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Autor:
Stockley ML, Benedetti G, Blencowe P, Boulton SJ, Boyd SM, Calder M, Charles MD, Edwardes LV, Ekwuru T, Ferdinand A, Finch H, Galbiati A, Geo L, Grande D, Grinkevich V, Higgins GS, Holliday ND, Krajewski WW, MacDonald E, Majithiya JB, McCarron H, McWhirter CL, Patel V, Pedder C, Rajendra E, Ranzani M, Rigoreau LJM, Robinson HMR, Schaedler T, Sirina J, Smith GCM, Swarbrick ME, Turnbull AP, Willis S, Zemla A, Heald RA
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2023 Feb 23. Date of Electronic Publication: 2023 Feb 23.
Autor:
Stockley ML; Artios Pharma Ltd., B940, Babraham Research Campus, CambridgeCB22 3FH, U. K., Ferdinand A; Cancer Research Horizons Therapeutic Innovation, Jonas Webb Building, Babraham Research Campus, CambridgeCB22 3AT, U. K., Benedetti G; Artios Pharma Ltd., B940, Babraham Research Campus, CambridgeCB22 3FH, U. K., Blencowe P; Cancer Research Horizons Therapeutic Innovation, Jonas Webb Building, Babraham Research Campus, CambridgeCB22 3AT, U. K., Boyd SM; CompChem Solutions Ltd, St John's Innovation Centre, Cowley Rd, CambridgeCB4 0WS, U. K., Calder M; Cancer Research Horizons Therapeutic Innovation, Jonas Webb Building, Babraham Research Campus, CambridgeCB22 3AT, U. K., Charles MD; Cancer Research Horizons Therapeutic Innovation, Jonas Webb Building, Babraham Research Campus, CambridgeCB22 3AT, U. K., Edwardes LV; Artios Pharma Ltd., B940, Babraham Research Campus, CambridgeCB22 3FH, U. K., Ekwuru T; Cancer Research Horizons Therapeutic Innovation, Jonas Webb Building, Babraham Research Campus, CambridgeCB22 3AT, U. K., Finch H; Artios Pharma Ltd., B940, Babraham Research Campus, CambridgeCB22 3FH, U. K., Galbiati A; Artios Pharma Ltd., B940, Babraham Research Campus, CambridgeCB22 3FH, U. K., Geo L; Artios Pharma Ltd., B940, Babraham Research Campus, CambridgeCB22 3FH, U. K., Grande D; Artios Pharma Ltd., B940, Babraham Research Campus, CambridgeCB22 3FH, U. K., Grinkevich V; Artios Pharma Ltd., B940, Babraham Research Campus, CambridgeCB22 3FH, U. K., Holliday ND; Excellerate Bioscience Ltd., BioCity, Pennyfoot Street, NottinghamNG1 1GF, U. K., Krajewski WW; Cancer Research Horizons Therapeutic Innovation, The Francis Crick Institute, 1 Midland Road, LondonNW1 1AT, U. K., MacDonald E; Cancer Research Horizons Therapeutic Innovation, Jonas Webb Building, Babraham Research Campus, CambridgeCB22 3AT, U. K., Majithiya JB; Artios Pharma Ltd., B940, Babraham Research Campus, CambridgeCB22 3FH, U. K., McCarron H; Cancer Research Horizons Therapeutic Innovation, Jonas Webb Building, Babraham Research Campus, CambridgeCB22 3AT, U. K., McWhirter CL; Artios Pharma Ltd., B940, Babraham Research Campus, CambridgeCB22 3FH, U. K., Patel V; Excellerate Bioscience Ltd., BioCity, Pennyfoot Street, NottinghamNG1 1GF, U. K., Pedder C; Cancer Research Horizons Therapeutic Innovation, Jonas Webb Building, Babraham Research Campus, CambridgeCB22 3AT, U. K., Rajendra E; Artios Pharma Ltd., B940, Babraham Research Campus, CambridgeCB22 3FH, U. K., Ranzani M; Artios Pharma Ltd., B940, Babraham Research Campus, CambridgeCB22 3FH, U. K., Rigoreau LJM; Cancer Research Horizons Therapeutic Innovation, Jonas Webb Building, Babraham Research Campus, CambridgeCB22 3AT, U. K., Robinson HMR; Artios Pharma Ltd., B940, Babraham Research Campus, CambridgeCB22 3FH, U. K., Schaedler T; Artios Pharma Ltd., B940, Babraham Research Campus, CambridgeCB22 3FH, U. K., Sirina J; Excellerate Bioscience Ltd., BioCity, Pennyfoot Street, NottinghamNG1 1GF, U. K., Smith GCM; Artios Pharma Ltd., B940, Babraham Research Campus, CambridgeCB22 3FH, U. K., Swarbrick ME; Cancer Research Horizons Therapeutic Innovation, Jonas Webb Building, Babraham Research Campus, CambridgeCB22 3AT, U. K., Turnbull AP; Cancer Research Horizons Therapeutic Innovation, The Francis Crick Institute, 1 Midland Road, LondonNW1 1AT, U. K., Willis S; Cancer Research Horizons Therapeutic Innovation, The Francis Crick Institute, 1 Midland Road, LondonNW1 1AT, U. K., Heald RA; Artios Pharma Ltd., B940, Babraham Research Campus, CambridgeCB22 3FH, U. K.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2022 Oct 27; Vol. 65 (20), pp. 13879-13891. Date of Electronic Publication: 2022 Oct 06.
