Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Kramer NJ"'
Publikováno v:
Neuron
Parkinson's disease (PD) is a common neurodegenerative disorder. Functional interactions between some PD genes like PINK1 and parkin have been identified but whether other ones interact remains elusive. Here we report an unexpected genetic interactio
Autor:
Kramer NJ; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA., Prakash G; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA., Isaac RS; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA., Choquet K; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA., Soto I; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA., Petrova B; Department of Pathology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Merens HE; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA., Kanarek N; Department of Pathology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Churchman LS; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA. churchman@genetics.med.harvard.edu.
Publikováno v:
Nature cell biology [Nat Cell Biol] 2023 Nov; Vol. 25 (11), pp. 1575-1589. Date of Electronic Publication: 2023 Sep 28.
Autor:
Goodman LD; Neuroscience Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Prudencio M; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Kramer NJ; Neuroscience Graduate Program, Stanford University School of Medicine, Stanford, CA, USA., Martinez-Ramirez LF; Department of Biology, University of Pennsylvania, Philadelphia, PA, USA., Srinivasan AR; Department of Biology, University of Pennsylvania, Philadelphia, PA, USA., Lan M; Department of Biology, University of Pennsylvania, Philadelphia, PA, USA., Parisi MJ; Department of Biology, University of Pennsylvania, Philadelphia, PA, USA., Zhu Y; Department of Biology, University of Pennsylvania, Philadelphia, PA, USA., Chew J; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Cook CN; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Berson A; Department of Biology, University of Pennsylvania, Philadelphia, PA, USA., Gitler AD; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Petrucelli L; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Bonini NM; Neuroscience Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. nbonini@sas.upenn.edu.; Department of Biology, University of Pennsylvania, Philadelphia, PA, USA. nbonini@sas.upenn.edu.
Publikováno v:
Nature neuroscience [Nat Neurosci] 2023 Mar; Vol. 26 (3), pp. 528.
Publikováno v:
BioRxiv : the preprint server for biology [bioRxiv] 2023 Feb 11. Date of Electronic Publication: 2023 Feb 11.
Autor:
Rice AJ; Department of Chemistry, University of Illinois at Urbana-Champaign, 600 South Mathews Avenue, Urbana, Illinois 61801, United States.; Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, 1206 West Gregory Drive, Urbana, Illinois 61801, United States., Pelton JM; Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, 301 Pharmacy Lane, Chapel Hill, North Carolina 27599, United States., Kramer NJ; Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, 301 Pharmacy Lane, Chapel Hill, North Carolina 27599, United States., Catlin DS; Department of Biochemistry, Center for Biophysics and Quantitative Biology, University of Illinois, Urbana, Illinois 61801, United States., Nair SK; Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, 1206 West Gregory Drive, Urbana, Illinois 61801, United States.; Department of Biochemistry, Center for Biophysics and Quantitative Biology, University of Illinois, Urbana, Illinois 61801, United States., Pogorelov TV; Department of Chemistry, University of Illinois at Urbana-Champaign, 600 South Mathews Avenue, Urbana, Illinois 61801, United States.; School of Chemical Sciences, University of Illinois at Urbana-Champaign, 505 South Mathews Avenue, Urbana, Illinois 61801, United States.; National Center for Supercomputing Applications, University of Illinois at Urbana-Champaign, 1205 West Clark Street, Urbana, Illinois 61801, United States.; Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, 405 North Mathews Avenue, Urbana, Illinois 61801, United States., Mitchell DA; Department of Chemistry, University of Illinois at Urbana-Champaign, 600 South Mathews Avenue, Urbana, Illinois 61801, United States.; Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, 1206 West Gregory Drive, Urbana, Illinois 61801, United States.; Department of Microbiology, University of Illinois at Urbana-Champaign, 600 South Mathews Avenue, Urbana, Illinois 61801, United States., Bowers AA; Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, 301 Pharmacy Lane, Chapel Hill, North Carolina 27599, United States.; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.
