clinic of Endocrinology, Diabetes and Metabolism, University Hospital Basel, Basel, Switzerland and Department of Biomedicine, University of Basel, Basel, Switzerland., Wiedemann SJ; Clinic of Endocrinology, Diabetes and Metabolism, University Hospital Basel, Basel, Switzerland and Department of Biomedicine, University of Basel, Basel, Switzerland., Traub S; Clinic of Endocrinology, Diabetes and Metabolism, University Hospital Basel, Basel, Switzerland and Department of Biomedicine, University of Basel, Basel, Switzerland., Nordmann TM; Clinic of Endocrinology, Diabetes and Metabolism, University Hospital Basel, Basel, Switzerland and Department of Biomedicine, University of Basel, Basel, Switzerland., Rachid L; Clinic of Endocrinology, Diabetes and Metabolism, University Hospital Basel, Basel, Switzerland and Department of Biomedicine, University of Basel, Basel, Switzerland., De Baat A; Clinic of Endocrinology, Diabetes and Metabolism, University Hospital Basel, Basel, Switzerland and Department of Biomedicine, University of Basel, Basel, Switzerland., Rohm TV; Clinic of Endocrinology, Diabetes and Metabolism, University Hospital Basel, Basel, Switzerland and Department of Biomedicine, University of Basel, Basel, Switzerland., Zhao C; Clinic of Endocrinology, Diabetes and Metabolism, University Hospital Basel, Basel, Switzerland and Department of Biomedicine, University of Basel, Basel, Switzerland., Odermatt A; Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland., Böni-Schnetzler M; Clinic of Endocrinology, Diabetes and Metabolism, University Hospital Basel, Basel, Switzerland and Department of Biomedicine, University of Basel, Basel, Switzerland., Donath MY; Clinic of Endocrinology, Diabetes and Metabolism, University Hospital Basel, Basel, Switzerland and Department of Biomedicine, University of Basel, Basel, Switzerland.
Publikováno v:
Scientific reports [Sci Rep] 2020 Feb 20; Vol. 10 (1), pp. 3035. Date of Electronic Publication: 2020 Feb 20.
Autor:
Keppner A; Department of Pharmacology and Toxicology, University of Lausanne, Lausanne, Switzerland.; Department of Medicine/Physiology, University of Fribourg, Fribourg, Switzerland.; National Center of Competence in Research Kidney Control of Homeostasis (NCCR Kidney.CH), University of Lausanne, Lausanne, Switzerland., Maric D; Department of Pharmacology and Toxicology, University of Lausanne, Lausanne, Switzerland.; Department of Medicine/Physiology, University of Fribourg, Fribourg, Switzerland.; National Center of Competence in Research Kidney Control of Homeostasis (NCCR Kidney.CH), University of Lausanne, Lausanne, Switzerland., Sergi C; Department of Pharmacology and Toxicology, University of Lausanne, Lausanne, Switzerland., Ansermet C; Department of Pharmacology and Toxicology, University of Lausanne, Lausanne, Switzerland., De Bellis D; Department of Pharmacology and Toxicology, University of Lausanne, Lausanne, Switzerland.; Electron Microscopy Facility, University of Lausanne, Lausanne, Switzerland.; Department of Plant Molecular Biology, University of Lausanne, Lausanne, Switzerland., Kratschmar DV; Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland.; National Center of Competence in Research Kidney Control of Homeostasis (NCCR Kidney.CH), University of Lausanne, Lausanne, Switzerland., Canonica J; Department of Pharmacology and Toxicology, University of Lausanne, Lausanne, Switzerland.; National Center of Competence in Research Kidney Control of Homeostasis (NCCR Kidney.CH), University of Lausanne, Lausanne, Switzerland.; Ophthalmic Hospital Jules Gonin, University of Lausanne, Lausanne, Switzerland., Klusonova P; Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland.; National Center of Competence in Research Kidney Control of Homeostasis (NCCR Kidney.CH), University of Lausanne, Lausanne, Switzerland., Fenton RA; Department of Biomedicine, Aarhus University, Aarhus, Denmark., Odermatt A; Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland.; National Center of Competence in Research Kidney Control of Homeostasis (NCCR Kidney.CH), University of Lausanne, Lausanne, Switzerland., Crambert G; INSERM, Paris, France., Hoogewijs D; Department of Medicine/Physiology, University of Fribourg, Fribourg, Switzerland.; National Center of Competence in Research Kidney Control of Homeostasis (NCCR Kidney.CH), University of Lausanne, Lausanne, Switzerland., Hummler E; Department of Pharmacology and Toxicology, University of Lausanne, Lausanne, Switzerland. Edith.Hummler@unil.ch.; National Center of Competence in Research Kidney Control of Homeostasis (NCCR Kidney.CH), University of Lausanne, Lausanne, Switzerland. Edith.Hummler@unil.ch.
Publikováno v:
Scientific reports [Sci Rep] 2019 Dec 20; Vol. 9 (1), pp. 19540. Date of Electronic Publication: 2019 Dec 20.
Autor:
Trinh B; Department of Endocrinology, Diabetes and Metabolism, University Hospital Basel, and Department of Biomedicine, University of Basel, Basel, Switzerland., Hepprich M; Department of Endocrinology, Diabetes and Metabolism, University Hospital Basel, and Department of Biomedicine, University of Basel, Basel, Switzerland., Betz MJ; Department of Endocrinology, Diabetes and Metabolism, University Hospital Basel, and Department of Biomedicine, University of Basel, Basel, Switzerland., Burkard T; European Society of Hypertension Centre of Excellence, Medical Outpatient Department, and Department of Cardiology, University Hospital Basel, Basel, Switzerland., Cavelti-Weder C; Department of Endocrinology, Diabetes and Metabolism, University Hospital Basel, and Department of Biomedicine, University of Basel, Basel, Switzerland., Seelig E; Department of Endocrinology, Diabetes and Metabolism, University Hospital Basel, and Department of Biomedicine, University of Basel, Basel, Switzerland., Meienberg F; Clinic of Endocrinology and Diabetology, Kantonsspital Baselland, Liestal, Switzerland., Kratschmar DV; Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland., Beuschlein F; Klinik für Endokrinologie, Diabetologie und Klinische Ernährung, Universitätsspital Zürich, Zürich, Switzerland.; Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, Munich, Germany., Reincke M; Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, Munich, Germany., Odermatt A; Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland., Hall MN; Biozentrum, University of Basel, Basel, Switzerland., Donath MY; Department of Endocrinology, Diabetes and Metabolism, University Hospital Basel, and Department of Biomedicine, University of Basel, Basel, Switzerland., Swierczynska MM; Biozentrum, University of Basel, Basel, Switzerland.
Publikováno v:
The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2019 Oct 01; Vol. 104 (10), pp. 4703-4714.