Autor:
Ruiz EJ; Adult stem cell laboratory, The Francis Crick Institute, London, United Kingdom., Pinto-Fernandez A; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Turnbull AP; London Bioscience Innovation Centre, CRUK Therapeutic Discovery Laboratories, London, United Kingdom., Lan L; Adult stem cell laboratory, The Francis Crick Institute, London, United Kingdom., Charlton TM; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Scott HC; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Damianou A; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Vere G; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Riising EM; Adult stem cell laboratory, The Francis Crick Institute, London, United Kingdom., Da Costa C; Adult stem cell laboratory, The Francis Crick Institute, London, United Kingdom., Krajewski WW; London Bioscience Innovation Centre, CRUK Therapeutic Discovery Laboratories, London, United Kingdom., Guerin D; FORMA Therapeutics, Watertown, United Kingdom., Kearns JD; FORMA Therapeutics, Watertown, United Kingdom., Ioannidis S; FORMA Therapeutics, Watertown, United Kingdom., Katz M; FORMA Therapeutics, Watertown, United Kingdom., McKinnon C; FORMA Therapeutics, Watertown, United Kingdom., O'Connell J; FORMA Therapeutics, Watertown, United Kingdom., Moncaut N; Genetic Manipulation Service, The Francis Crick Institute, London, United States., Rosewell I; Genetic Manipulation Service, The Francis Crick Institute, London, United States., Nye E; Adult stem cell laboratory, The Francis Crick Institute, London, United Kingdom., Jones N; London Bioscience Innovation Centre, CRUK Therapeutic Discovery Laboratories, London, United Kingdom., Heride C; London Bioscience Innovation Centre, CRUK Therapeutic Discovery Laboratories, London, United Kingdom., Gersch M; Max Planck Institute of Molecular Physiology, Dortmund, Germany., Wu M; FORMA Therapeutics, Watertown, United Kingdom., Dinsmore CJ; FORMA Therapeutics, Watertown, United Kingdom., Hammonds TR; London Bioscience Innovation Centre, CRUK Therapeutic Discovery Laboratories, London, United Kingdom., Kim S; Incyte, Wilmington, United States., Komander D; Ubiquitin Signalling Division, Walter and Eliza Hall Institute of Medical Research, Royal Parade, and Department of Medical Biology, University of Melbourne, Melbourne, Australia., Urbe S; Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom., Clague MJ; Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom., Kessler BM; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Behrens A; Adult stem cell laboratory, The Francis Crick Institute, London, United Kingdom.; Cancer Stem Cell Laboratory, Institute of Cancer Research, London, United Kingdom.; Imperial College, Division of Cancer, Department of Surgery and Cancer, London, United Kingdom.; Convergence Science Centre, Imperial College, London, United Kingdom.
Publikováno v:
ELife [Elife] 2021 Oct 12; Vol. 10. Date of Electronic Publication: 2021 Oct 12.