Publikováno v:
Journal of the American Chemical Society [J Am Chem Soc] 2022 Nov 23; Vol. 144 (46), pp. 21116-21124. Date of Electronic Publication: 2022 Nov 09.
Autor:
Cadilla R; GlaxoSmithKline, 5 Moore Drive, P.O. Box 13398, Research Triangle Park, NC 27709, USA., Deaton DN; GlaxoSmithKline, 5 Moore Drive, P.O. Box 13398, Research Triangle Park, NC 27709, USA. Electronic address: david.n.deaton@gsk.com., Do Y; GlaxoSmithKline, 5 Moore Drive, P.O. Box 13398, Research Triangle Park, NC 27709, USA., Elkins PA; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, PA 19426, USA., Ennulat D; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, PA 19426, USA., Guss JH; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, PA 19426, USA., Holt J; GlaxoSmithKline, 5 Moore Drive, P.O. Box 13398, Research Triangle Park, NC 27709, USA., Jeune MR; GlaxoSmithKline, 5 Moore Drive, P.O. Box 13398, Research Triangle Park, NC 27709, USA., King AG; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, PA 19426, USA., Klapwijk JC; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, PA 19426, USA., Kramer HF; GlaxoSmithKline, 5 Moore Drive, P.O. Box 13398, Research Triangle Park, NC 27709, USA., Kramer NJ; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, PA 19426, USA., Laffan SB; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, PA 19426, USA., Masuria PI; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, PA 19426, USA., McDougal AV; GlaxoSmithKline, 5 Moore Drive, P.O. Box 13398, Research Triangle Park, NC 27709, USA., Mortenson PN; Astex Pharmaceuticals, 436 Cambridge Science Park, Milton Road, Cambridge CB4 0QA, UK., Musetti C; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, PA 19426, USA., Peckham GE; GlaxoSmithKline, 5 Moore Drive, P.O. Box 13398, Research Triangle Park, NC 27709, USA., Pietrak BL; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, PA 19426, USA., Poole C; GlaxoSmithKline, 5 Moore Drive, P.O. Box 13398, Research Triangle Park, NC 27709, USA., Price DJ; GlaxoSmithKline, 5 Moore Drive, P.O. Box 13398, Research Triangle Park, NC 27709, USA., Rendina AR; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, PA 19426, USA., Sati G; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, PA 19426, USA., Saxty G; Astex Pharmaceuticals, 436 Cambridge Science Park, Milton Road, Cambridge CB4 0QA, UK., Shearer BG; GlaxoSmithKline, 5 Moore Drive, P.O. Box 13398, Research Triangle Park, NC 27709, USA., Shewchuk LM; GlaxoSmithKline, 5 Moore Drive, P.O. Box 13398, Research Triangle Park, NC 27709, USA., Sneddon HF; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, UK., Stewart EL; GlaxoSmithKline, 5 Moore Drive, P.O. Box 13398, Research Triangle Park, NC 27709, USA., Stuart JD; GlaxoSmithKline, 5 Moore Drive, P.O. Box 13398, Research Triangle Park, NC 27709, USA., Thomas DN; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, PA 19426, USA., Thomson SA; GlaxoSmithKline, 5 Moore Drive, P.O. Box 13398, Research Triangle Park, NC 27709, USA., Ward P; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, PA 19426, USA., Wilson JW; GlaxoSmithKline, 5 Moore Drive, P.O. Box 13398, Research Triangle Park, NC 27709, USA., Xu T; GlaxoSmithKline, 5 Moore Drive, P.O. Box 13398, Research Triangle Park, NC 27709, USA., Youngman MA; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, PA 19426, USA.
Publikováno v:
Bioorganic & medicinal chemistry [Bioorg Med Chem] 2020 Dec 01; Vol. 28 (23), pp. 115791. Date of Electronic Publication: 2020 Oct 03.
