Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Krajnc, Matej"'
In the recently proposed Graph Vertex Model (GVM), cellular rearrangements are implemented as local graph transformations of the cell aggregate, represented by a knowledge graph [1]. This study extends GVM to incorporate cell division, a critical bio
Externí odkaz:
http://arxiv.org/abs/2408.07551
The mechanics of epithelial tissues, which is governed by forces generated in various cell domains, is often investigated using two-dimensional models that account for the apically-positioned actomyosin structures but neglect basolateral mechanics. W
Externí odkaz:
http://arxiv.org/abs/2402.19312
Autor:
Sarkar, Tanmoy, Krajnc, Matej
Cell rearrangements are fundamental mechanisms driving large-scale deformations of living tissues. In three-dimensional (3D) space-filling cell aggregates, cells rearrange through local topological transitions of the network of cell-cell interfaces,
Externí odkaz:
http://arxiv.org/abs/2309.04818
We investigate the elasticity of unsupported epithelial monolayer and we discover that unlike a thin solid plate, which wrinkles if geometrically incompatible with the underlying substrate, the epithelium may do so even in absence of the substrate. F
Externí odkaz:
http://arxiv.org/abs/2210.11883
Publikováno v:
Eur. Phys. J. E 44, 99 (2021)
Using a three-dimensional active vertex model, we numerically study the shapes of strained unsupported epithelial monolayers subject to active junctional noise due to stochastic binding and unbinding of myosin. We find that while uniaxial, biaxial, a
Externí odkaz:
http://arxiv.org/abs/2102.02224
Active cell-junction remodeling is important for tissue morphogenesis, yet its underlying physics is not understood. We study a mechanical model that describes junctions as dynamic active force dipoles. Their instability can trigger cell intercalatio
Externí odkaz:
http://arxiv.org/abs/2101.07058
Autor:
Popkova, Anna, Andrenšek, Urška, Pagnotta, Sophie, Ziherl, Primož, Krajnc, Matej, Rauzi, Matteo
Publikováno v:
In Developmental Cell 5 February 2024 59(3):400-414
Autor:
Sarkar, Tanmoy1 (AUTHOR), Krajnc, Matej1 (AUTHOR) matej.krajnc@ijs.si
Publikováno v:
PLoS Computational Biology. 5/14/2024, Vol. 20 Issue 5, p1-24. 24p.
Autor:
Zankoc, Clement, Krajnc, Matej
Macroscopic properties and shapes of biological tissues depend on the remodelling of cell-cell junctions at the microscopic scale. We propose a theoretical framework that couples a vertex model of solid confluent tissues with the dynamics describing
Externí odkaz:
http://arxiv.org/abs/2007.02657