Autor:
Turnbull AP; CRUK Therapeutic Discovery Laboratories, London Bioscience Innovation Centre, London NW1 0NH, UK., Ioannidis S; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA., Krajewski WW; CRUK Therapeutic Discovery Laboratories, London Bioscience Innovation Centre, London NW1 0NH, UK., Pinto-Fernandez A; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7FZ, UK., Heride C; Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Crown Street, Liverpool L69 3BX, UK., Martin ACL; CRUK Therapeutic Discovery Laboratories, Jonas Webb Building, Babraham Research Campus, Cambridge CB22 3AT, UK., Tonkin LM; CRUK Therapeutic Discovery Laboratories, Jonas Webb Building, Babraham Research Campus, Cambridge CB22 3AT, UK., Townsend EC; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA., Buker SM; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA., Lancia DR; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA., Caravella JA; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA., Toms AV; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA., Charlton TM; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7FZ, UK., Lahdenranta J; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA., Wilker E; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA., Follows BC; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA., Evans NJ; CRUK Therapeutic Discovery Laboratories, London Bioscience Innovation Centre, London NW1 0NH, UK., Stead L; Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Crown Street, Liverpool L69 3BX, UK., Alli C; CRUK Therapeutic Discovery Laboratories, Jonas Webb Building, Babraham Research Campus, Cambridge CB22 3AT, UK., Zarayskiy VV; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA., Talbot AC; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA., Buckmelter AJ; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA., Wang M; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA., McKinnon CL; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA., Saab F; CRUK Therapeutic Discovery Laboratories, London Bioscience Innovation Centre, London NW1 0NH, UK., McGouran JF; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7FZ, UK., Century H; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7FZ, UK., Gersch M; Medical Research Council Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK., Pittman MS; CRUK Therapeutic Discovery Laboratories, London Bioscience Innovation Centre, London NW1 0NH, UK., Marshall CG; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA., Raynham TM; CRUK Therapeutic Discovery Laboratories, London Bioscience Innovation Centre, London NW1 0NH, UK., Simcox M; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA., Stewart LMD; CRUK Therapeutic Discovery Laboratories, London Bioscience Innovation Centre, London NW1 0NH, UK., McLoughlin SB; CRUK Therapeutic Discovery Laboratories, Jonas Webb Building, Babraham Research Campus, Cambridge CB22 3AT, UK., Escobedo JA; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA., Bair KW; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA., Dinsmore CJ; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA., Hammonds TR; CRUK Therapeutic Discovery Laboratories, London Bioscience Innovation Centre, London NW1 0NH, UK., Kim S; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA., Urbé S; Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Crown Street, Liverpool L69 3BX, UK., Clague MJ; Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Crown Street, Liverpool L69 3BX, UK., Kessler BM; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7FZ, UK., Komander D; Medical Research Council Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK.
Publikováno v:
Nature [Nature] 2017 Oct 26; Vol. 550 (7677), pp. 481-486. Date of Electronic Publication: 2017 Oct 18.
Autor:
Krajewski WW; 1] Division of Structural Biology, Institute of Cancer Research, Chester Beatty Laboratories, 237 Fulham Road, London SW3 6JB, UK [2] CRT Discovery Laboratories, Department of Biological Sciences, Birkbeck, University of London, London WC1E 7HX, UK., Fu X; Division of Structural Biology, Institute of Cancer Research, Chester Beatty Laboratories, 237 Fulham Road, London SW3 6JB, UK., Wilkinson M; Division of Structural Biology, Institute of Cancer Research, Chester Beatty Laboratories, 237 Fulham Road, London SW3 6JB, UK., Cronin NB; Division of Structural Biology, Institute of Cancer Research, Chester Beatty Laboratories, 237 Fulham Road, London SW3 6JB, UK., Dillingham MS; School of Biochemistry, University of Bristol, Medical Sciences Building, University Walk, Bristol BS8 1TD, UK., Wigley DB; Division of Structural Biology, Institute of Cancer Research, Chester Beatty Laboratories, 237 Fulham Road, London SW3 6JB, UK.
Publikováno v:
Nature [Nature] 2014 Apr 17; Vol. 508 (7496), pp. 416-9. Date of Electronic Publication: 2014 Mar 16.
Autor:
Saikrishnan K; Division of Structural Biology, Institute of Cancer Research, Chester Beatty Laboratories, London, UK., Yeeles JT, Gilhooly NS, Krajewski WW, Dillingham MS, Wigley DB
Publikováno v:
The EMBO journal [EMBO J] 2012 Mar 21; Vol. 31 (6), pp. 1568-78. Date of Electronic Publication: 2012 Feb 03.
Autor:
Nilsson MT; Department of Cell and Molecular Biology, Uppsala University, Biomedical Center, Sweden., Krajewski WW, Yellagunda S, Prabhumurthy S, Chamarahally GN, Siddamadappa C, Srinivasa BR, Yahiaoui S, Larhed M, Karlén A, Jones TA, Mowbray SL
Publikováno v:
Journal of molecular biology [J Mol Biol] 2009 Oct 23; Vol. 393 (2), pp. 504-13. Date of Electronic Publication: 2009 Aug 18.
Autor:
Nordqvist A; Division of Organic Pharmaceutical Chemistry, Department of Medicinal Chemistry, Uppsala University, Biomedical Centre, Box 574, SE-751 23 Uppsala, Sweden., Nilsson MT, Röttger S, Odell LR, Krajewski WW, Evalena Andersson C, Larhed M, Mowbray SL, Karlén A
Publikováno v:
Bioorganic & medicinal chemistry [Bioorg Med Chem] 2008 May 15; Vol. 16 (10), pp. 5501-13. Date of Electronic Publication: 2008 Apr 11.
Autor:
Krajewski WW; Department of Cell and Molecular Biology, Biomedical Center, Uppsala University, Box 596, SE-751 24 Uppsala, Sweden., Collins R, Holmberg-Schiavone L, Jones TA, Karlberg T, Mowbray SL
Publikováno v:
Journal of molecular biology [J Mol Biol] 2008 Jan 04; Vol. 375 (1), pp. 217-28. Date of Electronic Publication: 2007 Oct 17.