Autor:
Tang R; Department of Genetics, Stanford University School of Medicine, Stanford, United States., Murray CW; Cancer Biology Program, Stanford University School of Medicine, Stanford, United States., Linde IL; Immunology Program, Stanford University School of Medicine, Stanford, United States., Kramer NJ; Department of Genetics, Stanford University School of Medicine, Stanford, United States.; Neuroscience Program, Stanford University School of Medicine, Stanford, United States., Lyu Z; Department of Neurosurgery, Stanford University School of Medicine, Stanford, United States., Tsai MK; Department of Genetics, Stanford University School of Medicine, Stanford, United States., Chen LC; Department of Genetics, Stanford University School of Medicine, Stanford, United States., Cai H; Department of Genetics, Stanford University School of Medicine, Stanford, United States., Gitler AD; Department of Genetics, Stanford University School of Medicine, Stanford, United States., Engleman E; Cancer Biology Program, Stanford University School of Medicine, Stanford, United States.; Immunology Program, Stanford University School of Medicine, Stanford, United States.; Department of Pathology, Stanford University School of Medicine, Stanford, United States., Lee W; Department of Neurosurgery, Stanford University School of Medicine, Stanford, United States., Winslow MM; Department of Genetics, Stanford University School of Medicine, Stanford, United States.; Cancer Biology Program, Stanford University School of Medicine, Stanford, United States.; Department of Pathology, Stanford University School of Medicine, Stanford, United States.
Publikováno v:
ELife [Elife] 2020 Oct 07; Vol. 9. Date of Electronic Publication: 2020 Oct 07.
Autor:
Bogart JW; Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States., Kramer NJ; Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States., Turlik A; Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095, United States., Bleich RM; Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States., Catlin DS; Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States., Schroeder FC; Boyce Thompson Institute and Department of Chemistry and Chemical Biology, Ithaca, New York 14853, United States., Nair SK; Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.; Center for Biophysics and Computational Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States., Williamson RT; Department of Chemistry and Biochemistry, University of North Carolina Wilmington, Wilmington, North Carolina 28403, United States., Houk KN; Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095, United States., Bowers AA; Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.
Publikováno v:
Journal of the American Chemical Society [J Am Chem Soc] 2020 Jul 29; Vol. 142 (30), pp. 13170-13179. Date of Electronic Publication: 2020 Jul 16.
Autor:
Yamada SB; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Department of Biology, Stanford University, Stanford, CA, USA., Gendron TF; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Niccoli T; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.; UK Dementia Research Institute at UCL, UCL Institute of Neurology, London, UK.; Department of Genetics, Evolution and Environment, Institute of Healthy Ageing, University College London, London, UK., Genuth NR; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Department of Biology, Stanford University, Stanford, CA, USA.; Department of Developmental Biology, Stanford University School of Medicine, Stanford, CA, USA., Grosely R; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, USA., Shi Y; Department of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, University of Southern California, Los Angeles, CA, USA., Glaria I; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.; UK Dementia Research Institute at UCL, UCL Institute of Neurology, London, UK., Kramer NJ; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Stanford Neurosciences Graduate Program, Stanford University School of Medicine, Stanford, CA, USA., Nakayama L; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Fang S; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Dinger TJI; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Department of Biology, Stanford University, Stanford, CA, USA., Thoeng A; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.; UK Dementia Research Institute at UCL, UCL Institute of Neurology, London, UK.; Department of Genetics, Evolution and Environment, Institute of Healthy Ageing, University College London, London, UK., Rocha G; Department of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, University of Southern California, Los Angeles, CA, USA., Barna M; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Department of Developmental Biology, Stanford University School of Medicine, Stanford, CA, USA., Puglisi JD; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, USA., Partridge L; Department of Genetics, Evolution and Environment, Institute of Healthy Ageing, University College London, London, UK., Ichida JK; Department of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, University of Southern California, Los Angeles, CA, USA., Isaacs AM; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.; UK Dementia Research Institute at UCL, UCL Institute of Neurology, London, UK., Petrucelli L; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Gitler AD; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA. agitler@stanford.edu.
Publikováno v:
Nature neuroscience [Nat Neurosci] 2019 Sep; Vol. 22 (9), pp. 1383-1388. Date of Electronic Publication: 2019 Jul 29.